Prostatitis can occur at any age, after its enlargement, it puts pressure on the urinary tracts and causes urinary symptoms. Factors influencing the prevalence of prostatitis include age, genetic, diet, cancer, hormonal factors, and environmental factors. A microbial infection often causes prostatitis. In this systematic review, we tried to report the most important herbal medicines that have been mentioned for prostate treatment in Iranian ethnobotanical documents. Some keywords have been used, such as prostate, prostate inflammation, medicinal plants, ethnobotany, identification of medicinal plants. Also some Iranian Databases have been used, such as ISI Web Science, PubMed, Scopus, ISC, SID, and Google Scholar to review articles and resources. Ethnobotanical knowledge has a solution for treating this disease. Based on the results obtained in Iranian ethnobotanical documents, Lamium album L., Origanum vulgare, Silybum marianum (L.) Gaerth., Sorghum halepense (L.) Pers., Polygonum aviculare L., Urtica dioica L., Alhagi persarum Boiss. & Buhse., Eremurus persicus (Jaub. & Spach) Boiss., Gundelia tournefortii, Myrtus communis L., Tribulus Terrestris L., and Physalis divaricata D. Don are the most important herbal medicines used in Iranian ethnobotanical sources for prostate treatment. Aim of this systematic review, was to report the most important medicinal plants for prostatitis treatment mentioned in Iranian ethnobotanical documents.
