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Gharibi A, Niazvand F, Teimouri M, Aidy A. Evaluation the Effects of Medicinal Plants in the Zagros Mountains on the Reproductive System: A Systematic Review. pbp 2026; 8
URL: http://pbp.medilam.ac.ir/article-1-327-en.html
1- Student Research Committee, Ilam University of Medical Sciences, Ilam, Iran
2- Department of Anatomical Sciences, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran , niazvandf@gmail.com
3- Department of Anatomical Sciences, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
4- Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract:   (709 Views)
Objective: Infertility is a global challenge for couples and may arise from various factors. Studies have highlighted a link between oxidative stress and infertility, emphasizing the role of antioxidants in mitigating reproductive damage. Certain medicinal plants with antioxidant properties have traditionally been used for this purpose. This review focuses on the effects of Pistacia atlantica, Capparis spinosa, Matricaria chamomilla L., and Ferulago angulata, commonly found in Iran’s Zagros Mountains, on the reproductive system. This study systematically reviewed research on the effects of Zagros-native plant species on infertility, analyzing findings from multiple scientific databases using qualitative methods.
Methods: Indexed searches were conducted in Persian and English using the terms ((“Fertility” OR “Reproductive System” OR “Testis” OR “Oocyte” OR “Sexual hormone” OR “LH” OR “FSH” OR “Testosterone” OR “Semen”) AND (“Zagros Mountains” OR “Pistacia atlantica” OR “Baneh” OR “Matricaria chamomilla” OR “Chamomile” OR “Capparis spinosa” OR “Caper” OR “Legji” OR “Ferulago angulata” OR “Chavir”)) from 2000 to 29 December 2024 in PubMed, Scopus, ScienceDirect, Google Scholar, SID, and Magiran. Out of 342 initially screened articles, 51 were relevant, and 17 fully matched the inclusion criteria for detailed analysis.
Results: Most studies reviewed indicate positive effects of these plants on infertility-related parameters. However, a limited number of reports describe adverse effects at certain dosages.
Conclusion: Various extracts of these medicinal plants can enhance fertility by promoting healthy gamete production. Careful removal of unnecessary or toxic compounds, adherence to proper extraction methods, and appropriate dosing are essential to minimize potential side effects

 
Full-Text [PDF 635 kb]   (144 Downloads)    
Type of Study: Review/Systemtic review | Subject: Herbal Drugs
Received: 2025/08/8 | Accepted: 2025/09/3 | Published: 2025/12/1

References
1. Tamrakar SR, Bastakoti R. Determinants of Infertility in Couples. J Nepal Health Res Counc. 2019 Apr 28;17(1):85-89. doi: 10.33314/jnhrc.1827. PMID: 31110383.
2. Zaha I, Muresan M, Tulcan C, Huniadi A, Naghi P, Sandor M, Tripon R, Gaspar C, Klaudia-Melinda M, Sachelarie L, Stefan L. The Role of Oxidative Stress in Infertility. J Pers Med. 2023 Aug 15;13(8):1264. doi: 10.3390/jpm13081264. PMID: 37623514; PMCID: PMC10455473.
3. Kaltsas A. Oxidative Stress and Male Infertility: The Protective Role of Antioxidants. Medicina (Kaunas). 2023 Oct 4;59(10):1769. doi: 10.3390/medicina59101769. PMID: 37893487; PMCID: PMC10608597.)
4. Lai TC, Roychoudhury S, Cho CL. Oxidative Stress and Varicocele-Associated Male Infertility. Adv Exp Med Biol. 2022;1358:205-235. doi: 10.1007/978-3-030-89340-8_10. PMID: 35641872
5. Zeng X, Huang Q, Long SL, Zhong Q, Mo Z. Mitochondrial Dysfunction in Polycystic Ovary Syndrome. DNA Cell Biol. 2020 Aug;39(8):1401-1409. doi: 10.1089/dna.2019.5172. Epub 2020 Feb 20. PMID: 32077751.)
