Standardization of Aloe-Emodin Compound in Aloe sinkatana Plant Extract Using TLC and UV-visible Spectroscopic Methods

Dawoud, Azza

doi:10.61186/pbp.7.3.6

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Dawoud A. Standardization of Aloe-Emodin Compound in Aloe sinkatana Plant Extract Using TLC and UV-visible Spectroscopic Methods. pbp 2025; 7 (3)
URL: http://pbp.medilam.ac.ir/article-1-274-en.html

Standardization of Aloe-Emodin Compound in Aloe sinkatana Plant Extract Using TLC and UV-visible Spectroscopic Methods

Azza Dawoud ^*

Assistant professor at Medicinal and Aromatic Plants & Traditional Medicine Research Institute, National Center of Research, Sudan. , azzadawoudhussien@gmail.com

Abstract: (353 Views)

Objectives: Aloe-emodin is one the of dynamic compounds and has several pharmacological activities such as anti-inflammatory, antitumor, antiviral, anticancer, antifungal antidiabetic, and antipsoriatic. It is an important ingredient in several traditional herbal formulations. This study was done for qualitative and quantitative standardization of the Aloe-Emodin compound in Aloe sinkatana plant extract.
Methods: TLC (Thin layer chromatography) and UV-visible spectroscopic methods were developed for both qualitative and quantitative standardization of aloe emodine in Aloe sinkatana plant extract.
Results: The results indicated that TLC and UV-visible spectroscopic methods are simple, accurate, sensitive, precise, and reproducible.
Conclusion: In conclusion, we can say that the TLC and UV-visible spectroscopic methods can be effectively used for standardizing aloe-emodin in various pharmaceutical dosage forms.

Keywords: Aloe-emodin, Aloe sinkatana plant, Standardization, Thin layer chromatography, and UV-visible spectroscopic.

Type of Study: Research | Subject: Bioactive Compounds
Received: 2025/01/16 | Accepted: 2025/02/1 | Published: 2025/01/29

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