en Bioactive Compounds پژوهشي Research <span style="font-size:10pt"><span style="line-height:115%"><span style="font-family:&quot;Optima&quot;,serif"><span style="color:black"><b><span style="font-size:9.0pt"><span style="line-height:115%"><span style="font-family:&quot;Times New Roman&quot;,serif">Objective:</span></span></span></b><span style="font-size:9.0pt"><span style="line-height:115%"><span style="font-family:&quot;Times New Roman&quot;,serif"> <i>Acmella paniculata </i>(Wall. Ex DC.) R. K. Jansen, also known as Akkalkadha or toothache plant is an important medicinal herb of the Asteraceae family that grows in the tropics and subtropics of the world.</span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:115%"><span style="font-family:&quot;Optima&quot;,serif"><span style="color:black"><b><span style="font-size:9.0pt"><span style="line-height:115%"><span style="font-family:&quot;Times New Roman&quot;,serif">Material and Methods:</span></span></span></b><span style="font-size:9.0pt"><span style="line-height:115%"><span style="font-family:&quot;Times New Roman&quot;,serif"> The present phytochemical investigation aimed at evaluating the impact of different solvents on extraction yields, ash analysis, fluorescence analysis and phytochemical compounds from flower drug of&nbsp;<i>A. paniculata </i>plant. The results indicate that solvents have a significant impact in the yield of extraction.</span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:115%"><span style="font-family:&quot;Optima&quot;,serif"><span style="color:black"><b><span style="font-size:9.0pt"><span style="line-height:115%"><span style="font-family:&quot;Times New Roman&quot;,serif">Results:</span></span></span></b><span style="font-size:9.0pt"><span style="line-height:115%"><span style="font-family:&quot;Times New Roman&quot;,serif"> Resulting in the higher extraction yield in solvent distilled water and ethanol. Flavonoids, alkaloids, tannins, saponins, cardiac glycosides, and terpenoids are found in the crude flower drug of the plant.</span></span></span></span></span></span></span><br> <b><span style="font-size:9.0pt"><span style="line-height:107%"><span style="font-family:&quot;Times New Roman&quot;,serif">Conclusion:</span></span></span></b><span style="font-size:9.0pt"><span style="line-height:107%"><span style="font-family:&quot;Times New Roman&quot;,serif"> The present study is useful in drug standardization, identifying the adulteration in the Ayurvedic medicines from this plant.</span></span></span> ,Acmella paniculata,ash analysis,extraction yields,flower drug,fluorescence analysis,phytochemical investigation. 60 67 http://pbp.medilam.ac.ir/browse.php?a_code=A-10-434-1&slc_lang=en&sid=1 Bhagwan Mahale bhagwanmahale3@gmail.com 10031947532846002127 0000000319175161 Yes MGV Arts Science and Commerce College Surgana Dist Nashik India Sagar Palwe sagarpalwe@gmail.com 10031947532846002128 0000000270750590 No MGV Arts Science and Commerce College Surgana Dist NAshik India 422211 Asahish Gajbhiye avigaj023@gmail.com 10031947532846002129 000000030811147X No MGV Arts Science and Commerce College Surgana Dist Nashik India 422211 Vinayak Bagul vrbchem28@gmail.com 10031947532846002130 0000000294063541 No MGV Arts Science and Commerce College Surgana Dist Nashik India 422211 VInayak Kadam kadamvv18@gmail.com 10031947532846002131 0000000207170008 No MGV Arts Science and Commerce College Surgana Dist Nashik India 422211