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Hooshmand Garehbagh L, Tahmasebi M. A Review of Medicinal Plants Used for the Treatment of Hyperlipidemia: An Ethnobotanical Survey in Southern Iran. pbp 2025; 7 (3)
URL: http://pbp.medilam.ac.ir/article-1-285-en.html
URL: http://pbp.medilam.ac.ir/article-1-285-en.html
1- Department of Internal Medicine, School of Medicine, Imam Khomeini Hospital, Urmia University of Medical Sciences, Urmia, Iran & Department of Internal Medicine, School of Medicine, Imam Khomeini Hospital, Urmia University of Medical Sciences, Urmia, Iran , Laya.Hooshmand58@gmail.com
2- School of Medicine, Emam Khomeini Hospital, Ilam University of Medical Sciences, Ilam, Iran
2- School of Medicine, Emam Khomeini Hospital, Ilam University of Medical Sciences, Ilam, Iran
Abstract: (320 Views)
Objective: Hyperlipidemia refers to an abnormal increase in blood lipid levels, including elevated triglycerides and low-density lipoprotein cholesterol (LDL-C), commonly known as "bad cholesterol." This condition significantly increases the risk of cardiovascular diseases, stroke, and other serious health complications. The present ethnobotanical review aims to identify medicinal plants traditionally used for managing hyperlipidemia in the southern regions of Iran.
Methods: This review was conducted by systematically searching relevant articles using keywords such as medicinal plants, ethnobotany, hyperlipidemia, and the names of the southern Iranian provinces (Sistan and Baluchestan, Bushehr, Hormozgan, Khuzestan, Fars, and Kerman). Databases including Google Scholar, SID, Magiran, PubMed, and Scopus were examined to gather relevant literature. Ethnobotanical studies were selected and analyzed to identify medicinal plants associated with lipid-lowering effects.
Results: The findings revealed that several medicinal plants are traditionally employed in the ethnobotanical knowledge of southern Iran to manage hyperlipidemia. The most commonly reported species include Lepidium latifolium L., Cichorium intybus L., Achillea millefolium L., Silybum marianum (L.) Gaertn., Arum elongatum subsp. alpinariae Alpinar & R.R. Mill, Glycyrrhiza glabra L., Rheum ribes L., Amygdalus lycioides Spach, Amygdalus scoparia, Withania somnifera, Caralluma edulis, Rumex acetosa L., Coriandrum sativum, Allium sativum, Sesamum indicum, Anethum graveolens L., Anthriscus sylvestris, Gundelia tourneforti L., Tragopogon aureus Boiss, Trigonella foenum-graecum L., Solanum nigrum L., Phoenix dactylifera L., Achillea eriophora DC., Artemisia sieberi Besser, Bienertia cycloptera, and Teucrium polium L. Notably, plant leaves were the most frequently utilized plant part for their lipid-lowering properties.
Conclusion: This review highlights the extensive use of medicinal plants in the traditional knowledge of southern Iran for the management of hyperlipidemia. The widespread reliance on plant-based therapies underscores their potential as natural lipid-lowering agents. However, further pharmacological and clinical studies are essential to validate their efficacy and safety for therapeutic applications.
Methods: This review was conducted by systematically searching relevant articles using keywords such as medicinal plants, ethnobotany, hyperlipidemia, and the names of the southern Iranian provinces (Sistan and Baluchestan, Bushehr, Hormozgan, Khuzestan, Fars, and Kerman). Databases including Google Scholar, SID, Magiran, PubMed, and Scopus were examined to gather relevant literature. Ethnobotanical studies were selected and analyzed to identify medicinal plants associated with lipid-lowering effects.
Results: The findings revealed that several medicinal plants are traditionally employed in the ethnobotanical knowledge of southern Iran to manage hyperlipidemia. The most commonly reported species include Lepidium latifolium L., Cichorium intybus L., Achillea millefolium L., Silybum marianum (L.) Gaertn., Arum elongatum subsp. alpinariae Alpinar & R.R. Mill, Glycyrrhiza glabra L., Rheum ribes L., Amygdalus lycioides Spach, Amygdalus scoparia, Withania somnifera, Caralluma edulis, Rumex acetosa L., Coriandrum sativum, Allium sativum, Sesamum indicum, Anethum graveolens L., Anthriscus sylvestris, Gundelia tourneforti L., Tragopogon aureus Boiss, Trigonella foenum-graecum L., Solanum nigrum L., Phoenix dactylifera L., Achillea eriophora DC., Artemisia sieberi Besser, Bienertia cycloptera, and Teucrium polium L. Notably, plant leaves were the most frequently utilized plant part for their lipid-lowering properties.
Conclusion: This review highlights the extensive use of medicinal plants in the traditional knowledge of southern Iran for the management of hyperlipidemia. The widespread reliance on plant-based therapies underscores their potential as natural lipid-lowering agents. However, further pharmacological and clinical studies are essential to validate their efficacy and safety for therapeutic applications.
Received: 2025/03/8 | Accepted: 2025/01/29 | Published: 2025/01/29
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