Plant Biotechnology Persa

en Evaluation the Effects of Medicinal Plants in the Zagros Mountains on the Reproductive System: A Systematic Review Herbal Drugs كاربردي Review/Systemtic review <div style="text-align: justify;">Objective: Infertility is a global challenge for couples and may arise from various factors. Studies have highlighted a link between oxidative stress and infertility, emphasizing the role of antioxidants in mitigating reproductive damage. Certain medicinal plants with antioxidant properties have traditionally been used for this purpose. This review focuses on the effects of Pistacia atlantica, Capparis spinosa, Matricaria chamomilla L., and Ferulago angulata, commonly found in Iran’s Zagros Mountains, on the reproductive system. This study systematically reviewed research on the effects of Zagros-native plant species on infertility, analyzing findings from multiple scientific databases using qualitative methods. Methods: Indexed searches were conducted in Persian and English using the terms ((“Fertility” OR “Reproductive System” OR “Testis” OR “Oocyte” OR “Sexual hormone” OR “LH” OR “FSH” OR “Testosterone” OR “Semen”) AND (“Zagros Mountains” OR “Pistacia atlantica” OR “Baneh” OR “Matricaria chamomilla” OR “Chamomile” OR “Capparis spinosa” OR “Caper” OR “Legji” OR “Ferulago angulata” OR “Chavir”)) from 2000 to 29 December 2024 in PubMed, Scopus, ScienceDirect, Google Scholar, SID, and Magiran. Out of 342 initially screened articles, 51 were relevant, and 17 fully matched the inclusion criteria for detailed analysis. Results: Most studies reviewed indicate positive effects of these plants on infertility-related parameters. However, a limited number of reports describe adverse effects at certain dosages. Conclusion: Various extracts of these medicinal plants can enhance fertility by promoting healthy gamete production. Careful removal of unnecessary or toxic compounds, adherence to proper extraction methods, and appropriate dosing are essential to minimize potential side effects <img alt="" src="./files/site1/images/copuediting.png" style="width: 586px; height: 265px;" >  </div> ,Pistacia atlantica,Capparis Spinosa L,Matricaria Chamomilla,Ferulago Angulata,Antioxidant,Infertility 185 198 http://pbp.medilam.ac.ir/browse.php?a_code=A-10-1519-1&slc_lang=en&sid=1 Amirabbas Gharibi amirabbasgharibi3707@gmail.com 10031947532846006290 0009-0001-6388-9906 No Student Research Committee, Ilam University of Medical Sciences, Ilam, Iran Firoozeh Niazvand niazvandf@gmail.com 10031947532846006291 10031947532846006291 Yes Department of Anatomical Sciences, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran Mahtab Teimouri teimouri.mahtab1986@gmail.com 10031947532846006292 10031947532846006292 No Department of Anatomical Sciences, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran. Ali Aidy Aliaidi11@yahoo.com 10031947532846006293 10031947532846006293 No Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran