Volume 2, Issue 2 (11-2020)                   pbp 2020, 2(2): 21-23 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Farhad N, Shahsavari S. Probiotics and their effects in reduction hyperlipidemia. pbp 2020; 2 (2) :21-23
URL: http://pbp.medilam.ac.ir/article-1-53-en.html
1- Department of Pathology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran , leilazarei652@yahoo.com
2- Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran
Abstract:   (1656 Views)
Hyperlipidemia is a chronic condition but in many cases it may be reversed by a healthy diet and regular exercise. It is also associated to metabolic syndrome, diabetes, and obesity. Hyperlipidemia is known as one of the risk factors for coronary vessels disease, peripheral artery disease, and cardiac arrest. Drug-therapy is a usual method for treating hyperlipidemia. Consumption of probiotics may improve this problem and reduce the course of disease as well as its signs. The purpose of this review is to assess clinical evidences associating to role and effects of probiotics on the hl. Probiotics have greater influence on persons who suffer from high cholesterol. In the intestine, probiotics can bind to cholesterol and prevent its ingestion. Furthermore, they help in production of some biliary acids which play role in lipid and cholesterol metabolism. Some probiotics can produce short chain fatty acids that prevent formation of cholesterol in the liver. Probiotics are effective factors in reduction of hl.
Full-Text [PDF 147 kb]   (973 Downloads)    
Type of Study: Research |
Received: 2020/04/7 | Accepted: 2020/08/25 | Published: 2020/11/25

References
1. World Health Organization (WHO). Cardiovascular disease (CVDs) 2009. www.who.int/mediacentre/factsheets/fs317/en/index.html (accessed 30 December 2010).
2. World Health Organization Statistical Information System (WHOSIS) 2009. Statistical Information System. www.who.int/whosis/en/ (accessed 30 December 2010).
3. Athyros VG, Tziomalos K, Karagiannis A, Mikhailidis DP. Dyslipidaemia of obesity, metabolic syndrome and type 2 diabetes mellitus: the case for residual risk reduction after statin treatment. The Open Cardiovascular Medicine Journal. 2011; 5:24–34.
4. Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics-2013 update: a Report from the American Heart Association. Circulation. 2013; 127(1):p. e6-e245.
5. Kusters DM, Avis HJ, Braamskamp MJ, et al. Inheritance pattern of familial hypercholesterolemia and markers of cardiovascular risk. Journal of Lipid Research. 2013; 54(9):2543–2549.
6. Talmud PJ, Shah S, Whittall R, et al. Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study. The Lancet. 2013; 381(9874):1293–1301.
7. Goldstein JL, Schrott HG, Hazzard WR, Bierman EL, Motulsky AG. Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia. The Journal of Clinical Investigation.
8. Fredrickson DS, Levy RI, Lees RS. Fat transport in lipoproteins—an integrated approach to mechanisms and disorders. The New England Journal of Medicine. 1967; 276(1):34–42.
9. Toth PP. Drug treatment of hyperlipidaemia: a guide to the rational use of lipid-lowering drugs. Drugs. 2010; 70(11):1363–1379.
10. Mortazavian AM, Razavi SH, Ehsani M, Sohrabvandi S. Principles and methods of microencapsulation of probiotic microorganisms. Iran J Biotechnol 2007; 5 (1): 1-18.
11. Vinderola CG, Reinheimer JA. Enumeration of Lactobacilllus casei in the presence of l. acidophilus, bifidobacteria and lactic starter bacteria in fermented dairy products. Int Dairy J 2000; 10: 271-275.
12. Mortazavian AM, Ehsani MR, Mousavi SM, Reinheimer JA, Sohrabvandi S, et al. Preliminary investigation of the combined effect of heat treatment and incubation temperature on the viability of the probiotic micro- organisms in freshly made yogurt. Int J Dairy Tech 2006; 59 (1).
13. Mortazavian A, Sohrabvandi S. A textbook of review of probiotic and probiotic products. 1th ed. Tehran: Ata publisher; 1385. P. 48.
14. Kadooka Y, Sato M, Imaizumi K, Ogawa A, Ikuyama K, Akai Y, et al. Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial. European journal of clinical nutrition. 2010; 64(6):636-43.
15. Sharafedtinov KK, Plotnikova OA, Alexeeva RI, Sentsova TB, Songisepp E, Stsepetova J, et al. Hypocaloric diet supplemented with probiotic cheese improves body mass index and blood pressure indices of obese hypertensive patients-A randomized double-blind placebo-controlled pilot study. Nutrition journal. 2013; 12(1):138-48.
16. Chang B, Park S, Jang Y, Ko S, Joo N, Kim S, et al. Effect of functional yogurt NY-YP901 in improving the trait of metabolic syndrome. European journal of clinical nutrition. 2011; 65(11):1250-5.
17. Jahreis 0, Vogelsang H, Kiessling G, Schubert R, Bunte C, Hammes W. Influence of probiotic sausage (Lactobacillus paracasei) on blood lipids and immunological parameters of healthy volunteers. Food Research International. 2002; 35(2):133-8.
18. Jung S-P, Lee K-M, Kang J-H, Yun S-I, Park H-0, Moon Y, et al. Effect of Lactobacillus gasseri BNR17 on overweight and obese adults: a randomized, double-blind clinical trial. Korean journal of family medicine. 2013; 34(2):80-9.
19. Xiao J, Kondo S, Takahashi N, Miyaji K, Oshida K, Hiramatsu A, et al. Effects of milk products fermented by Bifidobacterium longum on blood lipids in rats and healthy adult male volunteers. Journal of dairy science. 2003; 86(7): 2452-61.
20. Hlivak P, Odraska J, Ferencik M, Ebringer L, Jahnova E, Mikes Z. One-year application of probiotic strain Enterococcus faecium M-74 decreases serum cholesterol levels. Bratisl Lek Listy. 2005; 106(2):67-72.
21. Ejtahed H, Mohtadi-Nia J, Homayouni-Rad A, Niafar M, Asghari-Jafarabadi M, Mofid V, et al. Effect of probiotic yogurt containing Lactobacillus acidophilus and Bifidobacterium lactis on lipid profile in individuals with type 2 diabetes mellitus. Journal of dairy science. 2011; 94(7):3288-94.
22. Ataie-Jafari A, Larijani B, Alavi Majd H, Tahbaz F. Cholesterol-lowering effect of probiotic yogurt in comparison with ordinary yogurt in mildly to moderately hypercholesterolemic subjects. Annals of Nutrition and Metabolism. 2009; 54(1):22-7.
23. Asemi Z, Samini M, Tabasi Z, talebian P, Azarbaz Z, Heydarzadeh Z et al. Effect of daily consumption of probiotic yoghurt on lipid profile in pregnant women: a randomized control clinical trial. The J Maternal-Fetal Neonatal Med 2012; 25(9): 1552-9.

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.