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Akbary kordlar A, Soleimani A. Native Iranian Medicinal Plants with Adverse Effects on Pregnancy and the Fetus: A Review. pbp 2026; 8
URL: http://pbp.medilam.ac.ir/article-1-330-en.html
URL: http://pbp.medilam.ac.ir/article-1-330-en.html
1- Gynecologist, Urmia University of Medical Sciences, Urmia, Iran , Dr.amak8181@gmail.com
2- Department of Cardiology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
2- Department of Cardiology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
Abstract: (309 Views)
Objective: The use of medicinal plants during pregnancy has increased due to traditional beliefs and their accessibility and affordability. However, certain plants may pose serious risks, including toxic effects on maternal health and fetal development. This review aims to identify medicinal plants with potential adverse effects on pregnant women and their unborn children.
Methodology: A comprehensive literature search was conducted across multiple scientific databases, including Google Scholar, SID, ISC, PubMed, Chemical Abstracts, and MagIran. Keywords such as “medicinal plants,” “pregnancy,” “fetal teratogenicity,” and “side effects” were used in both Persian and English to capture relevant studies.
Results: Several medicinal plants were identified as having notable toxic or teratogenic effects, including Aloe vera, pennyroyal, cayenne pepper, lily of the valley, senna, rue, licorice, saffron, Zingiber officinale (ginger), Matricaria chamomilla (chamomile), Mentha piperita (peppermint), Origanum vulgare (marjoram), Polygonum multiflorum, Borago officinalis (borage), Ricinus communis (castor), Foeniculum vulgare (fennel), Anethum graveolens (dill), Vitex agnus-castus, Ocimum basilicum (basil), Rheum palmatum, and Prunus serotina. These plants have been linked to congenital anomalies and complications during pregnancy.
Conclusion: Given these risks, careful and informed use of medicinal plants during pregnancy is essential. Healthcare professionals should educate expectant mothers about potential hazards and provide guidance to minimize adverse outcomes for both mother and fetus.
Methodology: A comprehensive literature search was conducted across multiple scientific databases, including Google Scholar, SID, ISC, PubMed, Chemical Abstracts, and MagIran. Keywords such as “medicinal plants,” “pregnancy,” “fetal teratogenicity,” and “side effects” were used in both Persian and English to capture relevant studies.
Results: Several medicinal plants were identified as having notable toxic or teratogenic effects, including Aloe vera, pennyroyal, cayenne pepper, lily of the valley, senna, rue, licorice, saffron, Zingiber officinale (ginger), Matricaria chamomilla (chamomile), Mentha piperita (peppermint), Origanum vulgare (marjoram), Polygonum multiflorum, Borago officinalis (borage), Ricinus communis (castor), Foeniculum vulgare (fennel), Anethum graveolens (dill), Vitex agnus-castus, Ocimum basilicum (basil), Rheum palmatum, and Prunus serotina. These plants have been linked to congenital anomalies and complications during pregnancy.
Conclusion: Given these risks, careful and informed use of medicinal plants during pregnancy is essential. Healthcare professionals should educate expectant mothers about potential hazards and provide guidance to minimize adverse outcomes for both mother and fetus.
Received: 2025/03/10 | Accepted: 2025/11/8 | Published: 2025/12/1
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