Volume 5, Issue 2 (12-2023)                   pbp 2023, 5(2): 131-136 | Back to browse issues page

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1- Medicine, Quran and Hadith Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
2- Department of Biology, Faculty of Science, Razi University, 67149-67346, Kermanshah, Iran , yousofnam@yahoo.com
Abstract:   (2082 Views)
Objectives: One of the application areas of nanobiotechnology is the use of silver nanoparticles (Nanosilver particles) for a new solution in medical treatments. In the present study, the researchers investigate the effect of nano silver particles of the aqueous extract of Artemisia aucheri on skin wound healing among male rats.
Material and Methods: After creating wounds in 48 rats, they were randomly divided into 6 groups. Treated with 0.2% AgNPs ointment, 0.2% AgSO4 ointment,   0.2% A. aucheri  ointment, 3% tetracycline ointment, Eucerin basal ointment, and untreated control group. The tested groups were treated for ten days.
Results: Treatment with AgNPs ointment significantly increased the amount of vascular contraction, hexose amine and hydroxyproline, and fibrocyte and fibrocyte to fibroblast ratio. Also, in the mentioned group, the wound area and the total number of cells, neutrophils and lymphocytes decreased significantly compared to other groups. 
Conclusion: The nano silver particles of the aqueous extract of A. aucheri accelerate the healing process of skin wounds and reduce the time required for complete wound healing.
Full-Text [PDF 641 kb]   (105 Downloads)    
Type of Study: Research | Subject: Herbal Drugs
Received: 2022/11/22 | Accepted: 2022/11/23 | Published: 2022/11/23

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