1- COMSATS University Islamabad, Pakistan
2- COMSATS University Islamabad, Pakistan , drnaseer@comsats.edu.pk
3- COMSATS University Islamabad Pakistan
Abstract: (47 Views)
Objective: Schistosomiasis affects more than 230 million people worldwide each year. Aquatic snails, which serve as the intermediate hosts, play a key role in transmitting the disease. The present systematic review compiles data on the molluscicidal activity of plants and their phytochemicals to help minimize the incidence of schistosomiasis.
Methodology: Online databases such as Google Scholar, PubMed, and ScienceDirect were searched for articles published between 2000 and 2022. In total, 290 articles were identified, of which 193 were included; studies involving snail species not associated with schistosomiasis were excluded. Data such as snail species, plant species and family name, plant parts used, assessment type, and phytoconstituents were analyzed.
Results: This review identified 279 plant species with molluscicidal activity, most belonging to the families Euphorbiaceae (9.31%), Solanaceae (7.16%), Asteraceae (6.09%), Leguminosae (5.73%), and Lamiaceae (4.3%). The most frequently used plant parts were leaves (48.74%), followed by seeds (12.9%), fruits (15.05%), roots (14.69%), stems (12.54%), and bark (10%).
Conclusion: Moreover, the review highlights the major plant phytochemicals and mechanisms of molluscicidal activity. Plants and their phytochemicals are promising resources for controlling snail species associated with schistosomiasis. Future studies should focus on identifying and isolating active phytochemicals and clarifying their mechanisms of molluscicidal action.
Type of Study:
Review/Systemtic review |
Subject:
Herbal Drugs Received: 2025/08/26 | Accepted: 2025/09/2 | Published: 2025/12/1