logo
Volume 6, Issue 1 (6-2024)                   pbp 2024, 6(1): 88-92 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ranjbari A, Nazer M. A Review of Medicinal Plants Effective on Wound Healing in the Western Part of Iran Based on Ethnobotanical Documents. pbp 2024; 6 (1) :88-92
URL: http://pbp.medilam.ac.ir/article-1-225-en.html
1- Department of General Surgery, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
2- epartment of Infectious Diseases and Tropical Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran , nazer@med.mui.ac.ir
Abstract:   (316 Views)
Objective: The skin is a barrier between the human body and the external environment and protects the body against external chemical and physical factors. Despite major advances in wound treatment, wound healing remains one of the most important challenges ahead. Some medicinal plants with anti-inflammatory, antimicrobial and antioxidant properties are effective in healing and repairing wounds. The present study is a review of medicinal plants that are used in the ethnobotanical knowledge of western Iran for wound healing in skin wounds.
Methodology: In this study, the keywords of medicinal plants, wound healing, skin wound, West Azerbaijan, East Azerbaijan, Kurdistan, Kermanshah, Ilam, Khuzestan and ethnobotany were used to search for articles. The investigated databases were Google Scholar, SID, Megaran, PubMed, Scopus. Related ethnobotanical articles were used to review the texts.

Results: Based on the obtained results, it was determined that medicinal plants such as Sisymbrium sophia L, Fumaria officinalis L., Plantago major L., Alcea spp., Urtica spp., Astragalus gossypinus Fischer., Fumaria officinalis, Iperata cylindrica (L.), Polygonum aviculare L., Sanguisorba minor Scop., Alcea angulata, Aristolochia olivieri, Calendula persica, Citrullus colocynthis, Fumaria parviflora, Nerium oleander, Scrophularia striata, Allium schoenoprasum, Ixiolirion tataricum, Thymus Kotchyanous, Adonis aestivalis, Cardaria draba, Althaea officinalis, Beta vulgaris , Carthamus tinetorius L., Chrysanthemum coronarium, Helianthus annus L., Matricaria recutita L. and Vicia sativa are medicinal plants that heal wounds in these areas.

Conclusion: Medicinal plants and plant derivatives due to the presence of antioxidant compounds and secondary medicinal compounds such as tannins, anthocyanins, flavon, flavonoids, phenols and also less side effects than chemical drugs and species diversity in the treatment of skin wounds and Reports of their traditional effects in the treatment of wounds present them as an inexpensive and effective choice for wound healing. The need for more pharmacological and clinical studies to produce wound healing drugs seems necessary and necessary.
Full-Text [PDF 1716 kb]   (67 Downloads)    
Type of Study: Research | Subject: Herbal Drugs
Received: 2024/08/3 | Accepted: 2024/06/4 | Published: 2024/06/4

