fa <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><b>Objective</b>: Hypothyroidism occurs when the thyroid gland fails to produce enough hormones, leading to a reduction in metabolism and a slowing down of bodily functions. This condition is typically manageable with medication and is not usually a cause for major concern. The aim of this review study is to identify and report the most important medicinal plants effective in treating hypothyroidism in Iranian traditional medicine.<br> <b>Methodology</b>: In this review, we used keywords such as medicinal plants, hypothyroidism, Iranian traditional medicine, and herbal treatments to search for relevant articles. Databases like Google Scholar, SID, MegaIran, PubMed, and Scopus were used to search and gather reputable scientific articles. Articles and resources related to ethnobotany were reviewed and analyzed for information in this field.<br> <b>Results</b>: The medicinal plants most commonly used for treating hypothyroidism include <i>Zingiber officinale</i> Roscoe, <i>Malus domestica</i> Borkh., <i>Cocos nucifera</i> L., <i>Lens culinaris</i> Medik., <i>Curcuma longa</i> L., <i>Thymus vulgaris</i> L., <i>Cucurbita pepo</i> L., <i>Helianthus annuus</i> L., <i>Prunus dulcis</i> (Mill.) D.A.Webb, <i>Juglans regia</i> L., <i>Cinnamomum verum</i> J. Presl, <i>Allium sativum</i> L., <i>Arctium lappa</i> L., <i>Urtica dioica</i> L., <i>Matricaria chamomilla</i> L., <i>Vaccinium macrocarpon</i> Aiton, <i>Rubus idaeus</i> L., <i>Morus alba</i> L., <i>Morus nigra</i> L., <i>Salvia officinalis</i> L., <i>Aloysia citrodora</i> Pal&aacute;u.<br> <b>Conclusion</b>: The use of medicinal plants in Iranian traditional medicine for the treatment of hypothyroidism highlights the potential of these plants to improve thyroid function and manage related symptoms. Further research and medical consultation are needed to effectively utilize Iran&#39;s native plant flora, so these plants can be used as adjunct therapies alongside standard treatments.</span></span><br> &nbsp;</div> Thyroid gland, Hormone, Hypothyroidism, Medicinal plants, Traditional medicine, Iran 65 73 http://pbp.medilam.ac.ir/browse.php?a_code=A-10-25-65&slc_lang=fa&sid=1 Laya Hooshmand Garehbagh Laya.Hooshmand58@gmail.com 10031947532846005804 10031947532846005804 No Department of Internal Medicine, School of Medicine, Imam Khomeini Hospital, Urmia University of Medical Sciences, Urmia, Iran Somayeh Shahsavari somayeh.shahsavari.pbp@gmail.com 10031947532846005805 10031947532846005805 Yes Research and Science of Tehran, Tehran Branch, Tehran, Iran