Volume 2, Issue 2 (11-2020)                   Plant Biotechnol Persa 2020, 2(2): 38-42 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Salahvarzi S, Shakib P, Pirhadi M, Alikord M, Jahed Khaniki G. Helicobacter Phytotherapy: Medicinal Plants Affecting Helicobacter Pylori Infection in Iran. Plant Biotechnol Persa 2020; 2 (2) :38-42
URL: http://pbp.medilam.ac.ir/article-1-64-en.html
Department of Environmental Health, Food Safety Division, Faculty of Public Health, Tehran University of Medical Sciences, Tehran, Iran , m.pirhadi371@gmail.com
Abstract:   (961 Views)
Helicobacter pylori is a gram-negative, helical, and microaerophilic bacterium, and its infection affects the health of the community. This bacterium protects itself from stomach acid by having the enzyme urease. Nearly three decades after the discovery of this bacterium, no specific treatment regimen has been proposed that is able to eliminate the infection in all treated patients. Besides, the different treatment regimens with different effects on the pathogen have been proposed. Widespread use of antibiotics in treatment and eradication has led to the growth of antibiotic resistance. In this review study, the most important medicinal plants with inhibitory effect on Helicobacter pylori were reported. For this review study, keywords such as Helicobacter pylori, bacterial infection, medicinal plants, extract and Iran were used. The databases searched for in those articles were Google Scholar, SID, Scapus, PabMed, Science Direct, and ISI search engines. Plants such as Satureia hortensis L., Salvia officinalis, Mentha Piperita, Ziziphora tenuior, Mentha pulegium, Satureja khuzestanica, Thymus caramanicus, Thymus vulgaris, Zataria multiflora, Ocimum basilicum L, Salvia mirzayanii, Teucus frutus, Majus frutics, Rubus frutics Geum Iranicum, Filipendula ulmaria L, Glycyrrhiza glabra L., Citrus sinensis, Argentin anserine, Bunium persicum, Crataegus aronia, Cuminum cyminum L. and etc were assessed. These are the most important medicinal plants affecting Helicobacter pylori in Iran.
 
Full-Text [PDF 128 kb]   (532 Downloads)    
Type of Study: Letter to editor | Subject: Phytomedicine
Received: 2021/01/6 | Accepted: 2020/11/30 | Published: 2021/01/9

References
1. Abdollahi H, Savari M, Zahedi MJ, Darvish Moghadam S, Hayatbakhsh Abasi M. A study of rdxA gene deletion in metronidazole resistant and sensitive Helicobacter pylori isolates in Kerman, Iran. Jundishapur J Microbiol 2011, 4(2): 99-104.
2. Malaty HM, Graham DY. Importance of childhood socioeconomic status on the current prevalence of Helicobacter pylori infection, Gut, 1994, 35(6): 742-5.
3. Alarcon T, Domingo D, Lopez-brea M. Antibiotic resistance problems with Helicobacter pylori. Int J Antimicrob Agents 1999; 12(1):19-26.
4. Aminian K, Farsad F, Ghanbari A, Fakhreih S, Hasheminasab SM. A randomized trial comparing four Helicobacter pylori eradication regimens: standard triple therapy, ciprofloxacin based triple therapy, quadruple and sequential therapy. Trop Gastroenterol 2010; 31(4): 303-7.
5. Massarrat S, Saberi-Firoozi M, Soleimani A, Himmelmann GW, Hitzges M, Keshavarz H. Peptic ulcer disease, irritable bowel syndrome and constipation in two populations in Iran. Eur J Gastroenterol Hepatol 1995; 7: 427–33.
6. Graham DY., Lew GM., Kelin PD., Evans DG., Evans DJ Jr, Saeed ZA., et al. Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric or duodenal ulcer. A randomized, controlled study, Ann Intern Med, 1992, 116(9): 705-8.
7. Taylor JL., Zagari M., Murphy K., Freston JW. Pharmacoeconomic comparison of treatments for the eradication of Helicobacter pylori, Arch Intern Med, 1997, 157(1): 87-97.
