en Pharmacognosy كاربردي Review/Systemtic review <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><b>Objective:</b> Abdominal distension is among the most prevalent gastrointestinal disturbances in early infancy, characterized by persistent crying, restlessness, and abdominal discomfort. This condition often arises due to immature gastrointestinal function. In search of safe and natural remedies to alleviate these symptoms, traditional Iranian medicine alongside other complementary medical systems advocates the use of medicinal plants. The present study aims to review and introduce the key herbal remedies commonly employed in traditional medicine for reducing infantile colic.<br> <b>Methods:</b> This review is based on a comprehensive survey and critical analysis of reputable printed and digital sources on Iranian traditional medicine, herbal pharmacopoeias, scientific articles, and electronic databases. The most significant medicinal plants demonstrated to ease abdominal distension were identified, examined, and systematically categorized.<br> <b>Results:</b> According to classical texts and pharmacological references, herbal distillates derived from plants such as <i>Foeniculum vulgare</i> Mill., <i>Thymus vulgaris</i> L., <i>Cuminum cyminum</i> L., <i>Trachyspermum ammi</i> (L.) Sprague, <i>Matricaria chamomilla</i> L., <i>Glycyrrhiza glabra</i> L., <i>Coriandrum sativum</i> L., <i>Melissa officinalis</i> L., <i>Pimpinella anisum</i> L., <i>Apium graveolens</i> L., <i>Rumex acetosa</i> L., <i>Anethum graveolens</i> L., <i>Zingiber officinale</i> Roscoe, <i>Mentha piperita</i> L., <i>Lavandula angustifolia</i> Mill., <i>Olea europaea</i> L., <i>Prunus amygdalus</i> Batsch, <i>Cocos nucifera</i> L., <i>Peganum harmala</i> L. are commonly utilized in gentle stimulation of intestinal peristalsiss to soothe Bloating-related discomfort.<br> <b>Conclusion:</b> The findings underscore the substantial potential of Iranian traditional medicine in managing infantile colic through the use of herbal preparations. When applied thoughtfully and scientifically, these botanicals offer a complementary, safe, cost-effective, and efficacious approach to symptom relief. Nonetheless, it is strongly advised that any oral or topical use of herbal products in infants be supervised by qualified healthcare professionals or traditional medicine practitioners to prevent possible adverse effects.</span></span><br> <br> &nbsp;</div> ,Infantile bloating,medicinal plants,herbal distillates,plant oils,traditional medicine,complementary therapy 9 18 http://pbp.medilam.ac.ir/browse.php?a_code=A-10-1510-1&slc_lang=en&sid=1 Sajad Nourolahi nourollahi1970@gmail.com 10031947532846005565 10031947532846005565 Yes Department of Pediatrics Division of Neonatalog, Ayatollah Taleghani Hospital, Ilam University of Medical Sciences, Ilam, Iran Nasrin Ghiasi nghiasi@ymail.com 10031947532846005566 10031947532846005566 No Department of Midwifery, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran