@article{ 
author = {Samadi, Naser and Motarjemizadeh, Ghader and Moharmzadeh, Nasim},  
title = {Therapeutic Effects of Low Dose Acetylsalicylic Acid on Acute Central Serous Chorioretinopathy: A Prospective, Interventional, Single Centre Case Series}, 
abstract ={Objective: Central serous chorioretinopathy (CSCR) is a common cause of central vision loss, predominantly affecting men between 20 and 60 years of age. This study aimed to evaluate the efficacy of low-dose aspirin in the treatment of acute CSCR. Methods: A total of 60 patients (60 eyes) with a history of acute CSCR while on fenofibrate therapy were randomized into two groups. Group A received aspirin 100 mg orally once daily for 1 month, followed by 100 mg every other day for 5 months. Group B received no medication and served as the control group. Best-corrected visual acuity (BCVA), mean subretinal fluid vertical diameter (SFVD), optical coherence tomography (OCT), and central macular thickness (CMT) were assessed at baseline and during follow-up visits at 1 week, and at 1, 2, 3, and 6 months. Results: There were no significant differences between the two groups at baseline in terms of BCVA (P = 0.968) or SFVD (P = 0.774). Group A demonstrated significant improvement in BCVA and a significant reduction in SFVD at all follow-up intervals compared with baseline values. Compared with the control group, aspirin treatment resulted in a statistically significant improvement in BCVA (P < 0.001) and a reduction in SFVD (P < 0.001) after 6 months. Moreover, 93.3% (n = 28) of patients in Group A experienced no recurrences during the follow-up period, whereas only 60.0% (n = 18) of patients in Group B achieved complete resolution of CSCR without recurrence. Conclusion: Patients treated with low-dose aspirin experienced faster visual recovery and fewer recurrences compared with untreated patients. These findings suggest that oral aspirin may be a promising therapeutic option for selected patients with acute CSCR.},  
Keywords = {,central serous chorioretinopathy,aspirin,acetyl salicylic acid,best corrected visual acuity (BCVA),recurrence},
volume = {6},
Number = {1}, 
pages = {1-9}, 
publisher = {},

doi = {10.61186/pbp.6.1.1},
url = {http://pbp.medilam.ac.ir/article-1-214-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-214-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Amrollahi-Sharifabadi, Mohammad and RezaeiOrimi, Jamal and Kamalpour, Mohamm},  
title = {Science of Toxicology in Rabban Al-Tabari’s Paradise of Wisdom: A Review}, 
abstract ={As an important threat throughout history, poisonings have plagued mankind from ancient times to today. This review intended to answer the question that whether toxicology and intoxications have been addressed in the one of the oldest medical texts of traditional Persian medicine; Al-Tabari’s Paradise of Wisdom and whether there had been a specific approach to manage poisonings. Extensive research was conducted in Al-Tabari’s book Firdausu’l-Ḥikmat also known as Paradise of Wisdom using toxicology related keywords. Moreover, current literature was searched with relevant keywords using Web of Science, Science Direct, Embase, PubMed, Google Scholar, MagIran, IranMedex, and SID to adapt the data with modern toxicological knowledge. Our result revealed that Al-Tabari described the toxicity and pertinent treatments for Nerium oleander L, Papaver somniferum L, Aconitum ferox Wall, Euphorbia serrata, Anamirta paniculata, Semecarpus Anacardium, Brassica oleracea, Coriandrum sativum, Hyoscyamus albus, and Colchicum autumnale L. He indicated the toxicity of the winds that blowing from areas with toxic pollen and scent of plants. Also, he mentioned the toxicity of snakes, scorpions, spiders, bees, and rabid animals as well as the hazardous creatures including Mus musculus and Lytta vesicatoria along with some descriptions for related treatments. At the end, Al-Tabari reckoned the toxicology and treatments of some toxic minerals including mercury, iron, and lead. Conclusively, Al-Tabari contributed to toxicological sciences though dedicating a proportion of his book Paradise of Wisdom to the subject of toxicants and poisoning therapeutics. Further studies are recommenced to divulge toxicological science in historical sources including traditional medical works.},  
Keywords = {,Toxicology,History,Persian Traditional Medicine,Medieval,Poisoning},
volume = {6},
Number = {1}, 
pages = {10-19}, 
publisher = {},

doi = {10.61186/pbp.6.1.10},
url = {http://pbp.medilam.ac.ir/article-1-210-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-210-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Motargemizadeh, Ghader and Samadi, Naser and Khadem, Nazani},  
title = {A comparative Study on Surgical Outcomes in Primary Pterygium Excision Using Argon Laser Therapy Versus Bare Sclera Technique: A Randomized Prospective Trial}, 
abstract ={Objective: The frequency of recurrence is a critical factor in the utilization of different treatments for pterygium. The present study was undertaken to compare the pterygium recurrence rates after bare sclera excision with that of argon laser therapy. Methods: Sixty eyes of 53 patients with primary pterygium were included in this prospective, interventional case series. The participants were randomly categorized into 2 groups each consisting of 30 subjects. In the first group, pterygium excision was performed using bare sclera technique whereas the second group received argon laser therapy alone. The patients were examined for pterygium recurrence and complications at postoperative 1 and 7 days as well as in months 1, 3, and 6 after the operation. All analyses were performed using SPSS software (version 17.0) and P-values less than 0.05 were considered significant. Results: Pterygia recurred in 7 eyes (23.3 %) in the first group (i.e. bare sclera group) and in 4 eyes (13.3 %) in the second group (i.e. argon laser therapy group). The recurrence rate was not significantly different between the two groups. No ocular or systemic complication developed till the end of follow-up. Conclusion:  Argon laser photocoagulation of pterygium may be more favorable for patients with coagulopathy or a history of conjunctival surgery. The coagulation effect of the argon laser may prevent severe conjunctival bleeding, which may occur after surgical excision in patients with coagulopathy.},  
Keywords = {,Pterygium,Sclera,laser therapy,recurrence},
volume = {6},
Number = {1}, 
pages = {20-27}, 
publisher = {},

doi = {10.61186/pbp.6.1.20},
url = {http://pbp.medilam.ac.ir/article-1-213-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-213-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Asadzadeh, Reza and Karimi, Elahe},  
title = {Exploring Potassium in Tomatoes and cucumis melo through Atomic Absorption Spectroscopy: A Scientific Insight}, 
abstract ={Objective: Among the numerous plant mineral supplements, potassium (K) projects as a cation showing the most grounded impact on quality properties that discourage- mine natural product attractiveness, customer inclination, and the concentration of fundamentally imperative human-health related phytonutrients. Be that as it may, numerous plant, soil, and natural variables frequently restrain satisfactory take-up of K from the soil in adequate sums to fulfill natural product K necessities amid advancement to optimize the previously mentioned quality traits.  Methods: In this study, the atomic absorption method was used to check the total amount of potassium in tomatoes and melons. First, the plant sample was collected in spring (2021-2022) in Ilam city and dried in the shade, then it was prepared and the amount of potassium was measured by an atomic absorption device. Results: The results showed that the amount of potassium in tomatoes and Cucumis melo were about 330 and 352 mg/100gr, respectively. Conclusion: Atomic Absorption Spectroscopy opens a scientific window into the potassium content of tomatoes and Cucumis melo, offering precise measurements and valuable insights. By bridging the gap between scientific analysis and nutritional awareness, this exploration enhances our appreciation for tomatoes and Cucumis melo not only a culinary delight but also a rich source of essential minerals.  },  
Keywords = {,Potassium,Tomatoes,Cucumis melo,Atomic Absorption Spectroscopy,Plant mineral nutrients},
volume = {6},
Number = {1}, 
pages = {28-31}, 
publisher = {},

doi = {10.61186/pbp.6.1.28},
url = {http://pbp.medilam.ac.ir/article-1-220-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-220-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {babakhani, Mona and khaleghi, sepideh and hajrasouliha, shadi},  
title = {Investigating the Antioxidant and Antimicrobial Properties of Silver Nanoparticles Synthesized Using the Alcoholic Extract of Spirulina subsalsa Algae}, 
abstract ={Objective: Silver nanoparticles (AgNPs) are valuable commercial nanomaterials due to their unique biological properties. As bacteria become more resistant to synthetic antibiotics, exploring natural alternatives such as essential oils, plant extracts, and mineral substances has become essential. Algae, which are diverse and widespread, are noteworthy for their antibacterial and antioxidant properties. This study focused on creating AgNPs using Spirulina algae alcoholic extract and examining their antibacterial and antioxidant properties. Materials and Methods: AgNPs were synthesized by the green method and evaluated by Fourier Transform Infrared Spectroscopy (FT-IR), Dynamic Light Scattering (DLS), and Transmission Electron Microscopy) TEM(. The green synthesis was evaluated at 400-450 nm using a spectrophotometer. Then, the total phenol and flavonoid content of AgNPs were measured. The Diphenyl Picryhydrazyl (DPPH) test was used to evaluate the antioxidant properties. The antimicrobial activity of nanoparticles against Staphylococcus aureus and Pseudomonas aeruginosa was investigated by Minimum Inhibitory Concenteration (MIC) and Minimum Bacteriocidal Concentration (MBC) tests. Results: The FT-IR results demonstrate the successful synthesis of AgNPs with unique covalent bonding. DLS analysis also confirms spherical nanoparticle morphology and uniform 15-20 nm distribution. In MIC/MBC results, the antibacterial effect of AgNPs was observed within the first few hours (1 to 5 hours), reaching its peak at 24, 48, and 72 hours. Nanoparticles significantly inhibited the growth and survival of both gram-positive and Gram-negative bacteria. Conclusion: Green-synthesized AgNPs have antibacterial effects in addition to antioxidant capabilities. As they can kill both gram-positive and gram-negative bacteria, these nanoparticles might be a great alternative to conventional antibiotics.  },  
Keywords = {Antibacterial agents,Antioxidants,Biosynthesis,Metal nanoparticle,Spirulina},
volume = {6},
Number = {1}, 
pages = {32-42}, 
publisher = {},

doi = {10.61186/pbp.6.1.32},
url = {http://pbp.medilam.ac.ir/article-1-218-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-218-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Akbari, Reza and azarifam, safa and kouhkan, mehri},  
title = {Evaluation of Antibacterial Effects of Newly Synthesized Derivative Methyl 2\'-Methyl-1,3-Dioxo-1,1\',2\',3,5\',6\',7\',7a\'-Octahydrospiro[Indene-2,3\'-Pyrrolizidine]-2\' Carboxylate against Staphylococus Aureus and Escherichia Coli.}, 
abstract ={Objective: Unfortunately, infectious diseases are still one of the most important health problems around the world. The resistance of pathogenic bacteria to several drugs is an important and growing problem in the treatment of infectious diseases and hospital infections. It seems necessary to identify new compounds that have inhibitory or lethal effects on this bacterium. That's why we decided antimicrobial efficacy. The newly synthesized compound (2-methyl-1,3-dioxo-',11',2',3',5',6',7'a,7-octahydrospiro] inden-'2,3-pyrrolizidine 2-carboxylate (5) on Staphylococcus aureus and Escherichia coli bacteria. Methods: At first, synthesized of methyl'2-methyl-1,3-dioxo-1',1',2',3',5',6', 7',7'a, -octahydrospiro] inden-'2,3-pyrrolizidine 2- Carboxylate was prepared by green chemistry method and with the help of microwave in one pot. Microbial culture media containing control bacteria of Staphylococcus aureus and Escherichia coli were prepared and concentrations of 70 to 110 Landa of the above compound were added to the samples. The antimicrobial property of the samples was determined after 3 days using the disk diffusion method and broth micro dilution method was determined, as well as the minimum inhibitory concentration and bacterial lethality of the samples. Results: The minimum inhibitory concentration and bacterial lethality in the above combination against the same standard strain of Escherichia coli bacteria was obtained at the rate of 12.5 μg/mL. The minimum inhibitory and lethal concentration of methyl methacrylate compound against the standard strain of Staphylococcus aureus bacteria was 12.5 and 25 μg/mL, respectively. Conclusion: The use of the above combination was effective in controlling and inhibiting the tested bacteria.  },  
Keywords = {,Pyrrolizidine,Staphylococcus aureus and Escherichia coli},
volume = {6},
Number = {1}, 
pages = {43-48}, 
publisher = {},

doi = {10.61186/pbp.6.1.43},
url = {http://pbp.medilam.ac.ir/article-1-212-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-212-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Amrollahi-Sharifabadi, Mohammad and Kamalpour, Mohammad and RezaeiOrimi, Jamal and Aghabeiglooei, Zahra and alimi-Sabour, Ebrahim S and Abdelaziz, Sahar},  
title = {Potential Usage of Ruta graveolens L. in Ophthalmology}, 
abstract ={Objective: There has been growing interest in medicinal plants due to their therapeutic properties in safe lower doses, despite their unpleasant smell, bitter taste, and toxicity in higher doses. Ruta graveolens L., commonly known as the herb of grace, common rue, rue, ruda, sodab, fijen, and al-suzab is a potential therapeutic candidate with variable healing properties and traditional uses. One of its lesser-known uses is in the treatment of eye conditions. The current study aimed to investigate the ophthalmological potential of Ruta graveolens L. using available scientific literature. Methods: To this end, we extensively searched Scopus, Science Direct, Web of Science, Embase, PubMed, Google Scholar, IranMedex, SID, and Magiran for related literature on the cultural, historical and scientific aspects of Ruta graveolens L. and ophthalmology. Also, traditional Persian medicine books including Al-Qanun Fi Al-Tibb, Al-Hawi Fi Al-Tibb, Al-Abniya, and Ikhtiyarat Badiei thoroughly searched to find the potential application of rue in ophthalmology. Results:  Our historical, literary, and traditional medicine data revealed that R. graveolens L. used in the ophthalmic field probably due to its beneficial effects in the past. Also, there are some modern studies elucidated the beneficial effects of this plant in ophthalmology. Conclusion:  This study suggests that R. graveolens L. plant can be a promising ophthalmic drug due to its specific ocular benefits warranting further research with modern technologies.  },  
Keywords = {Integrative Medicine,Medicinal plant,Pharmacology,Persian Medicine,Ophthalmology,Ruta graveolens L.},
volume = {6},
Number = {1}, 
pages = {64-53}, 
publisher = {},

doi = {10.61186/pbp.6.1.64},
url = {http://pbp.medilam.ac.ir/article-1-208-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-208-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {SalavatyZadeh, Mohammad and KumarMandal, Sudip},  
title = {Herbal Remedies for Pediatric Earache in Traditional Iranian Medicine}, 
abstract ={Objective: Ear pain (earache) in children and infants often occurs when the ear canal becomes blocked, preventing fluid from draining. This blockage can lead to ear infections, causing pressure on the eardrum and resulting in pain. Other factors contributing to ear pain include infections, inflammation, fluid buildup, injury, and various health conditions. Ear pain is a particularly distressing condition. In Iranian traditional medicine, medicinal plants have long been used to alleviate ear pain in children. The aim of this study is to identify the medicinal plants effective in treating ear pain in children within the context of Iranian traditional medicine. Methods: A comprehensive search was conducted using keywords such as "medicinal plants," "traditional medicine," and "migraine" across reputable scientific databases including Web of Science, PubMed, Scopus, and Google Scholar. In the next phase, the extracted articles were carefully evaluated, and those not directly related to the research topic were excluded. Ultimately, only traditional sources that specifically examined the impact of medicinal plants on treating ear pain in children were selected for further review and analysis. Results:  In Iranian traditional medicine, a variety of medicinal plants are used to treat ear pain in children. These include cinnamon, clove, lavender, olive, garlic, licorice, eucalyptus, mint, onion, apple, ginger, radish, basil, echinacea, purslane, and chamomile. Conclusion:  Medicinal plants in Iranian traditional medicine are popular and trusted options for treating ear pain in children due to their natural properties and minimal side effects. These plants, with their anti-inflammatory, antiseptic, and soothing compounds, can help reduce pain and inflammation in children's ears. Utilizing medicinal plants is not only a natural and cost-effective treatment method but also culturally and historically significant, contributing to the preservation and promotion of Iranian traditional medicine. However, given the sensitivity of treating children, these remedies should be used under the supervision of a physician or a traditional medicine specialist to ensure the safety and effectiveness of the treatment.},  
Keywords = {Children, Ear Diseases, Earache, Traditional Medicine, Medicinal Plants},
volume = {6},
Number = {1}, 
pages = {65-68}, 
publisher = {},

doi = {10.61186/pbp.6.1.65},
url = {http://pbp.medilam.ac.ir/article-1-238-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-238-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {KakuyiNezhad, Melika and Ghaznavi, Ais},  
title = {A Review of the Most Important Medicinal Plants for Reducing Dental Plaque in Traditional Iranian Medicine}, 
abstract ={Objective: Dental plaque, a flexible white or yellow-gray substance, significantly contributes to periodontal diseases. This study aims to present medicinal plants used in traditional Iranian medicine for controlling and treating dental plaque. Methods: In this review study, keywords such as medicinal plant, traditional medicine, and dental plaque were utilized to search SID, Google Scholar, Megaran, PubMed, and Scopus databases. The article abstracts were reviewed, irrelevant studies excluded, and relevant ones selected for analysis. Results:  The findings revealed that medicinal plants like coconut, aloe vera, clove, orange, rosemary, black tea, mango, chebulic myrobalan, miswak, turmeric, barberry, licorice, pomegranate, and black mulberry are essential in traditional Iranian medicine for managing dental plaque. Conclusion:  The medicinal plants identified in this study have been suggested that by antioxidant, antimicrobial, and anti-inflammatory activities effectively combat dental plaques.},  
Keywords = {Keywords: Tooth, Dental plaque, Traditional medicine, Medicinal plants, Iran},
volume = {6},
Number = {1}, 
pages = {69-75}, 
publisher = {},

doi = {10.61186/pbp.6.1.69},
url = {http://pbp.medilam.ac.ir/article-1-224-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-224-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Akram, Muhammad and Zainab, Rida and Daniyal, Muhammad and Rasul, Shafqat and Munir, Navee},  
title = {Phytochemistry and Pharmacology of Artemisia absinthium Linn: A Multipurpose Medicinal Plant}, 
abstract ={Plants are nature's gift to humanity to acquire a healthy and prosperous life and used not only to treat several diseases but also as nutraceuticals to improve or modulate biological activities. About 500 species of Artemisia have been found in nature. Among them, Artemisia absinthium (A. absinthium) or wormwood is the most popular herb in the temperate zone of Northern Africa, Eurasia. It is widely distributed in the Northern United States and Canada and descriptions are found in almost all medicinal books of the Western World. It is grown as a decorative plant and is used in various alcoholic beverages as well as an ingredient in the spirit absinthe. The information regardingA. absinthiumethno pharmacological activities, phytochemistry, and its various medicinal uses wereexplored using different search engines in PubMed, Google Scholar, Research gate and Web of science. Different terms included "worm wood", "Artemisia absinthium", "and pharmacological", "therapeutic/medicinal uses" were used to find the scientific literatures. Studies have shown that A. absinthium possesses anti-bacterial, anti-depressant, anthelmintic, anti-malarial, antioxidant, antiprotozoal, antipyretic, anti-tumor, anti-ulcer, hepatoprotective and neuroprotective activities. These activities are attributed to various active metabolites present in A. absinthium, whereas for further research, these results are useful and valuable. Adverse properties of A. absinthium required severe efforts to identify, isolates, and validates the chemical constituents for their therapeutic potentials, which gives direction to develop a novel medicine for various diseases.          },  
Keywords = {Artemisia absinthium, nutraceuticals, medicinal uses, chemical constituents, pharmacological activity},
volume = {6},
Number = {1}, 
pages = {76-87}, 
publisher = {},

doi = {10.61186/pbp.6.1.76},
url = {http://pbp.medilam.ac.ir/article-1-172-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-172-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Ranjbari, Ali and Nazer, MohamadRez},  
title = {A Review of Medicinal Plants Effective on Wound Healing in the Western Part of Iran Based on Ethnobotanical Documents}, 
abstract ={Objective: The skin is a barrier between the human body and the external environment and protects the body against external chemical and physical factors. Despite major advances in wound treatment, wound healing remains one of the most important challenges ahead. Some medicinal plants with anti-inflammatory, antimicrobial and antioxidant properties are effective in healing and repairing wounds. The present study is a review of medicinal plants that are used in the ethnobotanical knowledge of western Iran for wound healing in skin wounds. Methodology: In this study, the keywords of medicinal plants, wound healing, skin wound, West Azerbaijan, East Azerbaijan, Kurdistan, Kermanshah, Ilam, Khuzestan and ethnobotany were used to search for articles. The investigated databases were Google Scholar, SID, Megaran, PubMed, Scopus. Related ethnobotanical articles were used to review the texts. Results: Based on the obtained results, it was determined that medicinal plants such as Sisymbrium sophia L, Fumaria officinalis L., Plantago major L., Alcea spp., Urtica spp., Astragalus gossypinus Fischer., Fumaria officinalis, Iperata cylindrica (L.), Polygonum aviculare L., Sanguisorba minor Scop., Alcea angulata, Aristolochia olivieri, Calendula persica, Citrullus colocynthis, Fumaria parviflora, Nerium oleander, Scrophularia striata, Allium schoenoprasum, Ixiolirion tataricum, Thymus Kotchyanous, Adonis aestivalis, Cardaria draba, Althaea officinalis, Beta vulgaris , Carthamus tinetorius L., Chrysanthemum coronarium, Helianthus annus L., Matricaria recutita L. and Vicia sativa are medicinal plants that heal wounds in these areas. Conclusion: Medicinal plants and plant derivatives due to the presence of antioxidant compounds and secondary medicinal compounds such as tannins, anthocyanins, flavon, flavonoids, phenols and also less side effects than chemical drugs and species diversity in the treatment of skin wounds and Reports of their traditional effects in the treatment of wounds present them as an inexpensive and effective choice for wound healing. The need for more pharmacological and clinical studies to produce wound healing drugs seems necessary and necessary.},  
Keywords = {Skin, Wound healing, Medicinal plants, Treatment, Iran},
volume = {6},
Number = {1}, 
pages = {88-92}, 
publisher = {},

doi = {10.61186/pbp.6.1.88},
url = {http://pbp.medilam.ac.ir/article-1-225-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-225-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Saadat, Fatemeh and FathiAzarbayjani, Anahit},  
title = {Albumin-Loaded Nanofiber for Topical Wound Healing}, 
abstract ={Objective: Intravenous albumin administration is known to improve blood circulation and promote wound healing, while topical albumin can inhibit bacterial growth on wounds. Additionally, topical caffeine has been reported to stimulate vascularization and enhance blood vessel formation in the skin. This study aimed to investigate, for the first time, the effect of topical albumin and caffeine individually and in combination—on wound healing rate in rat models. Methods: Albumin- and caffeine-loaded nanofibers were fabricated using the electrospinning technique. Nanofiber morphology was characterized using scanning electron microscopy (SEM) and their chemical composition was confirmed by Fourier-transform infrared spectroscopy (FT-IR). The therapeutic effects of the prepared nanofibers were evaluated in a full-thickness excision wound model in rats. Results: Both albumin alone and the albumin–caffeine combination significantly accelerated wound healing, with a marked reduction in the wound area compared to controls. By the end of week 2, wound contraction reached 96% in the albumin–caffeine nanofiber group, compared with 79% in the untreated control group. Conclusion: Topical application of albumin-loaded nanofiber dressings demonstrated potent wound-healing properties, further enhanced by the addition of caffeine. These findings suggest that albumin–caffeine nanofiber dressings could represent a promising and innovative approach for accelerating wound repair.},  
Keywords = {,Albumin,caffeine,nanofiber,wound healing},
volume = {6},
Number = {2}, 
pages = {1-7}, 
publisher = {},
url = {http://pbp.medilam.ac.ir/article-1-221-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-221-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Nazarbaghi, Surena and Eftekhari, Zohre},  
title = {Exploring Herbal Remedies for Migraine: Insights from the Medicinal Plants of Northern Iran}, 
abstract ={Objective: Migraine is a prevalent neurological disorder characterized by intense, unilateral headaches often accompanied by nausea, vomiting, and dizziness. This ethnobotanical review aims to identify medicinal plants traditionally used by the inhabitants of northern Iran for the management and relief of migraine symptoms. Methodology: A comprehensive literature review was performed using the keywords medicinal plants, traditional medicine, and migraine across major databases including Web of Science, PubMed, Scopus, and Google Scholar. Irrelevant studies were excluded, and the remaining articles were systematically reviewed to extract relevant ethnobotanical data. Results: Ethnobotanical data from the northern provinces of Iran (West Azarbaijan, East Azarbaijan, Ardabil, Gilan, Mazandaran, Golestan, and Khorasan) revealed the use of several medicinal plants in migraine management. These include Origanum vulgare, Rosa canina, Asperula odorata L., Zingiber officinale, Valeriana officinalis, Echium amoenum, Ocimum basilicum, Melissa officinalis, Tragopogon pratensis, Salvia officinalis, Rheum ribes, Viola suavis, Ferulago angulate, and Juniperus polycarpos. These plants are traditionally administered in various forms, such as decoctions, infusions, and extracts. Conclusion: Medicinal plants rich in analgesic, antispasmodic, and sedative compounds appear to offer therapeutic benefits in migraine management by reducing pain severity and promoting relaxation. While traditional knowledge supports their use, further pharmacological and clinical studies are warranted to confirm their efficacy and safety in evidence-based migraine therapy.},  
Keywords = {Brain, Pain, Migraine, Medicinal plants, Treatment, Iran},
volume = {6},
Number = {2}, 
pages = {8-14}, 
publisher = {},
url = {http://pbp.medilam.ac.ir/article-1-237-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-237-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {BaharvandAhmadi, Babak and Nafari, Amirhossein and Ahmadi, Kolsoum and HeydariNazarabad, Vahide and Mohammadi, Rasool and Almasian, Mohammad and Kiani, Ali Asghar},  
title = {Investigation of the Effects of Genetic Variations in CYP2C9 and VKORC1 on Warfarin Dose Requirements Among Iranian Patients from Khorramabad, Lorestan Province, West of Iran}, 
abstract ={Background: Warfarin, a commonly prescribed anticoagulant with a narrow therapeutic index, poses challenges in determining the appropriate dosage due to genetic variations among individuals. Incorrect dosing of warfarin can lead to catastrophic adverse events. Observational studies have shown that single nucleotide polymorphisms (SNPs) in the CYP2C9 and VKORC1 genes significantly influence warfarin dose requirements. This study aimed to examine the impact of various genotypes on warfarin dose requirements among Iranian patients. Methods: Blood samples were collected from 117 patients and stored in tubes containing EDTA. DNA was extracted, and the different alleles and genotypes of the studied SNPs were identified using the PCR-RFLP technique. Results: Among the 117 patients, no significant differences were observed in the mean daily warfarin dose requirement among the genotypes of the CYP2C93 (1075A>C) polymorphism. However, significant differences were found among the genotypes of CYP2C92 (430C>T). Furthermore, the mean daily warfarin dose requirements varied significantly among the wild-type, heterozygous, and mutant genotypes for two VKORC1 polymorphisms: VKORC1 (1173C>T) and VKORC1 (1639G>A). Conclusion: Our findings demonstrate that CYP2C9 and VKORC1 polymorphisms significantly affect warfarin maintenance dose requirements in Iranian patients. This information can improve the prediction of appropriate warfarin dosages and reduce the risk of over-anticoagulation or under-anticoagulation.},  
Keywords = {CYP2C9, genetic variations, VKORC1, warfarin},
volume = {6},
Number = {2}, 
pages = {15-24}, 
publisher = {},
url = {http://pbp.medilam.ac.ir/article-1-248-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-248-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Mivefroshan, Azam and Pirhadi, Mohadeseh},  
title = {Ethnobotanical Insights into Medicinal Plants and Their Mechanisms for Blood Pressure Control}, 
abstract ={Objective: Hypertension, characterized by elevated arterial blood pressure, constitutes a significant risk factor for a range of severe health complications, including cardiovascular disease, renal impairment, atherosclerosis, ocular damage, and stroke. This study aims to identify medicinal plants traditionally employed in the western region of Iran for the management of hypertension. Method: A comprehensive literature search was conducted to identify ethnobotanical knowledge pertaining to the use of medicinal plants for hypertension management in western Iran. The search encompassed the following databases: Google Scholar, SID, Magiran, PubMed, and Scopus. Relevant articles were retrieved using the keywords "medicinal plants," "Iran," "blood pressure," "Urmia," "Tabriz," "Kurdistan," "Kermanshah," "Ilam," "Khuzestan," and "ethnobotany." Results: Medicinal plants including Foeniculum vulgare Mill., Achillea millefolium L., Fumaria officinalis L., Apium graveolens, Urtica dioica L., Crataegus pontica C. Koch., Rheum ribes L., Allium schoenoprasum, Achillea biebersteinii, Achillea millefolium, Prunus cerasifera, Gentian olivieri, Olea europaea L., Rumex pulcher L. and Crataegus monogyna L. are antihypertensive medicinal plants in western Iran. Conclusion: Emerging evidence suggests that certain medicinal herbs and spices possess antihypertensive properties, demonstrating their potential as adjunctive or alternative therapeutic agents for blood pressure management.},  
Keywords = {Disease, Blood pressure, Medicinal plants, Remedy, Iran},
volume = {6},
Number = {2}, 
pages = {25-30}, 
publisher = {},
url = {http://pbp.medilam.ac.ir/article-1-226-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-226-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {ZarifFakoor, Elahe and Rezvanimanesh, Samad and Ahmadishoar, Shiva and Mehboodi, Mahtab and Mardani, Hamid Reza and Rastmanesh, Samad and Niknejad, Mohammad Amin and YousefianMobarekeh, Rosita and Eskandari, Shiva and Shirazi, Maede and Poureslamfar, Behnam},  
title = {A Review of the Antimicrobial Effects of Medicinal Plants on Staphylococcus aureus}, 
abstract ={This review meticulously examines the antimicrobial effects of medicinal plants on Staphylococcus aureus and underscores their potential in overcoming the challenge of drug resistance. With a plethora of plant species known for their antimicrobial properties, exploring alternative solutions to combat bacterial infections is imperative. The review emphasizes the importance of investigating plant-derived compounds that can effectively inhibit bacterial growth through unique mechanisms and discusses the synergistic effects of combining multiple compounds from plant extracts. Researchers are actively working on isolating novel bioactive chemicals from plants to serve as effective alternatives to traditional antibiotics. The study highlights the critical role of herbal medicines in addressing resistant strains of Staphylococcus aureus and stresses the necessity for further research to develop innovative treatment approaches.  },  
Keywords = {Medicinal plants, Staphylococcus aureus, antimicrobial effects, drug resistance, bioactive compounds, alternative treatments, multi-resistant strains},
volume = {6},
Number = {2}, 
pages = {31-45}, 
publisher = {},
url = {http://pbp.medilam.ac.ir/article-1-244-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-244-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {EishiOskuie, Ali and Abdi, Fatemeh},  
title = {Medicinal Plants Effective Against Anemia in Northwest Iran: A Review of Hematopoietic Medicinal Plants}, 
abstract ={Objective: Anemia, characterized by an insufficient number of healthy red blood cells, can be caused by blood loss, hemolysis, or impaired erythropoiesis. Types of anemia include iron-deficiency anemia and vitamin-deficiency anemia. Given their high iron and nutrient content, certain medicinal plants offer potential therapeutic benefits for anemia. This review aims to identify medicinal plants from Northwest Iran traditionally used for treating this condition. Methodology: To identify relevant literature, a comprehensive database search was conducted using keywords such as 'medicinal plants,' 'Iran,' 'anemia,' 'hematopoietic,' 'Urmia,' 'Tabriz,' 'Ardabil,' 'West Azerbaijan,' 'East Azerbaijan,' and 'ethnobotany. Databases such as Google Scholar, SID, Magiran, PubMed, and Scopus were used to search for relevant articles, particularly ethnobotanical studies related to the subject. Results: The review identified that medicinal plants such as Nasturtium sp., Salvia officinalis, Centaurea depressa, Centaurea virgate, Achillea biebersteinii, Cichorium intybus, Urtica dioica, Prunus cerasifera, Cichorium intybus, Saponaria officinalis, Foeniculum vulgare, Achillea millefolium, Berberis vulgaris, Capsella bursa-pastoris, Crataegus aronia, Adiantum capillus-Veneris, Anthemis cotula, Gandelia tourenfortii, Rheus ribes, Lactuca virosa, Hyssopus officinale, and Salix alba are used in traditional and ethnobotanical practices to treat anemia. Conclusion: Further research is recommended to conduct phytochemical analysis of these medicinal plants, identifying the active compounds that influence anemia and hematopoiesis. Additionally, clinical trials involving animal and human models could explore the potential of these plants as a basis for developing effective and affordable herbal combination drugs for the treatment of anemia.},  
Keywords = {Blood, Anemia, Hematopoietic, Medicinal plants, Treatment},
volume = {6},
Number = {2}, 
pages = {46-50}, 
publisher = {},
url = {http://pbp.medilam.ac.ir/article-1-231-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-231-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Patel, Akanksh and Purohit, Manmath},  
title = {Therapeutic Potentials of Ocimum sanctum Linn. (Tulsi): A Comprehensive Review of Its Pharmacological Activities}, 
abstract ={This review summarizes the diverse medicinal properties of Ocimum sanctum Linn. (Tulsi), a revered herb in Indian medicine. Traditionally praised for its pungency, warmth, and diverse medicinal uses, Tulsi's roots, leaves, and seeds each offer unique benefits. Ayurvedic texts categorize Tulsi as a stimulant, aromatic, and antipyretic, capable of balancing certain bodily energies while potentially aggravating others. Its primary benefits include relieving coughs, promoting sweating, and easing indigestion and appetite loss. More importantly, Tulsi demonstrates a remarkable range of biological activities. It exhibits antibacterial, antiviral, antifungal, and antiparasitic properties, making it effective against various pathogens and even malaria. Additionally, its analgesic, antipyretic, antiinflammatory, and anti-allergic properties offer relief from pain, fever, inflammation, and allergies. Tulsi also offers cardiovascular benefits, lowers blood pressure, and protects the heart. Beyond the physical, it shows promise in improving memory, regulating cholesterol, protecting the liver, and controlling diabetes and asthma. Notably, it exhibits antioxidant and anticancer properties, suggesting potential cancer prevention and radioprotection. Furthermore, Tulsi boasts immunomodulatory, antifertility, anti-ulcer, and anti-arthritic activities, highlighting its versatility. Its adaptogenic/antistress capabilities and potential to prevent cataracts and even skin conditions like leucoderma further showcase its therapeutic breadth. Given its vast and seemingly valuable medicinal properties, this review aims to equip researchers and clinicians with the knowledge necessary to properly utilize Tulsi in their endeavors.},  
Keywords = {,Medicinal properties,Ocimum sanctum (OS,Tulsi),Pharmacological activities},
volume = {6},
Number = {2}, 
pages = {51-67}, 
publisher = {},
url = {http://pbp.medilam.ac.ir/article-1-219-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-219-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Karimi, Kimiya and ZarifFakoor, Elahe and Ziaee, Toktam and Mehboodi, Mahtab and KhodaeiAtaloo, Pouria and Sanati, Masoud and Mohammadi, Zeynab and Dorzadeh, Mohammadreza and Rouzbeh, Kimia and Heshmati, Reyhaneh},  
title = {Antimicrobial Effects of Medicinal Plants on Streptococcus pyogenes: A Review}, 
