en Bioactive Compounds پژوهشي Research <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:115%"><b>Objectives:</b> Aloe-emodin is one the of dynamic compounds and has several pharmacological activities such as anti-inflammatory, antitumor, antiviral, anticancer, antifungal antidiabetic, and antipsoriatic. It is an important ingredient in several traditional herbal formulations. This study was done for qualitative and quantitative standardization of the Aloe-Emodin compound in Aloe sinkatana plant extract.</span><br> <span style="line-height:115%"><b>Methods:</b> TLC (Thin layer chromatography) and UV-visible spectroscopic methods were developed for both qualitative and quantitative standardization of aloe emodine in Aloe sinkatana plant extract.</span><br> <span style="line-height:115%"><b>Results:</b> The results indicated that TLC and UV-visible spectroscopic methods are simple, accurate, sensitive, precise, and reproducible.</span><br> <span style="line-height:115%"><b>Conclusion:</b> In conclusion, we can say that the TLC and UV-visible spectroscopic methods can be effectively used for standardizing aloe-emodin in various pharmaceutical dosage forms.</span></span></span><br> <br> &nbsp;</div> Aloe-emodin,Aloe sinkatana plant,Standardization,Thin layer chromatography,and UV-visible spectroscopic. 1 9 http://pbp.medilam.ac.ir/browse.php?a_code=A-10-1496-4&slc_lang=en&sid=1 Azza Dawoud azzadawoudhussien@gmail.com 10031947532846005626 0009-0004-9847-8148 Yes Assistant professor at Medicinal and Aromatic Plants & Traditional Medicine Research Institute, National Center of Research, Sudan. Mohammed Abdalbagi 10031947532846005627 10031947532846005627 No Medicinal and Aromatic Plants & Traditional Medicine Research Institute, National Center of Research, Sudan