Dr Pegah Shahkib, Dr Mahmoud Bahmani, Dr Pouya Parsaee, Volume 2, Issue 2 (11-2020)
Abstract
Glycyrrhiza glabra L. is a valuable medicinal and nutritional plant of the Fabaceae family. In traditional medicine, it is used to treat duodenal ulcers, coughs, sore throats, inflammation, bloating, strong laxatives and antidotes, hot flashes, relieves thirst, relieves skin discomfort, and anti-allergies. The most important active ingredient in this plant is glycyrrhizic acid. G. glabra L. is a widely used plant in Iran and medicinal products have been produced from it in Iran. Interactions between herbal and chemical drugs are also common. In this review study, drug interactions between G. glabra L. and chemical corticosteroid drugs were investigated and reported. G. glabra L. can interact with a variety of chemical drugs, so concomitant use of G. glabra L. with other drugs requires caution.
AlliumSativum L. is a plant with different nutritional and medicinal principles. Despite the valuable medicinal effects that have been reported for the garlic plant, but drug interactions with chemical drugs have been reported. Garlic interacts with antihypertensive drugs, Saquinavir, hypoglycemics, general anesthetics, and anticoagulants, so associated use of garlic with mentioned chemical drugs should be used with caution to prevent drug interactions and side effects.
Matricaria recutita (Chamomile) is one of the most important and oldest medicinal plants known to man in the world. The main origin and center of the gene pool of this plant is the Mediterranean region, especially Iran. The aim of this study was to investigate the drug interaction of chamomile with routine chemical drugs. Consumption of chamomile with anticoagulants, sedatives, drugs requiring GI absorption, and iron supplementations causes drug interactions. Concomitant use of chamomile with these chemicals should be used with caution to prevent drug interactions and side effects.
