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Mivefroshan A. An Insight into the Most Important Medicinal Plants for Improving Metabolic Syndrome in Traditional Iranian Medicine. pbp 2025; 7 (In press)
URL: http://pbp.medilam.ac.ir/article-1-343-en.html
URL: http://pbp.medilam.ac.ir/article-1-343-en.html
Department of Internal Medicine, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran , dr.azam2011@gmail.com
Abstract: (40 Views)
Objective: Metabolic syndrome is a multifactorial disorder characterized by visceral obesity, hypertension, hypertriglyceridemia, low HDL-C levels, and insulin resistance, and it represents a major risk factor for type 2 diabetes and cardiovascular diseases. Alongside lifestyle modifications, medicinal plants have long been employed as complementary approaches for the prevention and management of this condition. Traditional Iranian medicine (TIM) has documented a wide variety of plants believed to influence the components of metabolic syndrome. The aim of this review was to identify the most important medicinal plants reported in TIM sources and to examine the available scientific evidence regarding their role in the prevention and treatment of metabolic syndrome.
Methodology: This review was conducted systematically. Relevant literature from authoritative TIM texts as well as international databases including PubMed, Scopus, Web of Science, and Google Scholar was thoroughly searched. Keywords related to metabolic syndrome and medicinal plants were used in both Persian and English. Inclusion criteria encompassed studies investigating the effects of medicinal plants on the prevention, management, or treatment of metabolic syndrome components.
Results: The review revealed that numerous plants, including Aloe vera, green tea, Citrullus colocynthis, chamomile, turmeric, ginger, barberry, milk thistle, nettle, chicory, bitter orange, savory, rosemary, pomegranate, garlic, dill, Tribulus terrestris, artichoke, lemon balm, Astragalus, oat, borage, flaxseed, black cumin, thyme, saffron, cinnamon, coriander, rhubarb, hemp, peppermint, passionflower, valerian, wild radish, Peganum harmala, and fennel, have been traditionally used in TIM for controlling or improving features of metabolic syndrome. Experimental and clinical evidence supports some of these plants in enhancing insulin sensitivity, lowering lipid levels, regulating blood pressure, and controlling body weight.
Conclusion: The findings suggest that medicinal plants documented in TIM may serve as complementary options in the management of metabolic syndrome. Despite encouraging preliminary evidence, much of the current data is derived from animal studies or traditional reports, highlighting the need for rigorously designed clinical trials to confirm their safety and efficacy. This review provides a foundation for future research and the development of evidence-based herbal interventions.
Methodology: This review was conducted systematically. Relevant literature from authoritative TIM texts as well as international databases including PubMed, Scopus, Web of Science, and Google Scholar was thoroughly searched. Keywords related to metabolic syndrome and medicinal plants were used in both Persian and English. Inclusion criteria encompassed studies investigating the effects of medicinal plants on the prevention, management, or treatment of metabolic syndrome components.
Results: The review revealed that numerous plants, including Aloe vera, green tea, Citrullus colocynthis, chamomile, turmeric, ginger, barberry, milk thistle, nettle, chicory, bitter orange, savory, rosemary, pomegranate, garlic, dill, Tribulus terrestris, artichoke, lemon balm, Astragalus, oat, borage, flaxseed, black cumin, thyme, saffron, cinnamon, coriander, rhubarb, hemp, peppermint, passionflower, valerian, wild radish, Peganum harmala, and fennel, have been traditionally used in TIM for controlling or improving features of metabolic syndrome. Experimental and clinical evidence supports some of these plants in enhancing insulin sensitivity, lowering lipid levels, regulating blood pressure, and controlling body weight.
Conclusion: The findings suggest that medicinal plants documented in TIM may serve as complementary options in the management of metabolic syndrome. Despite encouraging preliminary evidence, much of the current data is derived from animal studies or traditional reports, highlighting the need for rigorously designed clinical trials to confirm their safety and efficacy. This review provides a foundation for future research and the development of evidence-based herbal interventions.
Keywords: Metabolic syndrome, Medicinal plants, Phytotherapy, Traditional Iranian medicine, Herbal medicine, Cardiovascular diseases, Insulin resistance
Type of Study: Research |
Subject:
Phytomedicine
Received: 2024/12/12 | Accepted: 2025/08/23 | Published: 2025/12/1
Received: 2024/12/12 | Accepted: 2025/08/23 | Published: 2025/12/1
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