6. Jensen SJ. Oxidative stress and free radicals. Journal of Molecular Structure: J THEOCHEM. 2003 Dec 1;666:387-92. doi.:10.1016/j.theochem.2003.08.037
7. Agarwal A, Said TM. Oxidative stress, DNA damage and apoptosis in male infertility: a clinical approach. BJU international. 2005 Mar 1;95(4):503-7. doi.:10.1111/j.1464-410x.2005.05328.x
8. Cordiano R, Di Gioacchino M, Mangifesta R, Panzera C, Gangemi S, Minciullo PL. Malondialdehyde as a Potential Oxidative Stress Marker for Allergy-Oriented Diseases: An Update. Molecules. 2023 Aug 9;28(16):5979. doi: 10.3390/molecules28165979. PMID: 37630231; PMCID: PMC10457993..
9. Herrera DG, Yague AG, Johnsen-Soriano S, Bosch-Morell F, Collado-Morente L, Muriach M, Romero FJ, Garcia-Verdugo JM. Selective impairment of hippocampal neurogenesis by chronic alcoholism: protective effects of an antioxidant. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7919-24. doi: 10.1073/pnas.1230907100. Epub 2003 Jun 5. PMID: 12792022; PMCID: PMC164688.
10. Antonio-García MT, Massó-Gonzalez EL. Toxic effects of perinatal lead exposure on the brain of rats: involvement of oxidative stress and the beneficial role of antioxidants. Food Chem Toxicol. 2008 Jun;46(6):2089-95. doi: 10.1016/j.fct.2008.01.053. Epub 2008 Feb 23. PMID: 18417264.
11. Tremellen K. Oxidative stress and male infertility--a clinical perspective. Hum Reprod Update. 2008 May-Jun;14(3):243-58. doi: 10.1093/humupd/dmn004. Epub 2008 Feb 14. PMID: 18281241.
12. Steiner AZ, Hansen KR, Barnhart KT, Cedars MI, Legro RS, Diamond MP, Krawetz SA, Usadi R, Baker VL, Coward RM, Huang H, Wild R, Masson P, Smith JF, Santoro N, Eisenberg E, Zhang H; Reproductive Medicine Network. The effect of antioxidants on male factor infertility: the Males, Antioxidants, and Infertility (MOXI) randomized clinical trial. Fertil Steril. 2020 Mar;113(3):552-560.e3. doi: 10.1016/j.fertnstert.2019.11.008. Epub 2020 Feb 25. PMID: 32111479; PMCID: PMC7219515.
13. Hussain T, Kandeel M, Metwally E, Murtaza G, Kalhoro DH, Yin Y, Tan B, Chughtai MI, Yaseen A, Afzal A, Kalhoro MS. Unraveling the harmful effect of oxidative stress on male fertility: A mechanistic insight. Front Endocrinol (Lausanne). 2023 Feb 13;14:1070692. doi: 10.3389/fendo.2023.1070692. PMID: 36860366; PMCID: PMC9968806.
14. Sikka SC, Rajasekaran M, Hellstrom WJ. Role of oxidative stress and antioxidants in male infertility. J Androl. 1995 Nov-Dec;16(6):464-8. PMID: 8867595.
15. Gharagozloo P, Aitken RJ. The role of sperm oxidative stress in male infertility and the significance of oral antioxidant therapy. Hum Reprod. 2011 Jul;26(7):1628-40. doi: 10.1093/humrep/der132. Epub 2011 May 5. PMID: 21546386.
16. Agarwal A, Said TM. Oxidative stress, DNA damage and apoptosis in male infertility: a clinical approach. BJU Int. 2005 Mar;95(4):503-7. doi: 10.1111/j.1464-410X.2005.05328.x. PMID: 15705068.