8. Zullo A, Francesco V, Hassan C, Morini S, Vaira D.The sequential therapy regimen for Helicobacter pylori eradication: a pooled-data analysis. Gut 2007; 56: 1353–1357.
9. Bytzer P, O’Morain C. Treatment of Helicobacter pylori. Helicobacter 2005; 10 (Suppl 1): 40–6.
10. Egan BJ, Marzio L, O’Connor H, O’Morain C. Treatment of Helicobacter pylori infection. Helicobacter 2008; 13 (Suppl 1):35– 40.
11. Valadi A, Nasri S, Abbasi N, Amin GR. Antinociceptive and anti-inflammatory effects of hydroalchoholic extract of Anethum graveolens L. seed. Journal of Medicinal Plants 2010; 9(34):124-130.
12. Moayeri A, Azimi M, Karimi E, Aidy A, Abbasi N. Attenuation of Morphine Withdrawal Syndrome by Prosopis Farcta Extract and Its Bioactive Component Luteolin in Comparison with Clonidine in Rats. Med Sci Monitor Basic Res 2018; 24(9): 151-158.
13. Bahmani M, Taherikalani M, Khaksarian M, Rafieian-Kopaei M, Ashrafi B, Nazer M, Soroush S. Abbasi N, Rashidipour M. The synergistic effect of hydroalcoholic extracts of Origanum vulgare, Hypericum perforatum and their active components carvacrol and hypericin against Staphylococcus aureus. Future Science OA 2019; 5(3): Article number FSO371.
14. Abbasi N, Khosravi A, Aidy A, Shafiei M. Biphasic response to luteolin in MG-63 osteoblast-like cells under high glucose-induced oxidative stress. Iranian Journal of Medical Sciences 2016; 41(2): 118-125.
15. Bahmani M, Taherikalani M, Khaksarian M, Rafieian-Kopaei M, Ashrafi B, Nazer M, Soroush S. Abbasi N, Rashidipour M. The synergistic effect of hydroalcoholic extracts of Origanum vulgare, Hypericum perforatum and their active components carvacrol and hypericin against Staphylococcus aureus. Future Science OA 2019; 5(3): Article number FSO371.
16. Zangeneh MM, Ghaneialvar H, Akbaribazm M, Ghanimatdan M, Abbasi N, Goorani S, Pirabbasi E, Zangeneh A. Novel synthesis of Falcaria vulgaris leaf extract conjugated copper nanoparticles with potent cytotoxicity, antioxidant, antifungal, antibacterial, and cutaneous wound healing activities under in vitro and in vivo condition. Journal of Photochemistry and Photobiology B: Biology 2019; 197, art. no. 111556, .
17. Mahdavi B, Saneei S, Qorbani M, Zhaleh M, Zangeneh A, Zangeneh MM, Pirabbasi E, Abbasi N, Ghaneialvar H. Ziziphora clinopodioides Lam leaves aqueous extract mediated synthesis of zinc nanoparticles and their antibacterial, antifungal, cytotoxicity, antioxidant, and cutaneous wound healing properties under in vitro and in vivo conditions. Applied Organometallic Chemistry 2019; 33 (11), art. no. e5164.
18. Vítor JMB, Vale FF. Alternative therapies for Helicobacter pylori: Probiotics and phytomedicine. FEMS Immunology and Medical Microbiology. 2011; 63(2):153-64.
19. Erdogrul ÖT. Antibacterial activities of some plant extracts used in folk medicine. Pharmaceutical Biology. 2002; 40(4):269-73.
20. Moghaddam MN. In vitro inhibition of Helicobacter pylori by some spices and medicinal plants used in Iran. Global Journal of Pharmacology 2011; 5(3): 176- 180.
21. Nariman F., Eftekhar F., Habibi Z., Massarrat S., Malekzadeh R. Antibacterial activity of twenty Iranian plant extracts against clinical isolates of Helicobacter pylori. Iranian Journal of Basic Medical Sciences 2009; 12(2): 105-111.
