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Akram M, Rashid A, Munir N, Zainab R, Khalil M T, Laila U, et al . Eclipta alba Species Role in Natural Medicine. pbp 2022; 4 (2) :38-42
URL: http://pbp.medilam.ac.ir/article-1-144-en.html
1- Department of Eastern Medicine, Government College University Faisalabad-Pakistan , Muhammad Akram
2- Faculty of Medical Sciences, Government College University Faisalabad Pakistan
3- Department of Biomedical Lab Sciences, School of Health Sciences, University of Management and Technology, Lahore-Pakistan
4- Department of Eastern Medicine, Government College University Faisalabad-Pakistan
5- Department of Eastern Medicine, Government College University Faisalabad-Pakistan.
6- College of Allied Heath Professional, Government College University Faisalabad-Pakistan
Abstract:   (1155 Views)
Objectives: Eclipta alba is a seasonal medicinal plant native to Pakistan and its associated countries, vastly present in tropical and sub-tropical regions, having multi-branched white flowers. Almost all parts of E. alba are being used in the treatment of various ailments due to the presence of wide range of phytochemical constituents. Therefore, this review article has been written to compile to therapeutic applications of said medicinal herb.
Material and Methods: Selective reference material was selected using different search engines like PubMed, NCBI, Google Scholar, Science direct etc.by putting Keywords including E. alba, its medicinal uses, nutritional benefits of E. alba, diseases, and E. alba etc.
Results: Researches revealed that traditionally E. alba is well known to cure several diseases like hair growth disorders, efficacious hyperglycemic activity through inhibition of alpha-glucosidase and aldose reductase as well as by stimulating insulin secretion. Obesity is considered as the mother of disease, and many health occurs from obesity, so by its lipid-lowering activity, it lowers all types of fat. Mosquitoes as vectors cause serious human diseases like malaria, filariasis, Japanese encephalitis, yellow fever, dengue fever and chikungunya have become major causes of mortality and morbidity among people. E. alba has insecticidal, larvicidal and ovicidal activity to control the mosquitoes borne diseases. Liver ailments such as liver enlargement, hepatitis and cirrhosis of liver have been a major issue for public issue. Wedelolactone, the chemical constituent of E. alba is very potent in liver ailment and due to its anti-viral activity, it can kill the virus responsible for hepatitis and other viruses as well. E. alba has efficacious anti-inflammatory activity, because of anti-oxidant constituents present in this herb. A very important role of this herbal plant is in hair growth promotion activity, so it has major value to treat hair problems such as alopecia, thinning of hair and hair color problems. It activates the hair follicles and enhances the hairs growth. It also has anti-hemorrhagic, antibiotic, antiseptic, anti-microbial activity and has very in snake bite scorpion sting.
Conclusion: Although, E. alba has several health-related benefits, but still more research is under consideration in scientific community related to its phytochemical constituents and mechanism of actions.
Full-Text [PDF 1731 kb]   (287 Downloads)    
Type of Study: Research | Subject: Herbal Drugs
Received: 2022/07/19 | Accepted: 2022/12/1 | Published: 2022/12/1

References
1. Bakht J, Islam A, Shafi M. Antimicrobial potential of Eclipta alba by well diffusion method. Pak. J. Bot. 2011; 43:161-166.
2. Manvar D, Mishra M, Kumar S, Pandey VN. Identification and evaluation of anti hepatitis C virus phytochemicals from Eclipta alba. J Ethnopharmacol. 2012;144(3):545-54. doi: 10.1016/j.jep.2012.09.036
3. Jayathirtha MG, Mishra SH. Preliminary immunomodulatory activities of methanol extracts of Eclipta alba and Centella asiatica. Phytomed. 2004;11(4):361-365. doi: 10.1078/0944711041495236
4. Saxena AK, Singh B, Anand KK. Hepatoprotective effects of Eclipta alba on subcellular levels in rats. J Ethnopharmacol. 1993;40(3):155-161.
