@article{ author = {Karami, Nima and Karimi, Mohammad and Bahmani, Mahmou}, title = {Constipation: An ethno-botanical study of medicinal plants used for constipation in Shahrekord city, Chaharmahal & Bakhtiari province, Iran}, abstract ={Constipation is a common gastrointestinal problem in society, both in children and in adults, which imposes stupendous costs on society. For centuries, people have used medicinal plants, herbal teas, and teas to relieve digestive problems, including to stimulate the digestive system and reduce constipation. Therefore, in this study we sought to investigate the indigenous and ethnobotanical knowledge regarding constipation in children and infants in Shahrekord. The present ethnobotanical study was carried out through a questionnaire in Shahrekord. This study was conducted from April 2017 to February 2018 through face-to-face interviews and a questionnaire among 29 traditional therapists. The results of this study showed that medicinal plants such as Descurainia sophia (L.) Prantle., Rumex pulcher L., Alyssum spp.Stead. Ex Boiss., Prunus amygdalus L., Astragalus adscendens Bioss. & Hausskn, Echinops persicus Stev. & Fisch., Plantago major L., Rheum ribes L., Stachys lavandulifolia, Plantago major, Alcea spp., Glycyrrhiza glabra L., Peganum harmala L., Pistachia atlanta Desf. and Prangos ferulacea L. are traditionally used to treat constipation in children and infants  }, Keywords = {,Gastrointestinal diseases,Constipation,Iran}, volume = {2}, Number = {1}, pages = {1-7}, publisher = {}, doi = {10.29252/pbp.2.1.1}, url = {http://pbp.medilam.ac.ir/article-1-42-en.html}, eprint = {http://pbp.medilam.ac.ir/article-1-42-en.pdf}, journal = {Plant Biotechnology Persa}, issn = {2676-7414}, eissn = {2676-7414}, year = {2020} } @article{ author = {Mahmoud, Bahmani and Hadavi, Marzieh and Abbasi, Naser}, title = {Study of extraction and chemical compounds of Scrophularia striata Boiss. and Scrophularia deserti Delile using HS-SPME and GC-MS}, abstract ={In this study, from June 2019 to May 2019 aerial parts of Scrophularia striata Boiss. were collected from Ilam city and those of Scrophularia deserti Delile from Dehloran city, Ilam province in western Iran. The aerial parts of the medicinal plants were pulverized. The essential and volatile oils were extracted by headspace solid-phase microextraction (HS-SPME) and their chemical compounds analyzed by Gas chromatography–mass spectrometry (GC-MS). Using HS-SPME, 68 and 49 chemical compounds were identified from S. striata and S. deserti, respectively. Spathulenol (18.41%) was the highest chemical compound of the essential oil of S. striata, followed by caryophyllene oxide (15.38%), linalool (11.85%), alpha-terpineol (8.34%), trans-caryophyllene (4.44%) and geraniol (3.10%). The most important identified compounds from S. deserti were caryophyllene oxide (15.38%), linalool (11.85%), alpha-terpineol (8.34%), trans-caryophyllene (4.44%) and geraniol (3.10%). The most important chemical compounds of S. deserti essential oil included alpha-pinene (25.54%), alpha-phellandrene (19.60%), beta-myrcene (11.29%) and trans-caryophyllene (6.78%). Results show major constituents of this two plant include with a high amount of Spathulenol and caryophyllene oxide has high pharmaceutical and healthful value.}, Keywords = {Scrophularia striata Boiss., Scrophularia deserti Delile, Essential oil, HS-SPME, GC-MS}, volume = {2}, Number = {1}, pages = {8-13}, publisher = {}, doi = {10.29252/pbp.2.1.8}, url = {http://pbp.medilam.ac.ir/article-1-50-en.html}, eprint = {http://pbp.medilam.ac.ir/article-1-50-en.pdf}, journal = {Plant Biotechnology Persa}, issn = {2676-7414}, eissn = {2676-7414}, year = {2020} } @article{ author = {Sadighara, Paris}, title = {A new ferric iron reducing assay for evaluation total antioxidant activity of food and biological samples}, abstract ={Various methods have been developed in recent years to evaluate the total antioxidant activity of food and biological samples. In this study, a new ferric iron reducing assay was applied for measuring total antioxidants. This method is based on the oxidation on the reducing the iron III to iron II. The extraction was incubated with Fecl3 and KSCN. Ferric thiocyanate complex is formed in an acid solution. This complex is measured at 474 nm. A lower absorbance indicates increased reducing power.}, Keywords = {Antioxidant activity, Food and biological samples, Oxidative stress}, volume = {2}, Number = {1}, pages = {14-15}, publisher = {}, doi = {10.29252/pbp.2.1.14}, url = {http://pbp.medilam.ac.ir/article-1-44-en.html}, eprint = {http://pbp.medilam.ac.ir/article-1-44-en.pdf}, journal = {Plant Biotechnology Persa}, issn = {2676-7414}, eissn = {2676-7414}, year = {2020} } @article{ author = {MerbiekSabzevari, Zohreh and Goodarzi, Gholamreza and Zinatifar, Saba and Anbari, Khatereh and Hassani, Maryam and Shakib, Pegah}, title = {Prevalence of Ethiological Factors and Bacterial Sensitivity pattern of Urinary Infection in First and Secondary Graduate Students in Khorramabad City, Iran}, abstract ={Urinary tract infection (UTI) is one of the most common bacterial infections in childhood that delayed diagnosis and treatment can cause irreversible complications. The aim of this study was to determine the prevalence of urinary tract infection in elementary school children in Khorramabad city, Iran. In this descriptive cross-sectional study, 460 female students of elementary and secondary schools of Khorramabad city were recruited after completing a questionnaire including symptoms of infection, medical and disease history, and urine culture. Antibiotic susceptibility pattern was determined by disk diffusion method accordance with Clinical and Laboratory Standards Institute (CLSI) instructions. Statistical analysis were performed by SPSS software. Of 460 students, based on urine culture results 12 (2.6%) had urinary tract infection. Asymptomatic bacteriuria in 5 patients (1.1%) and positive culture and clinical symptoms were reported in 7 cases (1.5%). Escherichia coli (83.3%) was reported as the main cause of UTI among the tested samples. The highest antibiotic susceptibility was related to imipenem (91.6%) and ceftazidime (83.3%). The prevalence of UTI, pathogenic microbial agents and sensitivity to antibiotics in different regions and periods has a significant difference, which can be due to different health levels, constant change in incidence of germs that cause UTI and various antibiotics resistance. Because almost half of the cases of urinary tract infection are asymptomatic, screening for primary school children is necessary.}, Keywords = {Prevalence, Urinary Tract Infection (UTI), Disk diffusion method, Antibiotic sensitivity, Escherichia coli}, volume = {2}, Number = {1}, pages = {16-20}, publisher = {}, doi = {10.29252/pbp.2.1.16}, url = {http://pbp.medilam.ac.ir/article-1-43-en.html}, eprint = {http://pbp.medilam.ac.ir/article-1-43-en.pdf}, journal = {Plant Biotechnology Persa}, issn = {2676-7414}, eissn = {2676-7414}, year = {2020} } @article{ author = {Gholami-Ahangaran, Majid and Ahmadi-Dastgerdi, Asiye and Karimi-Dehkordi, Maryam}, title = {Thymol and carvacrol; as antibiotic alternative in green healthy poultry production}, abstract ={Thymol and carvacrol as a natural essential oils and phenol compounds, are a component derived from some medicinal plants, such as thyme and oregano species. These compounds have been shown to possess a wide range of biological activities, including antimicrobial, antioxidant, anti-infalmmatory, modulating of immunity respond and anticarcinogenic properties. One of main effects of these compounds that make them as valuable material in poultry medicine is antibacterial effect. The increasing consumption of organic and healthy meat and eggs in human society has made it increasingly necessary to use compounds that are completely natural and do not cause problems for human health. Since antibiotics are chemical compounds that can remain in meat and eggs and cause antibiotic resistance, allergies, mutations and even poisoning in humans. Therefore, utilization of compounds that are natural antibiotics can be easily fed with a higher safety in healthy poultry production. In this regard, the role of thymol and carvacrol as natural antibiotics in the poultry production has been discussed in a recent review.}, Keywords = {Antibacterial,Carvacrol,Thymol,Poultry.}, volume = {2}, Number = {1}, pages = {22-25}, publisher = {}, doi = {10.29252/pbp.2.1.22}, url = {http://pbp.medilam.ac.ir/article-1-48-en.html}, eprint = {http://pbp.medilam.ac.ir/article-1-48-en.pdf}, journal = {Plant Biotechnology Persa}, issn = {2676-7414}, eissn = {2676-7414}, year = {2020} } @article{ author = {Khadem, Erfan and Nafari, Amir Hossein and Safarzadeh, Ali and FalavandJozaei, Reza and Almasian, Mohammad and Elyasi, Hossei}, title = {The role of bacteria in the treatment of cancer: A comprehensive review}, abstract ={Cancer is an important public health issue worldwide and is the main cause of death in the developed countries and the second cause of death in the developing countries. There are several treatments for cancer such as photodynamic therapy, surgery, chemotherapy, hormonal therapy, radiotherapy and immunotherapy. Current cancer treatments have various side effects, including the gradual resistance of cancer cells to treatment. The era of targeted cancer therapy has brought about new clinical approaches such as antibodies, small molecules, antiangiogenics, and antivirals. Yet even these strategies remain limited in their ability to accumulate in tumors and tumor penetration, which are the main obstacles in the treatment of cancer. Historic efforts to harness living organisms to fight cancer have recently been revived in the field of synthetic biology. Certain circulating bacteria can intrinsically home in on tumors, and can be engineered to controllably induce local cytotoxicity while remaining unobtrusive to the host system. Due to the ineffectiveness of conventional treatments such as chemotherapy and radiation therapy in advanced tumor stages, resistance to treatment and non-specificity of these treatments, with the advancement of studies in this field, it is hoped that bacterial therapy will add a new dimension to cancer treatment.}, Keywords = {Cancer, Bacterial therapy, Toxin, Gene vector, Hypoxia}, volume = {2}, Number = {1}, pages = {26-34}, publisher = {}, doi = {10.29252/pbp.2.1.26}, url = {http://pbp.medilam.ac.ir/article-1-47-en.html}, eprint = {http://pbp.medilam.ac.ir/article-1-47-en.pdf}, journal = {Plant Biotechnology Persa}, issn = {2676-7414}, eissn = {2676-7414}, year = {2020} } @article{ author = {Elyasi, Hossein and Rahimi, Hadis and Sepahvend, Asghar}, title = {Gelatin: advantages and disadvantages of gelatin from plant and animal sources}, abstract ={Gelatin is a solid and transparent material that has wide application in various industries, especially for the production of food and pharmaceutical. This material is mainly made from meat, skin and bones of pigs and cows around the world. The industrial process of gelatin production is a long and costly process. It seems; these sources of gelatin production may be harmful to health. Therefore, this study was aimed at reviewing the alternative sources of gelatin production and the disadvantages and benefits of each of them. Relevant articles were searched from Google Scholar, Pub Med, Scopus, Science direct, and Cochrane library. According to the results of this article, gelatin with a source of animal can have many harmful effects on human health. While it is possible to produce good and useful gelatin using plant sources. Nowadays, from materials such as agar, pectin, carrageenan and konjac that are mentioned above, and as well as other materials, very good gelatins are prepared. And further researches are needed to find the rich sources of good gelatins or to find plants that have appropriate gelatin. In total, in gelatin, there are 18 types of amino acids, and of 10 amino acids needed for the body, 9 are in gelatin. In total, gelatin is introduced safe by the FDA. Note: This article has been revised and rewritten due to the request of the corresponding author from the journal "Plant Biotechnology Persa" due to the use of unreferenced contents. In October 2023, the journal " Plant Biotechnology Persa " accepted the revised version of article following the COPE rules. Formerly title of paper: Gelatin, halal or haram?.  }, Keywords = {Gelatin, Medicine, Medicinal herbs, Traditional medicine}, volume = {2}, Number = {1}, pages = {35-41}, publisher = {}, doi = {10.29252/pbp.2.1.35}, url = {http://pbp.medilam.ac.ir/article-1-45-en.html}, eprint = {http://pbp.medilam.ac.ir/article-1-45-en.pdf}, journal = {Plant Biotechnology Persa}, issn = {2676-7414}, eissn = {2676-7414}, year = {2020} } @article{ author = {Abassi, Naser and Ghaneialvar, Hori and Shahsavari, Somayeh}, title = {Natural remedies effective on stomachache in traditional medicine}, abstract ={Stomach ache is one of the most chronic and debilitating abdominal pains. Medicinal plants are one of the most accessible sources for treating diseases like gastrointestinal disorders. In this review, we investigate and report the most important medicinal plants recommended by Persian medicine for treating stomach aches and comparing them with their proven effects in modern medicine. Methods: Gastric pain was probed in Persian medicine reliable textbooks such as Cannon of Medicine (Ibn Sina), Tibbe-Akbari (Muhammad Akbar  Arzaani ), The Complete Art of Medicine (Kitāb Kāmil as-Sinā’a at-Ṭibbiyya) (Haly Abbas), Explanation of insults and signs (Kermani) Tohfeh Al-Mo'menin (Seyed Mohammad Momen Tonekaboni), and some notes were taken. Results: The results showed that Panicum miliaceum, Punica granatum, Solanum nigrum, Calicotome spinosa, Tamarindus indica, Cuminum cyminum, Prunus domestica, Matricaria recutita, Viola odorata, Plantago psyllium, Berberis vulgaris, Pyrus  communis, Linum usitatissimum, Vitis vinifera were the most important plant sources used in treating the stomach ache according to Persian medicine. Conclusion: The findings of this study showed that the useful effects of many recommended plants in Persian medicine are confirmed by recent scientific researches and are reliable.}, Keywords = {,Pain,Medicinal plants,Gastrointestinal disorders,Persian medicine}, volume = {2}, Number = {1}, pages = {42-47}, publisher = {}, doi = {10.29252/pbp.2.1.42}, url = {http://pbp.medilam.ac.ir/article-1-37-en.html}, eprint = {http://pbp.medilam.ac.ir/article-1-37-en.pdf}, journal = {Plant Biotechnology Persa}, issn = {2676-7414}, eissn = {2676-7414}, year = {2020} } @article{ author = {Elyasi, Hossein and Rahimi, Hadis and Nafari, Amirhossei}, title = {Effects of Genetically Modified corn on human health}, abstract ={Genetic modification is a specific part of gene technology that changes the genetic structure of living organisms, such as animals, plants, or microorganisms. Genetically Modified, is known with such names as Transgenic or Transgenic. In recent years, discussions have arisen about the potential effects of transgenic corn on health There are also discussions about its effect on other insects and other plants due to the gene flow The study was conducted as a systematic double-blind review by searching the Internet at the Google Scholar, PubMed, Science Direct, Medline, Highwire, MD Consult and Scopus databases. From the result of this study, we can come to a Conclusion that any transgenic product is not usable and can have many disadvantages, while some of them are completely safe and usable.}, Keywords = {Genetically Modified corn, genetic modification, recombinant DNA}, volume = {2}, Number = {1}, pages = {48-54}, publisher = {}, doi = {10.29252/pbp.2.1.48}, url = {http://pbp.medilam.ac.ir/article-1-46-en.html}, eprint = {http://pbp.medilam.ac.ir/article-1-46-en.pdf}, journal = {Plant Biotechnology Persa}, issn = {2676-7414}, eissn = {2676-7414}, year = {2020} } @article{ author = {shakib, pegah and rouhi, samaneh and mrzolfaghary, mohammad rez}, title = {The role of probiotics in preventing dental caries}, abstract ={Tooth decay has occurred due to the numerous microorganisms in the mouth such as Streptococcus and Lactobacilli bacteria that can produce acid. Commercial antiplatelet agents are predominantly antibacterial compounds, but these compounds can disrupt oral bacterial flora and induce and enhance the growth of opportunistic pathogens, including Candida albicans. Nowadays, bacterial therapy is a replacement therapy for microorganisms. One of the methods of bacterial therapy is the use of probiotic bacteria. So far, many studies have been done on the effect of probiotic-containing food products on the microbial factors of tooth decay. Therefore, this study aimed to investigate the effect of probiotics on dental caries. The search queries were from ISI, PubMed, Scopus, Science Direct, magiran, SID databases. Key words were probiotic, dental caries, bacterial caries, tooth decay, laboratory and clinical studies. Finally, the selected articles were used for the review table. The results of the review of studies showed that probiotic strains are able to control bacterial agents that cause dental caries.  }, Keywords = {,Oral diseases,Dental,Dental caries,Probiotics}, volume = {2}, Number = {1}, pages = {55-58}, publisher = {}, doi = {10.29252/pbp.2.1.55}, url = {http://pbp.medilam.ac.ir/article-1-40-en.html}, eprint = {http://pbp.medilam.ac.ir/article-1-40-en.pdf}, journal = {Plant Biotechnology Persa}, issn = {2676-7414}, eissn = {2676-7414}, year = {2020} } @article{ author = {Eftekhari, Zohre}, title = {Antimicrobial properties of medicinal plants; The new therapeutic aspect of Valeriana officinalis}, abstract ={The increased use of antibiotics and chemicals with various side effects is now persuading scientists to develop natural substitutes with appropriate effectiveness and protection for humans. The outbreak of the world's emerging and re-emerging infectious diseases has prompted pharmaceutical companies to develop new medicines. Valerian is one of the worldwide recognized medicinal herbs that consume abundantly for the treatment of various human diseases and disorders. The Valerianaceae family contains 10 genera and approximately 300 species 1.  It has widely cultivated for commercial purposes in some regions of Iran, including ornamental, edible, and medical1.  V.officinalis rhizomes contain two major constituent groups, including volatile oil sesquiterpens and valpotriates. Both active components are present in the hypodermis in large thin-cells at the roots, and rhizomes periphery2. Although there are still some disagreements about the relative efficacy of various groups of V.officinalis compounds, it is widely accepted that valerenic acid is the most important biologically active component3,4. Valerenic acid and its derivatives are commonly considered to contribute to valerian extracts ' pharmaceutical effect, characterized and isolated by different analytical methods5. Valerenic acid can be used in different disorders such as depression, chronic anxiety, and sleep disorders on the basis of the previous studies4. Based on previous literature, the valerenic acid component had antimicrobial effects on different microorganisms such as Helicobacter pylori, Staphylococcus aureus, and Candida albicans and its methanolic extract functions were dose-dependent6,7,8. Since the antimicrobial activity of V. officinalis in the total extract was correlated with abundant monoterpenoids and sesquiterpenoids, more research on various aspects of pharmaceutical effects is suggested.  }, Keywords = {,Antimicrobial,Valeriana officinalis,New aspect}, volume = {2}, Number = {1}, pages = {59-60}, publisher = {}, doi = {10.29252/pbp.2.1.59}, url = {http://pbp.medilam.ac.ir/article-1-39-en.html}, eprint = {http://pbp.medilam.ac.ir/article-1-39-en.pdf}, journal = {Plant Biotechnology Persa}, issn = {2676-7414}, eissn = {2676-7414}, year = {2020} } @article{ author = {Karimi, Elahe}, title = {Alzheimer\'s: Phytotherapy and the most important herbs in the treatment of Alzheimer\'s}, abstract ={Alzheimer's disease is a progressive form of dementia that causes problems with memory, thinking, and behavior. This disease is associated with profound effects on intelligence, self-care, speech impairment, and dysfunction, motor functional and cognitive impairment. This letter discusses some of the most important herbal plants used for Alzheimer's disease. Herbs such as Petroselinum crispum, Thymus vulgaris, Hypericum perforatum, Matricaria chamomilla, Salvia officinalis, Allium sativum, Ziziphus jujube, Lavandula officinalis, Curcuma longa, Salvia Rosmarinus and Cyperus rotundus are considered to treat Alzheimer's. Medicinal herbs can be used in the treatment of Alzheimer's and they can be produced in the future as effective natural anti-Alzheimer's drugs.  }, Keywords = {Alzheimer, Disease, Disorder, Medicinal plants}, volume = {2}, Number = {1}, pages = {61-62}, publisher = {}, doi = {10.29252/pbp.2.1.61}, url = {http://pbp.medilam.ac.ir/article-1-36-en.html}, eprint = {http://pbp.medilam.ac.ir/article-1-36-en.pdf}, journal = {Plant Biotechnology Persa}, issn = {2676-7414}, eissn = {2676-7414}, year = {2020} }