17. Kabodmehri R, Javaheri FSH, Alami F, Mahmoudi Z, Amjadi A, Saeedirad Z, Omidi S, Sadeghi S, Hoseini MSM, Mohamadiyan Z, Salimi Z, Shafaei H, Rasekhmagham R, Sharami SH, Karimian M, Karimi H, Doaei S. Female infertility and dietary antioxidant index (DAI); a case-control study. BMC Womens Health. 2023 Nov 16;23(1):608. doi: 10.1186/s12905-023-02747-9. PMID: 37974175; PMCID: PMC10655436.
18. Ashok A, Gupta S, Malhotra N, Sharma D. Oxidative stress and its role in female infertility and assisted reproduction: clinical implications. International Journal of Fertility and Sterility. 2009 Feb 1;2(4):147-64. doi: 10.22074/IJFS.2009.45727
19. Pourmasumi S, Sabeti P. Pistachio Antioxidants Can Decrease Negative Effects of Free Radicals on Male Reproductive System: An Assessment and Review. Pistachio and Health Journal. 2019 Jun 1;2(2):42-56. doi: 10.22123/PHJ.2020.220573.1041
20. Karbalaye, Ahmad & Lukhtanov, Vladimir. (2024). Three new species of the genus Polyommatus Latreille, 1804 (subgenus Agrodiaetus Hübner, [1822]) from the Central Zagros Mountains, Iran (Lepidoptera, Lycaenidae, Polyommatinae). J Ecologica Montenegrina. 78. 119-133. 10.37828/em.2024.78.13.doi: 10.37828/em.2024.78.13
21. Elyasi Ghahfarrokhi A, Saeedi M, Mojtabavi S, Kobarfard F, Faramarzi MA. Chemical composition and biological effects of Pistacia atlantica Desf. oleoresin essential oil. J Research of Pharmacognosy. 2022 Jul 1;9(3):25-33. doi: 10.22127/RJP.2022.326106.1830
22. Tolooei M, Mirzaei A. Effects of Pistacia Atlantica Extract on Erythrocyte Membrane Rigidity, Oxidative Stress, and Hepatotoxicity Induced by CCl4 in Rats. Glob J Health Sci. 2015 Mar 26;7(7 Spec No):32-8. doi: 10.5539/gjhs.v7n7p32. PMID: 26153201; PMCID: PMC4803997.
23. Lim TK. Matricaria chamomilla. InEdible Medicinal and Non-Medicinal Plants: Volume 7, Flowers 2013 Sep 3 (pp. 397-431). Dordrecht: Springer Netherlands.
24. Singh O, Khanam Z, Misra N, Srivastava MK. Chamomile (Matricaria chamomilla L.): An overview. Pharmacogn Rev. 2011 Jan;5(9):82-95. doi: 10.4103/0973-7847.79103. PMID: 22096322; PMCID: PMC3210003.
25. El Mihyaoui A, Esteves da Silva JCG, Charfi S, Candela Castillo ME, Lamarti A, Arnao MB. Chamomile (Matricaria chamomilla L.): A Review of Ethnomedicinal Use, Phytochemistry and Pharmacological Uses. Life (Basel). 2022 Mar 25;12(4):479. doi: 10.3390/life12040479. PMID: 35454969; PMCID: PMC9032859.
26. Rafraf M, Zemestani M, Asghari-Jafarabadi M. Effectiveness of chamomile tea on glycemic control and serum lipid profile in patients with type 2 diabetes. J Endocrinol Invest. 2015 Feb;38(2):163-70. doi: 10.1007/s40618-014-0170-x. Epub 2014 Sep 7. PMID: 25194428.
27. Asgharzade S, Rabiei Z, Rafieian-Kopaei M. Effects of Matricaria chamomilla extract on motor coordination impairment induced by scopolamine in rats. J Asian Pacific of Tropical Biomedicine. 2015 Oct 1;5(10):829-33. doi:10.1016/j.apjtb.2015.06.006
28. Khorasani F, Aryan H, Sobhi A, Aryan R, Abavi-Sani A, Ghazanfarpour M, Saeidi M, Rajab Dizavandi F. A systematic review of the efficacy of alternative medicine in the treatment of nausea and vomiting of pregnancy. J Obstet Gynaecol. 2020 Jan;40(1):10-19. doi: 10.1080/01443615.2019.1587392. Epub 2019 Jun 19. PMID: 31215276.