5. Chandan S, Umesha S, Balamurugan V. Antileptospiral, antioxidant and DNA damaging properties of Eclipta alba and Phyllanthus amarus. 2012:6(3):45-50. doi.org/10.4172/scientificreports.231
6. Jadhav VM, Thorat RM, Kadam VJ, Salaskar KP. Chemical composition, pharmacological activities of Eclipta alba. Journal of Pharmacy research. 2009;2(8):1129-1131.
7. Mithun NM, Shashidhara S, Vivek Kumar R. Eclipta alba (L.) A review on its phytochemical and pharmacological profile. Pharmacol. 2011;1(1):345-357.
8. Hussain F, Rana Z, Shafique H, Malik A, Hussain Z. Phytopharmacological potential of different species of Morus alba and their bioactive phytochemicals: A review. Asian Pacific journal of tropical biomedicine. 2017;7(10):950-956.doi.org/10.1016/j.apjtb.2017.09.015
9. Wagner H, Geyer B, Kiso Y, Hikino H, Rao GS. Coumestans as the main active principles of the liver drugs Eclipta alba and Wedelia calendulacea1. Planta Medica. 1986;52(05):370-374.
10. Dalal S. Application of Metabolic Engineering to The Production of Wedelolactone. J Ind Bot Soc. 2010;89(4):297-302. doi: 10.3390/molecules13081722
11. Roy RK, Thakur M, Dixit VK. Hair growth promoting activity of Eclipta alba in male albino rats. Arch Dermatol Res;300(7):357-364. DOI: 10.1007/s00403-008-0860-3
12. Datta K, Singh AT, Mukherjee A, Bhat B, Ramesh B, Burman AC. Eclipta alba extract with potential for hair growth promoting activity. J Ethnopharmacol. 2009;124(3):450-456. doi: 10.1016/j.jep.2009.05.023
13. Chokotia LS, Vashistha P, Sironiya R, Matoli H. Pharmacological activities of Eclipta alba (L.). Inter J Res Develop Pharm Life Sci,2013;2(4):499-502. doi: 10.1155/2017/9094641
14. Kumar SS, Sivakumar T, Chandrasekar MJ, Suresh B. Evaluation of Anti–Inflammatory Activity of Eclipta alba in rats. Ancient Sci Life. 2005;24(3):112. PMCID: PMC3330935
15. Singh A, Singh A, Dwivedi V. Antidiabetic effect of Eclipta alba. Inter J Sci Eng Res.2014;5(2):1462-1466. doi: 10.1080/14786419.2012.662648
16. Yadav NK, Arya RK, Dev K, Sharma C, Hossain Z, Meena S, Arya KR, Gayen JR, Datta D, Singh RK. Alcoholic extract of Eclipta alba shows in vitro antioxidant and anticancer activity without exhibiting toxicological effects. Oxid Med Cell Long. 2017;6(7):45-50. doi: 10.1155/2017/9094641
17. Govindarajan M, Karuppannan P. Mosquito larvicidal and ovicidal properties of Eclipta alba (L.) Hassk (Asteraceae) against chikungunya vector, Aedes aegypti (Linn.)(Diptera: Culicidae). Asian Pac J Trop Med, 2011;4(1):24-28. doi: 10.1016/S1995-7645(11)60026-6
18. Feng L, Zhai YY, Xu J, Yao WF, Cao YD, Cheng FF, Bao BH, Zhang L. A review on traditional uses, phytochemistry and pharmacology of Eclipta prostrata (L.) L. J Ethnopharmacol. 2019;5(2):45-55. doi: 10.1016/j.jep.2019.112109
19. 1Lunavath V, Mamidala E. Preliminary phytochemical screening and antibacterial studies of the leaves of Eclipta alba (L). Int J Pharma Biosci. 2013; 4: 380-384. PMID: 27166527

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