Volume 4, Issue 1 (6-2022)                   2022, 4(1): 60-67 | Back to browse issues page

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Mahale B, Palwe S, Gajbhiye A, Bagul V, Kadam V. Phytochemical Investigations of Flower Drug from Plant Acmella Paniculata (Wall. Ex DC.) R. K. Jansen. Plant Biotechnology Persa 2022; 4 (1) :60-67
URL: http://pbp.medilam.ac.ir/article-1-114-en.html
MGV Arts Science and Commerce College Surgana Dist Nashik India , bhagwanmahale3@gmail.com
Abstract:   (877 Views)
Objective: Acmella paniculata (Wall. Ex DC.) R. K. Jansen, also known as Akkalkadha or toothache plant is an important medicinal herb of the Asteraceae family that grows in the tropics and subtropics of the world.
Material and Methods: The present phytochemical investigation aimed at evaluating the impact of different solvents on extraction yields, ash analysis, fluorescence analysis and phytochemical compounds from flower drug of A. paniculata plant. The results indicate that solvents have a significant impact in the yield of extraction.
Results: Resulting in the higher extraction yield in solvent distilled water and ethanol. Flavonoids, alkaloids, tannins, saponins, cardiac glycosides, and terpenoids are found in the crude flower drug of the plant.
Conclusion: The present study is useful in drug standardization, identifying the adulteration in the Ayurvedic medicines from this plant.
Full-Text [PDF 2401 kb]   (303 Downloads)    
Type of Study: Research | Subject: Bioactive Compounds
Received: 2022/04/22 | Accepted: 2022/05/7 | Published: 2022/05/7