29. Bayliak MM, Dmytriv TR, Melnychuk AV, Strilets NV, Storey KB, Lushchak VI. Chamomile as a potential remedy for obesity and metabolic syndrome. EXCLI J. 2021 Jul 26;20:1261-1286. doi: 10.17179/excli2021-4013. PMID: 34602925; PMCID: PMC8481792.
30. Afrigan L, Jafari Anarkooli I, Sohrabi D, Abdanipour A, Yazdinezhad A, Sayyar Z, Ghorbanlou M, Arianmanesh M. The effect of hydroethanolic extract of Matricaria chamomilla on the reproductive system of male rats exposed to formaldehyde. Andrologia. 2019 Oct;51(9):e13362. doi: 10.1111/and.13362. Epub 2019 Jul 19. PMID: 31321807.
31. Panico AM, Cardile V, Garufi F, Puglia C, Bonina F, Ronsisvalle G. Protective effect of Capparis spinosa on chondrocytes. Life Sci. 2005 Sep 30;77(20):2479-88. doi: 10.1016/j.lfs.2004.12.051. PMID: 15946691.
32. Allaith AA. Assessment of the antioxidant properties of the caper fruit (Capparis spinosa L.) from Bahrain. J Association of Arab Universities for Basic and Applied Sciences. 2016 Feb 1;19(1):1-7. doi:10.1016/j.jaubas.2014.07.001
33. Zarei M, Seyedi N, Maghsoudi S, Nejad MS, Sheibani H. Green synthesis of Ag nanoparticles on the modified graphene oxide using Capparis spinosa fruit extract for catalytic reduction of organic dyes. Inorganic Chemistry Communications. 2021 Jan 1;123:108327. doi:10.1016/j.inoche.2020.108327
34. Vahid H, Rakhshandeh H, Ghorbani A. Antidiabetic properties of Capparis spinosa L. and its components. Biomed Pharmacother. 2017 Aug;92:293-302. doi: 10.1016/j.biopha.2017.05.082. PMID: 28551550.
35. Mehrzadi S, Mirzaei R, Heydari M, Sasani M, Yaqoobvand B, Huseini HF. Efficacy and Safety of a Traditional Herbal Combination in Patients with Type II Diabetes Mellitus: A Randomized Controlled Trial. J Diet Suppl. 2021;18(1):31-43. doi: 10.1080/19390211.2020.1727076. Epub 2020 Feb 21. PMID: 32081056.
36. Sun Y, Yang T, Wang C. Capparis spinosa L. as a potential source of nutrition and its health benefits in foods: A comprehensive review of its phytochemistry, bioactivities, safety, and application. Food Chem. 2023 May 30;409:135258. doi: 10.1016/j.foodchem.2022.135258. Epub 2022 Dec 20. PMID: 36587515.
37. Gull T, Anwar F, Sultana B, Alcayde MA, Nouman W. Capparis species: A potential source of bioactives and high-value components: A review. Industrial crops and products. 2015 May 1;67:81-96. doi: 10.1016/j.indcrop.2014.12.059
38. Arslan R, Bektas N, Ozturk Y. Antinociceptive activity of methanol extract of fruits of Capparis ovata in mice. J Ethnopharmacol. 2010 Aug 19;131(1):28-32. doi: 10.1016/j.jep.2010.05.060. Epub 2010 Jun 4. PMID: 20595018.
39. Tir M, Feriani A, Labidi A, Mufti A, Saadaoui E, Nasri N, Khaldi A, El Cafsi M, Tlili N. Protective effects of phytochemicals of Capparis spinosa seeds with cisplatin and CCl4 toxicity in mice. Food Bioscience. 2019 Apr 1;28:42-8. doi: 10.1016/j.fbio.2019.01.002
40. Huseini HF, Hasani-Rnjbar S, Nayebi N, Heshmat R, Sigaroodi FK, Ahvazi M, Alaei BA, Kianbakht S. Capparis spinosa L. (Caper) fruit extract in treatment of type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Complement Ther Med. 2013 Oct;21(5):447-52. doi: 10.1016/j.ctim.2013.07.003. Epub 2013 Aug 7. PMID: 24050578.
41. Bagherifar S, Sourestani MM, Zolfaghari M, Mottaghipisheh J, Zomborszki ZP, Csupor D. Variation of Chemical Constituents and Antiradical Capacity of Nine Ferulago angulata Populations from Iran. Chem Biodivers. 2019 Oct;16(10):e1900302. doi: 10.1002/cbdv.201900302. Epub 2019 Sep 12. PMID: 31415713.
42. Ghasemi Pirbalouti A, Momeni M, Bahmani M. Ethnobotanical study of medicinal plants used by Kurd tribe in Dehloran and Abdanan Districts, Ilam Province, Iran. Afr J Tradit Complement Altern Med. 2012 Dec 31;10(2):368-85. doi: 10.4314/ajtcam.v10i2.24. PMID: 24146463; PMCID: PMC3746586.
43. Naderi N, Hajian M, Souri M, Nasr Esfahani MH, Vash NT. Ferulago angulata extract improves the quality of buck spermatozoa post-thaw and counteracts the harmful effects of diazinon and lead. Cryobiology. 2021 Feb;98:17-24. doi: 10.1016/j.cryobiol.2021.01.008. Epub 2021 Jan 16. PMID: 33460590.
44. Chamkouri N, Koolivand Z, Niazvand F, Mojaddami A. Phytochemical analysis, characterization, and biosynthesis of gold nanoparticles, zinc oxide nanoparticles, and gold-zinc oxide nanocomposites from phoenix dactylifera L. seeds: Biological evaluation. Inorganic Chemistry Communications. 2023 Oct 1;156:111146.. doi:10.1016/j.inoche.2023.111146
45. Ghasemi Pirbalouti A. Chemical composition of the essential oils from the leaves and flowers of two Achillea species from Iran. Journal of Essential Oil Bearing Plants. 2017 Jan 2;20(1):205-14. doi: 10.1080/0972060X.2017.1282842
46. Ghasemi Pirbalouti A, Izadi A, Malek Poor F, Hamedi B. Chemical composition, antioxidant and antibacterial activities of essential oils from Ferulago angulata. Pharm Biol. 2016 Nov;54(11):2515-2520. doi: 10.3109/13880209.2016.1162816. Epub 2016 Apr 22. PMID: 27102982..
47. Huang D, Ou B, Prior RL. The chemistry behind antioxidant capacity assays. J Agric Food Chem. 2005 Mar 23;53(6):1841-56. doi: 10.1021/jf030723c. PMID: 15769103.
48. Pirbalouti AG, Ghahfarokhi BB, Ghahfarokhi SA, Malekpoor F. Chemical composition of essential oils from the aerial parts and underground parts of Iranian valerian collected from different natural habitats. Industrial Crops and Products. 2015 Jan 1;63:147-51. doi;10.1016/j.indcrop.2014.10.017
49. Ben Ahmed Z, Yousfi M, Viaene J, Dejaegher B, Demeyer K, Heyden YV. Four Pistacia atlantica subspecies (atlantica, cabulica, kurdica and mutica): A review of their botany, ethnobotany, phytochemistry and pharmacology. J Ethnopharmacol. 2021 Jan 30;265:113329. doi: 10.1016/j.jep.2020.113329. Epub 2020 Sep 1. PMID: 32889035.
50. Chauhan R, Singh S, Kumar V, Kumar A, Kumari A, Rathore S, Kumar R, Singh S. A Comprehensive Review on Biology, Genetic Improvement, Agro and Process Technology of German Chamomile (Matricaria chamomilla L.). Plants (Basel). 2021 Dec 23;11(1):29. doi: 10.3390/plants11010029. PMID: 35009033; PMCID: PMC8747680..
51. Nabavi SF, Maggi F, Daglia M, Habtemariam S, Rastrelli L, Nabavi SM. Pharmacological Effects of Capparis spinosa L. Phytother Res. 2016 Nov;30(11):1733-1744. doi: 10.1002/ptr.5684. Epub 2016 Jul 13. PMID: 27406313.
52. Norasteh H, Mohammadi S, Nikravesh MR, Boroumand-Noughabi S, Beheshti F. Effects of bene (pistacia atlantica) on histopathology of testis, sperm chromatin quality and stress oxidative in busulfan-induced infertile mice. Pharmaceutical Sciences. 2019 Mar 18;25(1):24-30.doi: 10.15171/PS.2019.4
53. Dogani M, Askari N, Hesari AK. A diet enriched with Pistacia atlantica fruits improves the female rats' reproductive system. J Tradit Complement Med. 2023 Nov 28;14(3):335-342. doi: 10.1016/j.jtcme.2023.09.004. PMID: 38707920; PMCID: PMC11068987.
54. Dogani M, Askari N, Kalantari-Hesari A, Hosseini Rahbar F. The effects of P. atlantica as a libido booster and sexual enhancer on the reproductive system of male rats. J Tradit Complement Med. 2021 Sep 25;12(4):345-353. doi: 10.1016/j.jtcme.2021.09.007. PMID: 35747351; PMCID: PMC9209825.
55. Behmanesh MA, Poormoosavi SM, Pareidar Y, Ghorbanzadeh B, Mahmoodi-Kouhi A, Najafzadehvarzi H. Pistacia atlantica's effect on ovary damage and oxidative stress in streptozotocin-induced diabetic rats. JBRA Assist Reprod. 2021 Feb 2;25(1):28-33. doi: 10.5935/1518-0557.20200044. PMID: 32569454; PMCID: PMC7863088.
56. Farideh ZZ, Bagher M, Ashraf A, Akram A, Kazem M. Effects of chamomile extract on biochemical and clinical parameters in a rat model of polycystic ovary syndrome. J Reprod Infertil. 2010 Oct;11(3):169-74. PMID: 23926485; PMCID: PMC3719301.
57. Ashtari A, Niazvand F, Chamkouri N, Mohammadi A, Karami AB. The ameliorative effects of Alpinia officinarum rhizome hydroalcoholic extract on cisplatin-induced testicular toxicity in rats. JBRA Assist Reprod. 2023 Mar 30;27(1):41-48. doi: 10.5935/1518-0557.20220017. PMID: 36098454; PMCID: PMC10065779.
58. Shoorei H, Khaki A, Ainehchi N, Hassanzadeh Taheri MM, Tahmasebi M, Seyedghiasi G, Ghoreishi Z, Shokoohi M, Khaki AA, Abbas Raza SH. Effects of Matricaria chamomilla Extract on Growth and Maturation of Isolated Mouse Ovarian Follicles in a Three-dimensional Culture System. Chin Med J (Engl). 2018 Jan 20;131(2):218-225. doi: 10.4103/0366-6999.222324. PMID: 29336372; PMCID: PMC5776854.
59. Afrigan L, Jafari Anarkooli I, Sohrabi D, Abdanipour A, Yazdinezhad A, Sayyar Z, Ghorbanlou M, Arianmanesh M. The effect of hydroethanolic extract of Matricaria chamomilla on the reproductive system of male rats exposed to formaldehyde. Andrologia. 2019 Oct;51(9):e13362. doi: 10.1111/and.13362. Epub 2019 Jul 19. PMID: 31321807.
60. Johari H, Sharifi E, Mardan M, Kafilzadeh F, Hemayatkhah V, Kargar H, Nikpoor N. The effects of a hydro alcoholic extract of matricaria chamomilla flower on the pituitary-gonadal axis and ovaries of rats. International Journal of Endocrinology and Metabolism : Volume 9, Issue 2, 2011 , Pages 330-334. doi: 10.5812/kowsar.1726913X.1822
61. Afiat M, Akbari Lor A, Najaf Najafi M, Ghazanfarpour M, Jafarabadi M. Examining the Effect of Chamomile on Clinical Symptoms and Hormonal Parameters Among Patients With Polycystic Ovarian Syndrome. J Family Reprod Health. 2022 Dec;16(4):248-253. doi: 10.18502/jfrh.v16i4.11355. PMID: 37465426; PMCID: PMC10350545.
62. Khojasteh Rad M, Ghani A, Ghani E. In vitro effects of Capparis spinosa L. extract on human sperm function, DNA fragmentation, and oxidative stress. J Ethnopharmacol. 2021 Apr 6;269:113702. doi: 10.1016/j.jep.2020.113702. Epub 2020 Dec 17. PMID: 33340598.
63. Al-mously SA, Gatea FK, Jawad EN, Qasim B. The effect of Capparis spinosa extract on induced PCOS mice. Int. J. Pharm. Res. 2020 Jul 2;12(2). doi: 10.31838/ijpr/2020.SP2.326
64. Mohammadi, J., Chatrroz, B., Delaviz, H. The Effect of Hydroalcoholic Extract of Capparis Spinosa on Quality of Sperm and Rate of Testosterone Following Induction of Diabetes in Rats. Journal of Isfahan Medical School, 2014; 31(264): 2042-2057. doi: 10.1113/and.13762
65. Mohammadi J, Chatrroz B, Delaviz H. The Effect of Hydroalcoholic Extract of Capparis Spinosa on Quality of Sperm and Rate of Testosterone Following Induction of Diabetes in Rats. J Isfahan Med Sch 2014; 31(264): 2042-52 doi: 10.1016/j.2010.05.
66. Nassab GR, Bohlouli S, Ghanbari A. Therapeutic effect of Ferulago angulata extract on reproductive parameters and serum testosterone levels in diabetic male Rats. JRPS. 2018 Jan 1;7(1):1-8. doi: 10.4103/0366-39.22124
67. Karimfar MH, Niazvand F, Haghani K, Ghafourian S, Shirazi R, Bakhtiyari S. The protective effects of melatonin against cryopreservation-induced oxidative stress in human sperm. Int J Immunopathol Pharmacol. 2015 Mar;28(1):69-76. doi: 10.1177/0394632015572080. PMID: 25816408.
68. Ganjiani V, Ahmadi N, Sharifiyazdi H, Meimandi-Parizi A, Mootabi-Alavi A, Hassanpour M, Mavalizadeh L. Ferulago angulata: A Complementary Therapy in Testicular Torsion–Detorsion Damage. Iran J Vet Surg. 2023 Apr 1;18(1):18-27. doi: 10.30500/ivsa.2022.357806.1319
69. Naderi N, Souri M, Nasr Esfahani MH, Hajian M, Tanhaei Vash N. Ferulago angulata extract ameliorates epididymal sperm toxicity in mice induced by lead and diazinon. Andrology. 2020 May;8(3):706-718. doi: 10.1111/andr.12730. Epub 2020 Jan 5. PMID: 31747138.
70. Naderi N, Souri M, Nasr-Esfahani MH, Hajian M, Nazem MN. Ferulago angulata extract alleviates testicular toxicity in male mice exposed to diazinon and lead. Tissue Cell. 2023 Dec;85:102257. doi: 10.1016/j.tice.2023.102257. Epub 2023 Oct 29. PMID: 37924715.

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