22. Nourizadeh E., Mirzapour T., Gasemi K., Rezai M., Latifi N. Survey of anti-bacterial effects of spearmint, liquorice, perennial weed, mayweed and thyme on helicobacter pylori. Daneshvar Medicine 2004; 11(52): 67-71.
23. Motaharinia Y., Hazhir MS., Rezaee MA., Vahedi S., Rashidi A., Hosseini W., et al. Comparison of in vitro antimicrobial effect of ethanol extracts of Satureja khuzestanica, Rhus coriaria, and Ocimum basilicum L. on Helicobacter pylori. Journal of Medicinal Plants Research 2012; 6(21): 3749-3753.
24. Ghannadi A., Sajjadi S-E., Abedi D., Yousefi J., Daraei-Ardekani R. The in vitro activity of seven Iranian plants of the Lamiaceae family against Helicobacter pylori. Nigerian Journal of Natural Products and Medicine 2004; 8(1): 40-42.
25. Atapour M., Zahedi MJ., Mehrabani M., Safavi M., Keyvanfard V., Foroughi A., et al. In vitro susceptibility of the Gramnegative bacterium Helicobacter pylori to extracts of Iranian medicinal plants. Pharmaceutical Biology 2009; 47(1): 77-80.
26. Moghaddam MN., Karamoddin M-aK., Ramezani M. In vitro anti-bacterial activity of sweet basil fractions against Helicobacter pylori. Journal of Biological Sciences 2009; 9(3): 276-279.
27. Abachi S., Khademi F., Fatemi H., Malekzadeh F. Study of antibacterial activity of selected Iranian plant extracts on Helicobacter pylori. International of Organization of Science Research of Dental and Medical Science 2013; 5(1): 55-59.
28. Valifard M., Omidpanah N., Farshad S., Amin Shahidi M., Mohsenzadeh S., Farshad O. Antibacterial activity of extracts and essential oils of two iranian medicinal plants, Salvia mirzayanii and Zhumeria majdae, against Helicobacter pylori. Middle-East Journal of Scientific Research 2014; 19: 1001-1006.
29. Nakhaei M., Khaje-Karamoddin M., Ramezani M., Malekzadeh F. In vitro antibacterial activity of cumin (Cuminum cyminum L.) and tarragon (Artemisia dracunculus L.) extracts against clinical isolates of Helicobacter pylori. Scientific Information Database 2006; 9(3): 193-200.
30. Dehghan M., Noorizadeh E. Survey of anti-bacterial effects of turmeric, ginger, clove and cardamom on Helicobacter pylori. Journal of Ardabil University of Medical Sciences 2002; 2(2): 19-26.
31. Shirazi M., Fazeli M., Sultan Dallal M., Eshraghi S., Jamalifar H., Alamulhoda E. A comparative study on the antimicrobial effect of some medicinal herbal extracts and selective antibiotics against the clinical isolates of Helicobactor pylori. Journal of Medicinal Plants 2003; 3(7): 53-60.
32. Malekzadeh F., Ehsanifar H., Shahamat M., Levin M., Colwell R. Antibacterial activity of black myrobalan (Terminalia chebula Retz) against Helicobacter pylori. International journal of antimicrobial agents 2001; 18(1): 85-88.
33. Ghaedi M., Rezaee MA., Fakhari S., Ghorashi M., Pirmohamadi H., Doost RD., et al. Effects of ethanol extract of commiphora myrrha gum against Helicobacter pylori and inhibition of proliferation of the human AGS cell line in vitro. Journal of the Australian Traditional- Medicine Society 2014; 20(2): 106-111.
34. Nakhaei M., Khaje-Karamoddin M., Ramezani M. Inhibition of Helicobacter pylori growth in vitro by saffron (Crocus sativus L.). Iranian Journal of Basic Medical Sciences 2008; 11(2): 91-96.

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.