en Biotechnology پژوهشي Research <span style="font-size:12px;"><span style="font-family:Tahoma;"><span style="line-height:150%"><span new="" roman="" times=""><span style="color:black"><b>Objectives:</b> One of the application areas of nanobiotechnology is the use of silver nanoparticles (Nanosilver particles) for a new solution in medical treatments. In the present study, the researchers investigate the effect of nano silver particles of the aqueous extract of Artemisia aucheri on skin wound healing among male rats<span dir="RTL" lang="AR-SA"><span style="line-height:150%">.</span></span></span></span></span><br> <span style="line-height:150%"><span new="" roman="" times=""><span style="color:black"><b>Material and Methods:</b> After creating wounds in 48 rats, they were randomly divided into 6 groups<span dir="RTL" lang="AR-SA"><span style="line-height:150%">.</span></span> Treated with 0.2% AgNPs ointment, 0.2% AgSO4 ointment, &nbsp;&nbsp;0.2% A. aucheri ointment, 3% tetracycline ointment, Eucerin basal ointment, and untreated control group. The tested groups were treated for ten days.</span></span></span><br> <span style="line-height:150%"><span new="" roman="" times=""><span style="color:black"><b>Results:</b> Treatment with AgNPs ointment significantly increased the amount of vascular contraction, hexose amine and hydroxyproline, and fibrocyte and fibrocyte to fibroblast ratio. Also, in the mentioned group, the wound area and the total number of cells, neutrophils and lymphocytes decreased significantly compared to other groups.&nbsp;</span></span></span><br> <b><span style="line-height:107%"><span new="" roman="" times="">Conclusion:</span></span></b><span style="line-height:107%"><span new="" roman="" times=""> The nano silver particles of the aqueous extract of A. aucheri</span></span> <span style="line-height:107%"><span new="" roman="" times="">accelerate the healing process of skin wounds and reduce the time required for complete wound healing.</span></span></span></span> ,Railway,Seedling Dry Weight,Soil,Toxicity 8 13 http://pbp.medilam.ac.ir/browse.php?a_code=A-10-488-1&slc_lang=en&sid=1 Muhammad Shafiq shafiqeco@yahoo.com 10031947532846004961 0000000204888946 Yes University of Karachi Ziaurrehman Farooqui farooqi_bot@yahoo.com 10031947532846004962 0000000343203871 No University of Karachi Muhammad Zafar Iqbal mziqbalbotuokpk@yahoo.com 10031947532846004963 0000000225755085 No University of Karachi Mohammad Athar atariq@cdfa.ca.gov 10031947532846004964 0000000227055322 No California Department of Food and Agriculture Muhammad Kabir muhammad.kabir@uos.edu.pk 10031947532846004965 0000000284042675 No Department of Biological Sciences, University of Sargodha, Sub-campus Bhakkar, Pakistan