Volume 5, Issue 1 (3-2023)
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Hosseini S M, yousofvand N. Anti-anxiety and antioxidant properties of the zinc nanoparticles green-formulated by an ethnomedicinal plant in the in vivo condition. Journal title 2023; 5 (1)
URL: http://pbp.medilam.ac.ir/article-1-166-en.html
URL: http://pbp.medilam.ac.ir/article-1-166-en.html
Department of Biology, Faculty of Science, Razi University, 67149-67346, Kermanshah, Iran , yousofnam@yahoo.com
Abstract: (1160 Views)
Recently, the medicinal plants green-synthesized metallic nanoparticles have been used due to the therapeutic effects such as neuroprotective properties. In the recent study, the application of zinc nanoparticles containing Ocimum basilicum leaf aqueous extract on anxiety in male mice was investigated. The results of analyzing the absorption spectrum of zinc nanoparticles by FT-IR method showed that these nanoparticles show absorption peaks at wavelengths of 3448, 2955, 1624, 1040 and 539, that these peaks are related to O-H, C-H, C=O, C-O and Zn-O bonds in these nanoparticles, respectively. The results of examining the antioxidant properties of zinc nanoparticles in the DPPH free radical test revealed that the nanoparticles have excellent antioxidant effects against the DPPH free radical. ZnNPs green-synthesized by Ocimum basilicum could reduce the anxiety in male mice at the Light/dark transition test. After doing the clinical trial studies, the recent nanoparticles may be used as a neuroprotective supplement in humans.
Type of Study: Research |
Subject:
Herbal Drugs
Received: 2022/11/22 | Accepted: 2022/11/23 | Published: 2022/11/23
Received: 2022/11/22 | Accepted: 2022/11/23 | Published: 2022/11/23
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