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Dalili A, Roosta Y, Ranjbari A. Successfulness of Hair Follicular Transplantation for Melanocytes Activation in Vitiligo. pbp 2026; 8 (In press) :93-97
URL: http://pbp.medilam.ac.ir/article-1-211-en.html
1- Department of General Surgery, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
2- Department of Internal Medicine, Faculty of Medicine, University of Medical Sciences, Urmia, Iran
3- Department of General Surgery, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran , aliranjbari58@gmail.com
Abstract:   (2106 Views)
Objective: Vitiligo is a common skin disorder characterized by depigmented patches. Despite multiple treatment options, outcomes are often unsatisfactory, particularly in patients with stable vitiligo. This study aimed to evaluate the efficacy of healthy hair follicle transplantation (FUT) for treating segmental or stable vitiligo.
Methods: This prospective study included all eligible patients with stable vitiligo in nonglabrous regions who were referred to the dermatology department of Urmia Imam Khomeini Hospital from March 2021 to February 2022. Patients underwent comprehensive evaluation to document the number, size, location, and type of vitiligo lesions. Treatment outcomes were assessed by both subjective and objective measures, focusing on reduction in lesion size and improvements in associated leukotrichia.
Results: Among 57 patients, 20 (35%) were male and 37 (65%) female, with a mean age of 29.2 ± 4.4 years. Excellent repigmentation was observed in 31 patients (54.8%), good in 18 (32.2%), fair in 5 (8.2%), and poor in 3 (4.8%). Excellent color match was achieved in 54 patches (94.7%). Perifollicular repigmentation was <2 mm in 6 patients (10%), 2–4 mm in 33 patients (57.9%), and 5–10 mm in 18 patients (31.6%).
Conclusion: FUT is a safe and effective approach for localized and segmental vitiligo, particularly in hair-bearing areas. While labor-intensive, it promotes rapid recovery, minimal morbidity, and excellent color match, supporting its use as a reliable therapeutic option

 
     
Type of Study: Research | Subject: Phytomedicine
Received: 2024/02/3 | Accepted: 2024/02/5 | Published: 2024/02/6

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