abstract ={Streptococcus pyogenes is a pathogen of significant public health concern. It is the most common cause of bacterial pharyngitis and is responsible for serious conditions such as streptococcal toxic shock syndrome, necrotizing fasciitis, impetigo, and scarlet fever. Additionally, S. pyogenes is involved in post-streptococcal sequelae, including acute glomerulonephritis, acute rheumatic fever, rheumatic heart disease, and reactive arthritis. The increasing antibiotic resistance of S. pyogenes has led to a growing interest in exploring alternative treatments, such as medicinal plants, which may provide effective and safer options for preventing and treating diseases caused by this bacterium. Today, there is an increasing interest in medicinal plants due to less side effects, ease of use, availability, and usually affordability.  In conclusion, given the growing antibiotic resistance of Streptococcus pyogenes, this study investigates the inhibitory effects of medicinal plants against this pathogen. The aim is to assess the potential of these plants in preventing and treating diseases caused by S. pyogenes, as well as to elucidate their mechanisms of action on this bacterium.  },  
Keywords = {Streptococcus pyogenes, Antimicrobial effects, Medicinal plants, Drug resistance},
volume = {6},
Number = {2}, 
pages = {68-79}, 
publisher = {},
url = {http://pbp.medilam.ac.ir/article-1-243-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-243-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {BaharvandAhmadi, Babak and NarenjkarEsfahani, Reyhaneh},  
title = {Serum Levels of Glutathione and Malondialdehyde in Patients with Type 2 Diabetes with Coronary Heart Disease at Khorramabad Heart Hospital, Western Iran: A Cross-Sectional Study}, 
abstract ={Objective: Type 2 diabetes is linked to a heightened risk of coronary heart disease (CHD) due to metabolic and oxidative disturbances. Glutathione, a vital antioxidant, and malondialdehyde (MDA), a marker of oxidative stress, are critical in assessing oxidative damage and cellular stress. This study aims to examine the serum levels of these markers in patients with type 2 diabetes and CHD to gain insight into the relationship between oxidative stress and cardiovascular disease in this population. Methods: This cross-sectional study was conducted at Khorramabad Heart Hospital in Western Iran, involving 100 patients with type 2 diabetes with CHD (T2DM-CHD) over a two-month period. Blood samples were also collected from fasting volunteers in a control group for comparative purposes. After centrifugation and serum separation, biochemical assays were performed to measure serum levels of MDA and glutathione. Results: The serum level of MDA in the T2DM-CHD group was 19.3 ± 16.8 µmol/mg protein, significantly higher than the control group’s level of 6.9 ± 3.3 µmol/mg protein. Conversely, serum glutathione levels in the diabetic group were 15.3 ± 6.5 µmol/mg protein, markedly lower compared to the control group’s 34.8 ± 10 µmol/mg protein. Conclusion: The findings suggest that patients with T2DM-CHD exhibit elevated levels of MDA and reduced levels of glutathione, indicating significant oxidative stress. This imbalance may contribute to the progression of diabetes-related complications and cardiovascular diseases. Therefore, incorporating antioxidants as medications or supplements may be an effective strategy to mitigate oxidative stress and enhance clinical outcomes in these patients. Further research is required to identify the optimal types and dosages of antioxidants.},  
Keywords = {Cardiovascular disease, Type 2 diabetes, Coronary artery disease, Diabetes, Iran},
volume = {6},
Number = {2}, 
pages = {80-83}, 
publisher = {},
url = {http://pbp.medilam.ac.ir/article-1-247-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-247-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {JafariHeydarlou, Mohammad and JAlkhatib, Ahe},  
title = {Herbal Whitening Agents: Traditional Remedies for Reducing Tooth Discoloration}, 
abstract ={Objective: Although professional dental whitening techniques such as composite bonding, veneers, and bleaching are widely practiced, traditional and herbal remedies offer effective, accessible, and potentially safer alternatives. These natural methods may contribute to the reduction of yellow and brown stains while minimizing adverse effects often associated with chemical procedures. Methods: This review was conducted through systematic keyword searches including “medicinal plants,” “traditional medicine,” “tooth discoloration,” and “tooth whitening” in databases such as Web of Science, Medline, PubMed, Scopus, and Google Scholar. Relevant studies and ethnobotanical sources were reviewed to compile and synthesize the available evidence. Results: Traditional Iranian medicine documents a variety of herbal remedies with tooth-whitening properties. These include lemon juice, turmeric, coconut oil, strawberries, orange peel, apple cider vinegar, banana peel, Persian pomegranate, licorice root, mint, wild thyme, and myrtle. Conclusion: The tooth-whitening effects of these natural agents are attributed to multiple mechanisms, including mild abrasiveness, pigment degradation, antibacterial and anti-inflammatory actions, and direct bleaching effects. When applied consistently and appropriately, these remedies may contribute not only to the maintenance of dental aesthetics but also to improved oral health. Further clinical investigations are warranted to validate their efficacy and optimize safe usage protocols.},  
Keywords = {Tooth, Tooth yellowness, Whitening, Beauty, Traditional medicine},
volume = {6},
Number = {2}, 
pages = {84-88}, 
publisher = {},
url = {http://pbp.medilam.ac.ir/article-1-235-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-235-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Zolfigol, Ali and Pirhadi, Mohadeseh},  
title = {Exploring Herbal Remedies for Infant Colic: Traditional Plants with Therapeutic Potential}, 
