Volume 5, Issue 1 (6-2023)
pbp 2023, 5(1): 1-7 |
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Zangeneh M M, Zangeneh A, Etemadi N, Tabatabaei Aghda S J, Pourkamalzadeh M, Zand S, et al . The Effect of Nano Silver Particles of the Aqueous Extract of Artemisia aucheri on the Healing Process of Skin Wounds in Rats. pbp 2023; 5 (1) :1-7
URL: http://pbp.medilam.ac.ir/article-1-331-en.html
URL: http://pbp.medilam.ac.ir/article-1-331-en.html
Mohammad Mehdi Zangeneh1 
, Akram Zangeneh1 , Navid Etemadi *2 , Seyyed Jamaleddin Tabatabaei Aghda3 , Mahtab Pourkamalzadeh3 , Samira Zand3 , Mohammad Abbaszadeh4 , Reza Asadzadeh5
, Akram Zangeneh1 , Navid Etemadi *2 , Seyyed Jamaleddin Tabatabaei Aghda3 , Mahtab Pourkamalzadeh3 , Samira Zand3 , Mohammad Abbaszadeh4 , Reza Asadzadeh5
1- Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran
2- DVM Graduate, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran ,navid@ymail.com
3- Department of Microbiology, Faculty of veterinary Medicine, Urmia University, Urmia, Iran
4- Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
5- Assistant Professor of Nephrology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran
2- DVM Graduate, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran ,
3- Department of Microbiology, Faculty of veterinary Medicine, Urmia University, Urmia, Iran
4- Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
5- Assistant Professor of Nephrology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran
Abstract: (1 Views)
Objectives: One of the application areas of nanobiotechnology is the use of silver nanoparticles (Nanosilver particles) for a new solution in medical treatments. In the present study, the researchers investigate the effect of nano silver particles of the aqueous extract of Artemisia aucheri on skin wound healing among male rats.
Material and Methods: After creating wounds in 48 rats, they were randomly divided into 6 groups. Treated with 0.2% AgNPs ointment, 0.2% AgSO4 ointment, 0.2% A. aucheri ointment, 3% tetracycline ointment, Eucerin basal ointment, and untreated control group. The tested groups were treated for ten days.
Results: Treatment with AgNPs ointment significantly increased the amount of vascular contraction, hexose amine and hydroxyproline, and fibrocyte and fibrocyte to fibroblast ratio. Also, in the mentioned group, the wound area and the total number of cells, neutrophils and lymphocytes decreased significantly compared to other groups.
Conclusion: The nano silver particles of the aqueous extract of A. aucheri accelerate the healing process of skin wounds and reduce the time required for complete wound healing.
Material and Methods: After creating wounds in 48 rats, they were randomly divided into 6 groups. Treated with 0.2% AgNPs ointment, 0.2% AgSO4 ointment, 0.2% A. aucheri ointment, 3% tetracycline ointment, Eucerin basal ointment, and untreated control group. The tested groups were treated for ten days.
Results: Treatment with AgNPs ointment significantly increased the amount of vascular contraction, hexose amine and hydroxyproline, and fibrocyte and fibrocyte to fibroblast ratio. Also, in the mentioned group, the wound area and the total number of cells, neutrophils and lymphocytes decreased significantly compared to other groups.
Conclusion: The nano silver particles of the aqueous extract of A. aucheri accelerate the healing process of skin wounds and reduce the time required for complete wound healing.
Received: 2025/08/17 | Accepted: 2023/06/22 | Published: 2023/06/22
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