en پژوهشي Research <em>Glycyrrhiza glabra</em> L. is a valuable medicinal and nutritional plant of the Fabaceae family. In traditional medicine, it is used to treat duodenal ulcers, coughs, sore throats, inflammation, bloating, strong laxatives and antidotes, hot flashes, relieves thirst, relieves skin discomfort, and anti-allergies. The most important active ingredient in this plant is glycyrrhizic acid.<em> G. glabra</em> L. is a widely used plant in Iran and medicinal products have been produced from it in Iran. Interactions between herbal and chemical drugs are also common. In this review study, drug interactions between <em>G. glabra</em> L. and chemical corticosteroid drugs were investigated and reported. <em>G. glabra</em> L. &nbsp;can interact with a variety of chemical drugs, so concomitant use of <em>G. glabra</em> L. with other drugs requires caution. Medicinal plant, Glycyrrhiza glabra L., Drug interaction 28 30 http://pbp.medilam.ac.ir/browse.php?a_code=A-10-82-2&slc_lang=en&sid=1 Pegah Shahkib shakib.pegah@yahoo.com 10031947532846001060 10031947532846001060 No Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran Mahmoud Bahmani mahmood.bahmani@gmail.com 10031947532846001061 10031947532846001061 Yes Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran Pouya Parsaee 10031947532846001062 10031947532846001062 No Research Center of Nutrition and Organic Products, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran