Volume 7, Issue 4 And 16 (12-2025)
pbp 2025, 7(4 And 16): 0-0 |
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Asghari R. Phytotherapy in Breast Cancer: A Review of the Most Effective Medicinal Plants and Their Mechanisms of Action. pbp 2025; 7 (4 and 16)
URL: http://pbp.medilam.ac.ir/article-1-300-en.html
URL: http://pbp.medilam.ac.ir/article-1-300-en.html
Department of Internal Medicine, School of Medicine, Imam Khomeini Hospital, Urmia University of Medical Sciences, Urmia, Iran , rahimasghari@gmail.com
Abstract: (56 Views)
Objective: Breast cancer stands as one of the most prevalent malignancies affecting women worldwide. It is typically characterized by the emergence of a palpable mass or alterations in breast tissue architecture. A variety of factors—including genetic predisposition, hormonal imbalances, and environmental exposures—contribute to the development of this complex disease. Early detection and effective treatment remain pivotal to improving patient survival and enhancing quality of life. This review aims to identify and examine the most significant medicinal plants cited in Iranian traditional medicine as beneficial for breast cancer, while exploring their potential mechanisms in prevention and therapy.
Methods: A comprehensive literature search was conducted using keywords such as medicinal plants, traditional medicine, breast cancer, and Iran across prominent scientific databases including PubMed, Scopus, Web of Science, and Google Scholar. Additionally, authoritative texts and specialized encyclopedias were consulted.
Results: The review highlights a wide array of plants noted for their therapeutic potential, including thyme, rosemary, pennyroyal, ginger, fennel, garlic, grape, artemisia, purslane, chamomile, pinto bean, tomato, chickpea, onion, wheat, pomegranate, red apple, cherry, turmeric, flaxseed, borage, olive, yarrow, sweet violet, celery, chasteberry, licorice, turnip, oat, aloe vera, calendula, green tea, carrot, and red pepper. These plants exert their effects through various mechanisms, such as inhibiting tumor cell proliferation, inducing apoptosis, suppressing angiogenesis, and modulating inflammatory responses.
Conclusion: Existing evidence suggests that medicinal plants traditionally employed in Iranian medicine—due to their rich content of bioactive compounds—hold promise as complementary approaches in the prevention and management of breast cancer. Further clinical and experimental studies are warranted to pave the way for the development of safer and more efficacious therapeutic options.
Methods: A comprehensive literature search was conducted using keywords such as medicinal plants, traditional medicine, breast cancer, and Iran across prominent scientific databases including PubMed, Scopus, Web of Science, and Google Scholar. Additionally, authoritative texts and specialized encyclopedias were consulted.
Results: The review highlights a wide array of plants noted for their therapeutic potential, including thyme, rosemary, pennyroyal, ginger, fennel, garlic, grape, artemisia, purslane, chamomile, pinto bean, tomato, chickpea, onion, wheat, pomegranate, red apple, cherry, turmeric, flaxseed, borage, olive, yarrow, sweet violet, celery, chasteberry, licorice, turnip, oat, aloe vera, calendula, green tea, carrot, and red pepper. These plants exert their effects through various mechanisms, such as inhibiting tumor cell proliferation, inducing apoptosis, suppressing angiogenesis, and modulating inflammatory responses.
Conclusion: Existing evidence suggests that medicinal plants traditionally employed in Iranian medicine—due to their rich content of bioactive compounds—hold promise as complementary approaches in the prevention and management of breast cancer. Further clinical and experimental studies are warranted to pave the way for the development of safer and more efficacious therapeutic options.
Received: 2025/05/14 | Accepted: 2025/12/1 | Published: 2025/12/1
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