Volume 7, Issue 3 (7-2025)
pbp 2025, 7(3): 68-77 |
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Mkangara M. GC-MS Analysis of Bioactive Compounds in Ethyl acetate and Chloroform extracts of Aloe rabaiensis Rendle. pbp 2025; 7 (3) :68-77
URL: http://pbp.medilam.ac.ir/article-1-209-en.html
URL: http://pbp.medilam.ac.ir/article-1-209-en.html
Faculty of Science, Technology and Environmental Studies, The Open University of Tanzania, Dar es Salaam, Tanzania , mkangaram@yahoo.com
Abstract: (222 Views)
Objective: Plants have been a good source of lead compounds for nutraceutical and therapeutic potentials against ailments of human and animal importance since the introduction of man on earth. The lead compounds continue to be precursors in developing drugs with insignificant side effects and replace synthetic medicine. Several phytochemical compounds have been reported in different species of Aloe belonging to the family Asphodelaceae. The established phytoconstituents from the genus Aloe possess several activities, including antiviral, antibacterial, anticancer, neuroprotective, and antioxidant properties. However, there is limited information related to phytochemicals from Aloe rabaiensis Rendle.
Methods: This is the first study investigating the phytoconstituents in A. rabaiensis from Tanzania. Gas chromatography-mass spectrometry (GC-MS) analysis of A. rabaiensis leaf extracts was performed using GC-MS equipment (Agilent Technologies).
Results: The GC-MS analysis demonstrated the presence of fourteen and six compounds from the leaf’s ethyl acetate and chloroform extracts of A. rabaiensis, respectively.
Conclusion: The compounds belong to different classes, including amines, esters, carboxylic acid, ketone, phenol, alkane and alcohol. No common compound(s) was/were identified from both extracts. The identified phytoconstituents, backed with reported ethnomedical and ethnoveterinary use of A. rabaiensis are evidence, thus, significant precursors for drug development.
Methods: This is the first study investigating the phytoconstituents in A. rabaiensis from Tanzania. Gas chromatography-mass spectrometry (GC-MS) analysis of A. rabaiensis leaf extracts was performed using GC-MS equipment (Agilent Technologies).
Results: The GC-MS analysis demonstrated the presence of fourteen and six compounds from the leaf’s ethyl acetate and chloroform extracts of A. rabaiensis, respectively.
Conclusion: The compounds belong to different classes, including amines, esters, carboxylic acid, ketone, phenol, alkane and alcohol. No common compound(s) was/were identified from both extracts. The identified phytoconstituents, backed with reported ethnomedical and ethnoveterinary use of A. rabaiensis are evidence, thus, significant precursors for drug development.
Type of Study: Research |
Subject:
Bioactive Compounds
Received: 2023/11/14 | Accepted: 2024/04/13 | Published: 2025/07/27
Received: 2023/11/14 | Accepted: 2024/04/13 | Published: 2025/07/27
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