1. Ballabh B and Chaurasia O P, Traditional medicinal plants of cold desert Ladakh used in treatment of cold, cough and fever. J Ethnopharmacol 2007, 112 (2): 341-345.
2. Pandey M M, Rastogi S, Rawat A K S, Indian traditional ayurvedic system of medicine and nutritional supplementation, Evidence Based Comp. and Alt. Med 2013, 2013, 1-12.
3. Essawi Tand Srour M, Screening of some Palestinian medicinal plants for antibacterial activity, J Ethnopharmacol 2000, 70, 343-349.
4. Sumathi P and Parvathi A, Antimicrobial activity of some traditional medicinal plants. J Med Plants Res 2010; 4 (4): 316-321.
5. Krishna M P, Varghese R, Mohan M and Mohamed Hatha A A, Antibacterial activity of Acmella paniculata extract on human pathogenic bacteria. Int JHerbal Med 2014; 2 (1): 132-134.
6. Sahaya S, Servin W and Devi B C, Antimicrobial activity of in vitro raised Acmella calva (DC.), Int J Pharm Pharm Sci 2012; 4:124-127.
7. Purushothaman Y, Gunaseelan S and Vijayakumar S D, Spilanthes acmella and its medicinal uses- a review, Asian J Pharm Clin Res 2018, 11 (6): 45-49.
8. Prachayasittikul S, Ruchirawat S and Prachayasittikul V, High therapeutic potential of Spilanthes acmella: A Review, Veda / EXCLI Journal, 2013,12, 291-312.
9. Pushpangadan P and Atal C K, Ethnomedical and ethnobotanical investigations among some scheduled caste communities of travancore, Kerala, India, Journal of Ethnopharmacology, 1986, 16(2)175-190.
10. Teklehaymanot T, Giday M, Medhin G and Mekonnen Y, Knowledge and use of medicinal plants by people around Debre Libanos monastery in Ethiopia, J Ethnopharmacol 2007; 111(2): 271-283.
11. Sabitha Rani A, Sana H, Sulakshana G, Puri E S and Keerti M, Spilanthes acmella- an important medicinal plant, Int J Minor Fruits Med Aromatic Plants 2019; 5 (2): 15- 26.
12. Jondiko I J O, A mosquito larvicide in Spilanthes mauritiana, Phytochem 1986; 25 (10): 2289–2290.
13. Kadir H A, Zakaria M B, Kechil A A, and Azirun M S, Toxicity and electrophysiological effects of Spilanthes acmella Murr. Pesticide Sci 1989; 25 (4): 329–335.
14. Mukharya D K and Ansari A H, Olean-12-en-3-O-betaD-galactopyranosyl (1-4)-O-alpha-L-rhamnopyranoside: a new triterpenoidal saponin from the roots of Spilanthes acmella (Murr.). Indian J Chem Biol 1987; 26–86.
15. Yasuda I, Takeya K, and Itokawa H, The geometric structure of spilanthol, Chemical & Pharmaceutical Bulletin. 1980; 28 (7): 2251–2253.
16. Dubey S, Maity S, Singh M, Saraf S A and Saha S, Phytochemistry, Pharmacology and Toxicology of Spilanthes acmella: A Review, Adv Pharmacol Sci 2013; 1-9.
17. Patel S, Gamit S, Qureshimatva U and Solanki H, Distribution Patterns of Acmella paniculata (Wall. Ex DC.) R. K. Jansen in Gujarat, India. Int JResearch Advent Technol 2019; 7 (5): 186-191.
18. Jansen R K, The systematics of Acmella (Asteraceae-Heliantheae), Systematic Botany Monographs 1985; 1-115.
19. El-Wahab A E A, Ghareeb D A, Sarhan E E, Rao T M, Rao B G and Rao Y V, Antioxidant activity of Spilanthes acmella extracts. Int J Phytopharm 2012; 3 (2): 216-220.
20. Kharshiing EV, Aqueous extracts of dried fruits of Zanthoxylum armatum DC., (Rutaceae) induce cellular and nuclear damage coupled with inhibition of mitoticactivity in-vivo. Am J Plant Sci 2012; 3 (11): 1646-1653.
21. Maimulyanti A and Prihadi A, Chemical composition of essential oil and hexane extract and antioxidant activity of various extracts of Acmella uliginosa (Sw.) Cass flowers from Indonesia. Agric Nat Resour 2016; 50 (4): 264-269.
22. Gairola K, Gururani S, Kumar R, Prakash O, Agarwal S and Dubey S, Phytochemical composition, antioxidant, and anti-inflammatory activities of essential oil of Acmella uliginosa (Sw.) Cass. grown in North India Terai region of Uttarakhand. Trends Phytochem Res 2021; 5 (1): 44-52.
23. Kumar KS and Ravindra N, Spilanthes acmella: Pharmacognostic and Phytochemical studies. J Pharm Adv Res 2018; 1(7): 329-334.
24. Hait M, Behera SK, Chaturwedi AK and Vaishnav MM, Exploration of phytochemical potential on flower of Butea monosperma. JPharmacognosy and Phytochem 2019; 8(3): 2083-2085.
25. Bagul VR, Mahale BN, Palwe SD, Gajbhiye AV and Kadam VV, In-Vitro Phytochemical Screening of the Flower Extracts of Butea monospema (Lam.) Taub. Int JCurrent Res 2021; 13 (3): 16645-16649.
26. Anbalagan S, Sankareswaran M, Moorthy M, Elakkia B, Fahamitha E, Phytochemical Analysis and Antifungal Activity of Vitex negundo Leaf Extracts Against Clinically Isolated Fungal Pathogens. Indian J Appl Microbiol 2017; 20(2): 119-125.
27. Harborne JB, Phytochemical Methods: A Guide to Modern Techniques of plant Analysis, London: Chapman and Hall Ltd., 1973; 49-279.
28. Kokate CK,1994, Practical pharmacognosy, Ed. 4, New Delhi: Vallabh Prakashan.
29. Mishra CS, Pratyush K, Sagadevan LDM, James J, Veettil AKT, Thankamani V, A comparative study on phytochemical screening and antibacterial activity of roots of Alstonia scholaris with the roots, leaves and stem bark. Int J Res Phytochem Pharmacol 2011; 1(2): 77-82.
30. Sofowra A, Medicinal Plants and Traditional Medicine in Africa. Ibadan, Nigeria: Spectrum Books Ltd 1993; 191- 289.
31. Trease GE, Evans WC, Pharmacognosy, 11th edn, London: Bailliere Tindall.1989; 45-50.
32. Geneva: WHO. WHO. Quality Control Method for Medicinal Plant Materials 2002.
33. Chase CR, Jr, Pratt R. Fluorescence of powdered vegetable drugs with particular reference to development of a system of identification. J Am Pharm Assoc Am Pharm Assoc 1949; 38: 324–31.
34. Alam F, Us Saqib QN. Pharmacognostic study and development of quality control parameters for fruit, bark and leaf of Zanthoxylum armatum (Rutaceae). Anc Sci Life 2015; 34(3):147-155.

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