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Germame Y, Atnafu H. Bioactive Compound Identification and Phytochemical Analysis of Mucuna pruriens Seed Extract. pbp 2026; 8 (In press)
URL: http://pbp.medilam.ac.ir/article-1-335-en.html
URL: http://pbp.medilam.ac.ir/article-1-335-en.html
1- Researcher at Ethiopian Biodiversity Institute , yordanosgermame@gmail.com
2- Researcher at Ethiopian Biodiversity Institute
2- Researcher at Ethiopian Biodiversity Institute
Abstract: (27 Views)
Objective: Mucuna pruriens, commonly known as velvet bean, is a climbing legume belonging to the family Fabaceae. The aim of the present study was to investigate qualitative and quantitative phytochemical analysis and to identify the bioactive compounds in the ethanolic extract of Mucuna pruriens seed using GC-MS technique.
Methods: Dried powder form of Mucuna pruriens was extracted with ethanol by using a 1:10 dilution, in cold maceration. The extract was evaporated into dryness using a hot water bath for 72 hrs. The GC-MS analysis of M. pruriens seed extract was performed using GC -MS equipment (Agilent Technologies) to identify the phytochemical constituents. While the compound mass spectra contained in the extract has been matched with the National Institute of Standards and Technology (NIST) library.
Result: The preliminary phytochemical screening revealed the presence of Alkaloids, flavonoids, phenol, saponin, steroids, tannin and terpenoids. The analysis by Gas chromatography-mass spectrometry results showed the presence of five major bioactive compounds.
Conclusion: Antioxidant, antifungal, antimicrobial, anti-inflammatory, anti-cancer, and anti-Parkinsonian properties have been reported to compounds which were found in present study.
Methods: Dried powder form of Mucuna pruriens was extracted with ethanol by using a 1:10 dilution, in cold maceration. The extract was evaporated into dryness using a hot water bath for 72 hrs. The GC-MS analysis of M. pruriens seed extract was performed using GC -MS equipment (Agilent Technologies) to identify the phytochemical constituents. While the compound mass spectra contained in the extract has been matched with the National Institute of Standards and Technology (NIST) library.
Result: The preliminary phytochemical screening revealed the presence of Alkaloids, flavonoids, phenol, saponin, steroids, tannin and terpenoids. The analysis by Gas chromatography-mass spectrometry results showed the presence of five major bioactive compounds.
Conclusion: Antioxidant, antifungal, antimicrobial, anti-inflammatory, anti-cancer, and anti-Parkinsonian properties have been reported to compounds which were found in present study.
Keywords: Mucuna pruriens, phytochemical analysis, GC-MS analysis, bioactive compounds, antioxidant activity
Type of Study: Research |
Subject:
Herbal Drugs
Received: 2025/08/21 | Accepted: 2025/09/25 | Published: 2026/01/20
Received: 2025/08/21 | Accepted: 2025/09/25 | Published: 2026/01/20
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