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Showing 2 results for Drug Resistance

Kimiya Karimi, Elahe Zarif Fakoor, Toktam Ziaee, Mahtab Mehboodi, Pouria Khodaei Ataloo, Masoud Sanati, Zeynab Mohammadi, Mohammadreza Dorzadeh, Kimia Rouzbeh, Reyhaneh Heshmati,
Volume 6, Issue 2 (7-2024)
Abstract

Streptococcus pyogenes is a pathogen of significant public health concern. It is the most common cause of bacterial pharyngitis and is responsible for serious conditions such as streptococcal toxic shock syndrome, necrotizing fasciitis, impetigo, and scarlet fever. Additionally, S. pyogenes is involved in post-streptococcal sequelae, including acute glomerulonephritis, acute rheumatic fever, rheumatic heart disease, and reactive arthritis. The increasing antibiotic resistance of S. pyogenes has led to a growing interest in exploring alternative treatments, such as medicinal plants, which may provide effective and safer options for preventing and treating diseases caused by this bacterium. Today, there is an increasing interest in medicinal plants due to less side effects, ease of use, availability, and usually affordability.  In conclusion, given the growing antibiotic resistance of Streptococcus pyogenes, this study investigates the inhibitory effects of medicinal plants against this pathogen. The aim is to assess the potential of these plants in preventing and treating diseases caused by S. pyogenes, as well as to elucidate their mechanisms of action on this bacterium.
 

Elahe Zarif Fakoor, Samad Rezvanimanesh, Shiva Ahmadishoar, Mahtab Mehboodi, Hamid Reza Mardani, Samad Rastmanesh, Mohammad Amin Niknejad, Rosita Yousefian Mobarekeh, Shiva Eskandari, Maede Shirazi, Behnam Poureslamfar,
Volume 6, Issue 2 (7-2024)
Abstract

This review meticulously examines the antimicrobial effects of medicinal plants on Staphylococcus aureus and underscores their potential in overcoming the challenge of drug resistance. With a plethora of plant species known for their antimicrobial properties, exploring alternative solutions to combat bacterial infections is imperative. The review emphasizes the importance of investigating plant-derived compounds that can effectively inhibit bacterial growth through unique mechanisms and discusses the synergistic effects of combining multiple compounds from plant extracts. Researchers are actively working on isolating novel bioactive chemicals from plants to serve as effective alternatives to traditional antibiotics. The study highlights the critical role of herbal medicines in addressing resistant strains of Staphylococcus aureus and stresses the necessity for further research to develop innovative treatment approaches.
 

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