fa <span style="font-family:Times New Roman;"><span style="font-size:14px;"><span style="unicode-bidi:embed"><span style="line-height:107%">This review meticulously examines the antimicrobial effects of medicinal plants on Staphylococcus aureus and underscores their potential in overcoming the challenge of drug resistance. With a plethora of plant species known for their antimicrobial properties, exploring alternative solutions to combat bacterial infections is imperative. The review emphasizes the importance of investigating plant-derived compounds that can effectively inhibit bacterial growth through unique mechanisms and discusses the synergistic effects of combining multiple compounds from plant extracts. Researchers are actively working on isolating novel bioactive chemicals from plants to serve as effective alternatives to traditional antibiotics. The study highlights the critical role of herbal medicines in addressing resistant strains of Staphylococcus aureus and stresses the necessity for further research to develop innovative treatment approaches.</span></span></span></span><br> &nbsp; Medicinal plants, Staphylococcus aureus, antimicrobial effects, drug resistance, bioactive compounds, alternative treatments, multi-resistant strains 31 45 http://pbp.medilam.ac.ir/browse.php?a_code=A-10-25-51&slc_lang=fa&sid=1 Elahe Zarif Fakoor 10031947532846003967 10031947532846003967 No General Biology. Mashhad, Iran, Payam-e Noor University of Mashhad, Iran Samad Rezvanimanesh 10031947532846003968 10031947532846003968 No Cellular and Molecular Research, Yasuj University of Medical Sciences, Yasuj, Iran Shiva Ahmadishoar 10031947532846003969 10031947532846003969 No Department of Microbiology, Malekan Branch, Islamic Azad University, Malekan, Iran Mahtab Mehboodi 10031947532846003970 10031947532846003970 No Department of Medical Microbiology (Bacteriology & Virology), Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran Hamid Reza Mardani 10031947532846003971 10031947532846003971 No Department of Microbiology, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran Samad Rastmanesh 10031947532846003972 10031947532846003972 No Department of Bacteriology and Virology, School of Medicine, Tabriz university of Medical Science, Tabriz, Iran Mohammad Amin Niknejad 10031947532846003973 10031947532846003973 No Department of Microbiology, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran Rosita Yousefian Mobarekeh 10031947532846003974 10031947532846003974 No Department of Microbiology, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran Shiva Eskandari 10031947532846003975 10031947532846003975 No Department of Microbiology, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran Maede Shirazi 10031947532846003976 10031947532846003976 Yes Department of Microbiology, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran Behnam Poureslamfar 10031947532846003977 10031947532846003977 No Department of Biology, Faculty of Science, Yasouj University, Yasouj, Iran