abstract ={Objective: Neonatal colic is among the most common gastrointestinal disorders in newborns, often causing persistent crying, restlessness, and significant distress for both infants and parents. This condition typically occurs between 1 and 4 months of age and may be managed through home remedies, medical interventions, maternal dietary modifications, or pharmacological treatments. In Iranian traditional medicine, medicinal plants play a key role in alleviating colic. This study aims to identify and report the main medicinal plants used for the treatment of colic in infants. Methodology: This review was conducted through a comprehensive search using keywords including “colic,” “children,” “traditional medicine,” “medicinal plants,” and “treatment” in databases such as Google Scholar, SID, Magiran, and Scopus. Irrelevant studies were excluded, and eligible articles were systematically reviewed and analyzed. Results: Findings revealed that medicinal plants such as Anethum graveolens, Acorus calamus, Foeniculum vulgare, Pimpinella anisum, Matricaria chamomilla, Mentha spicata, Zingiber officinale, and Carum carvi are among the most frequently recommended and practically applied herbal remedies for infantile colic in traditional medicine sources. Conclusion: Anti-colic medicinal plants appear to alleviate symptoms of infantile colic through analgesic, antispasmodic, and sedative mechanisms. These findings highlight the therapeutic potential of medicinal plants as a complementary approach for colic management. However, clinical validation and careful monitoring by healthcare professionals are necessary to ensure efficacy and safety in infants.},  
Keywords = {Digestive system, Children, Colic, Pain, Medicinal plants, Traditional medicine},
volume = {6},
Number = {2}, 
pages = {89-94}, 
publisher = {},
url = {http://pbp.medilam.ac.ir/article-1-228-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-228-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Mami, Sajad and Veisi, Kosar and Azizian, Hajar and Mami, Sanaz and Noorikia, Parisa and Mohamadi, Ghazal and Rahmani, Zohreh},  
title = {Investigating the Impact of a polyherbal Syrup Containing Licorice, Peppermint, and Chamomile Extracts on Inflammation and Peptic Ulcers in Male Rats}, 
abstract ={Objective: Peptic ulcers are caused by erosion of the gastric mucosa, often triggered by excessive gastric acid secretion, aspirin use, or Helicobacter pylori infection. These ulcers can lead to pain, inflammation, and bleeding. Although conventional therapies, including antibiotics and surgery, are effective, they are frequently associated with side effects and significant economic burden. Medicinal plants, valued for their anti-inflammatory and gastroprotective properties, are widely used in traditional medicine. This study aimed to evaluate the combined effect of hydroalcoholic extracts of licorice (Glycyrrhiza glabra), peppermint (Mentha piperita), and chamomile (Matricaria chamomilla) on peptic ulcer healing, compared with the effects of individual extracts. Method: Licorice, peppermint, and chamomile plants were collected from the Zagros Mountains (Ilam Province, Iran), authenticated, and extracted using the Soxhlet method. Forty-nine male rats were divided into seven groups, with gastric ulcers induced by aspirin administration and Helicobacter exposure. Animals were anesthetized with ketamine and xylazine and euthanized according to ethical guidelines. Stomachs were excised for macroscopic and histopathological analysis of ulcer healing, inflammation, and epithelial regeneration. Results: Chamomile and peppermint-treated groups showed slow and incomplete ulcer healing after 21 days, with persistent inflammation and bleeding in deeper tissues. Licorice-treated rats exhibited more pronounced recovery, with significant epithelial regeneration, although some ulcer depth remained unhealed. The polyherbal-treated group demonstrated marked improvement of gastric wall tissue, with advanced epitheliogenesis and near-complete healing comparable to the standard Recolic-treated group. Minimal inflammatory cells and vascular congestion persisted in some areas. Conclusion: The combination of licorice, peppermint, and chamomile extracts promoted superior gastric ulcer healing compared to individual plant treatments, supporting the therapeutic potential of polyherbal formulations. Further experimental and clinical studies are warranted to optimize dosage, validate efficacy, and explore their potential integration into peptic ulcer management strategies.},  
Keywords = {Digestive system, Stomach, Gastric ulcer, Medicinal plants, Treatment},
volume = {6},
Number = {2}, 
pages = {95-102}, 
publisher = {},
url = {http://pbp.medilam.ac.ir/article-1-255-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-255-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}

@article{ 
author = {Ghaznavi, Aisan and Lysiuk, Rom},  
title = {Anti-Toothache Medicinal Plants Used in Ethnobotanical Knowledge}, 
abstract ={Objective: Toothache, commonly resulting from dental caries, fractures, or thermal sensitivity, is among the most distressing forms of pain. Traditional medicine and ethnobotanical knowledge have long utilized medicinal plants for toothache relief. This study aims to identify and document the medicinal plants traditionally used across Iran to alleviate toothache. Methodology: A comprehensive literature review was conducted using keywords including medicinal plants, Iran, tooth, toothache, and ethnobotany. Databases such as Google Scholar, SID, Magiran, PubMed, and Scopus were systematically searched. Relevant ethnobotanical studies were screened and analyzed to compile a list of plants traditionally employed for toothache management. Results: Several medicinal plants were identified as prominent remedies for toothache in Iranian ethnobotany, including Origanum vulgare, Papaver somniferum, Mentha aquatica L., Mentha spicata L., Ferula persica Willd., Glycyrrhiza glabra L., Perovskia abrotanoides Kar., Dianthus caryophyllus, Viola odorata, Astragalus verus, Zingiber officinale, Allium sativum, and Thymus danensis. These plants are traditionally administered in various forms such as decoctions, powders, and topical applications to relieve pain and inflammation. Conclusion: Iran’s rich botanical diversity and extensive ethnomedicinal heritage provide valuable resources for the treatment of toothache. The findings underscore the potential of these plants as sources for developing novel analgesic and anti-inflammatory agents. Further pharmacological and clinical studies are recommended to validate their efficacy and safety for modern dental applications.},  
Keywords = {Tooth, Toothache, Traditional medicine, Ethnobotany, Medicinal plants, Treatment, Iran},
volume = {6},
Number = {2}, 
pages = {103-107}, 
publisher = {},
url = {http://pbp.medilam.ac.ir/article-1-234-en.html},  
eprint = {http://pbp.medilam.ac.ir/article-1-234-en.pdf},  
journal = {Plant Biotechnology Persa},  
issn = {2676-7414}, 
eissn = {2676-7414}, 
year = {2024}  
}