References
1. Wilkinson HN, Hardman MJ. Wound healing: cellular mechanisms and pathological outcomes. Open Biol. 2020 Sep 30;10(9):200223. doi:10.1098/rsob.200223.
2. Peña OA, Martin P. Cellular and molecular mechanisms of skin wound healing. Nat Rev Mol Cell Biol. 2024 Mar 25;1-8. doi:10.1038/s41573-024-00465-8.
3. Dong R, Guo B. Smart wound dressings for wound healing. Nano Today. 2021 Dec 1;41:101290. doi:10.1016/j.nantod.2021.101290.
4. Yazarlu O, Iranshahi M, Kashani HR, Reshadat S, Habtemariam S, Iranshahy M, Hasanpour M. Perspective on the application of medicinal plants and natural products in wound healing: A mechanistic review. Pharmacol Res. 2021 Dec;174:105841. doi:10.1016/j.phrs.2021.105841.
5. Sharma A, Khanna S, Kaur G, Singh I. Medicinal plants and their components for wound healing applications. Fut J Pharm Sci. 2021 Dec;7(1):1-3. doi:10.1016/j.fjps.2021.100091.
6. Vitale S, Colanero S, Placidi M, Di Emidio G, Tatone C, Amicarelli F, D’Alessandro AM. Phytochemistry and biological activity of medicinal plants in wound healing: an overview of current research. Molecules. 2022 Jun 1;27(11):3566. doi:10.3390/molecules27113566.
7. Albahri G, Badran A, Hijazi A, Daou A, Baydoun E, Nasser M, Merah O. The therapeutic wound healing bioactivities of various medicinal plants. Life. 2023 Jan 23;13(2):317. doi:10.3390/life13020317.
8. Porras G, Chassagne F, Lyles JT, Marquez L, Dettweiler M, Salam AM, Samarakoon T, Shabih S, Farrokhi DR, Quave CL. Ethnobotany and the role of plant natural products in antibiotic drug discovery. Chem Rev. 2020 Nov 9;121(6):3495-560. doi:10.1021/acs.chemrev.0c00416.
9. Moameri M, Abbasi Khalaki M, Dadjou F. Ethnobotany of Darwishchai-Sarein Watershed Plants with Medicinal and Food Approaches. 2020; 14 (4) :698-714.
10. Karimi, H., Taghi Maramzadeh, A., and Taghi Maramzadeh, A., 2020. A study on the diversity of medicinal plants in the Silvaneh region of Urmia in West Azerbaijan. The First National Conference on Challenges in Completing the Value Chain of Medicinal and Aromatic Plants, Urmia. Available at: [https://civilica.com/doc/1240344](https://civilica.com/doc/1240344).
11. Faraji, M., Dehdari, S., Shojaei, F., Kazemi, R., & Cheraghian, A. (2021). Collection and ethnobotanical study of medicinal plants in Hayatabad Majidi village, Behbahan County. 5th International Congress on the Development of Agriculture, Natural Resources, Environment, and Tourism in Iran, Tabriz. Retrieved from https://civilica.com/doc/1276160
12. Ghasemi PA, Momeni M, Bahmani M. Ethnobotanical study of medicinal plants used by Kurd tribe in Dehloran and Abdanan districts, Ilam province, Iran. African Journal of Traditional, Complementary and Alternative Medicines. 2013 Jan 18;10(2):368-85.
13. Moameri M, Abbasi Khalaki M, Dadjou F. Ethnobotany of Darwishchai-Sarein Watershed Plants with Medicinal and Food Approaches. 2020; 14 (4) :698-714
14. Derakhshan N, Khatamsaz M, Zolfaghari B. Ethnobotanical uses of plants in the Saghez (Kurdistan, Iran). jiitm 2017; 7 (4) :507-516
15. Karimi, H., Taghi Maramzadeh, A., & Taghi Maramzadeh, A. (2020). Study of the diversity of medicinal plants in the Silvana region of Urmia, West Azerbaijan. 1st National Conference on Challenges in Completing the Value Chain of Medicinal and Aromatic Plants, Urmia. Retrieved from https://civilica.com/doc/1240344
16. Khodayari, H., Amani, S., & Amiri, H. (2014). Ethnobotany of medicinal plants in northeastern Khuzestan Province. Retrieved from https://civilica.com/doc/1405826
17. Maleki-khezerlu S, Ansari-Ardali S, Maleki-khezerlu M. Ethno-Botanic Study and Traditional Use of Medicinal Plant of Ajabshir City. jiitm 2017; 7 (4) :499-506
18. Xu Z, Dong M, Yin S, Dong J, Zhang M, Tian R, Min W, Zeng L, Qiao H, Chen J. Why traditional herbal medicine promotes wound healing: Research from immune response, wound microbiome to controlled delivery. Adv Drug Deliv Rev. 2023 Apr 1;195:114764. doi:10.1016/j.addr.2022.114764.
19. Shanmugam S, Rajagopal V, Balamurugan S, Muthupandi CP, Eswaran VM, Raveendraretnam K, Rajendran K. Ethnobotanical indices on wound healing medicinal plants in the Arjuna river of Virudhunagar district in Tamil Nadu, Southern India. Asian J Ethnobiol. 2021 Mar 13;4(1). doi:10.46242/aje.2021.4.1.126.
20. Sharma A, Khanna S, Kaur G, Singh I. Medicinal plants and their components for wound healing applications. Fut J Pharm Sci. 2021 Dec;7(1):1-3. doi:10.1016/j.fjps.2021.100091. (Note: This entry is a duplicate of entry 5.)
21. Nigussie D, Makonnen E, Tufa TB, Brewster M, Legesse BA, Fekadu A, Davey G. Systematic review of Ethiopian medicinal plants used for their anti-inflammatory and wound healing activities. J Ethnopharmacol. 2021 Aug 10;276:114179. doi:10.1016/j.jep.2021.114179.
22. Nazir Y, Linsaenkart P, Khantham C, Chaitep T, Jantrawut P, Chittasupho C, Rachtanapun P, Jantanasakulwong K, Phimolsiripol Y, Sommano SR, Tocharus J. High efficiency in vitro wound healing of Dictyophora indusiata extracts via anti-inflammatory and collagen stimulating (MMP-2 inhibition) mechanisms. J Fungi. 2021 Dec 20;7(12):1100. doi:10.3390/jof7121100.
23. Akbari B, Baghaei-Yazdi N, Bahmaie M, Mahdavi Abhari F. The role of plant-derived natural antioxidants in reduction of oxidative stress. BioFactors. 2022 May;48(3):611-33. doi:10.1002/biof.1853.

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.