en Herbal Drugs كاربردي Review/Systemtic review <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><b>Objective:</b> The genus <i>Satureja</i> [Lamiaceae], commonly referred to as savory, has been traditionally valued for its medicinal properties, particularly its antimicrobial activity.<br> <b>Methodology: </b>Methodology: In this review study, the key words satureja, antimicrobial resistance, antibiotics, carvacrol, thymol, multidrug-resistant were used to search for articles. Databases such as Google Scholar, SID, Magiran, PubMed, Scopus were used for searching.<br> <b>Results</b>: Various species of <i>Satureja</i> are rich in bioactive compounds such as thymol, carvacrol, and terpenoids, which exhibit strong antibacterial, antifungal, and antiviral properties. These essential oils primarily act by disrupting bacterial cell membranes, inhibiting biofilm formation, and interfering with bacterial metabolism and DNA replication. This review critically examines the antimicrobial properties of nine Satureja species, focusing on their bioactive compounds, molecular mechanisms, and potential applications.<br> <b>Conclusion:</b> Given the growing challenge of antimicrobial resistance (AMR), the therapeutic potential of Satureja is discussed in the context of alternative antimicrobial strategies and industrial applications.</span></span><br> <br> &nbsp;</div> Satureja,Antimicrobial resistance,Antibiotics,Carvacrol,Thymol,Multidrug-resistant 39 49 http://pbp.medilam.ac.ir/browse.php?a_code=A-10-1495-1&slc_lang=en&sid=1 Ahdiyeh Saghabashi Saghabashiahd@yahoo.com 10031947532846005636 10031947532846005636 No Department of Microbiology, Faculty of Sciences, Agriculture and Modern Technology, Shiraz Branch, Islamic Azad University, Shiraz, Iran Atena Sadeghi Sadeghiatenaa@yahoo.com 10031947532846005637 10031947532846005637 No Department of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran Mohammad Ghodratie MohammadGhodrati@gmail.com 10031947532846005638 10031947532846005638 No Department of Medical Microbiology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran. Hosna hatami Hosnatam@gmail.com 10031947532846005639 10031947532846005639 No Department of medical biotechnology, Kermanshah university of medical science, Kermanshah,Iran Seyedeh Faride Alavi Rostami SeyedehAlavir@yahoo.com 10031947532846005640 10031947532846005640 No Department of Microbiology, Faculty of Biological Sciences, Islamic Azad University Tehran-North Branch, Tehran, Iran. Mahdi Yazdehi MahdiYazdehii1@yahoo.com 10031947532846005641 10031947532846005641 No 3 Department of Medical Microbiology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran. Ebrahim Mahmoudi EbrahimMahmoudi55@yahoo.com 10031947532846005642 10031947532846005642 No School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Saina Najafi Sainanajaf@yahoo.com 10031947532846005643 10031947532846005643 No Department of Microbiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Zahra Mottaghiyan university.ac55@gmail.com 10031947532846005644 10031947532846005644 Yes , Department of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran