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Eftekhari Z. Garlic: A brief overview of its interaction with chemical drugs. pbp 2020; 2 (2) :31-32
URL: http://pbp.medilam.ac.ir/article-1-63-en.html
Research & Production Complex, Quality Control Department, Pasteur Institute of Iran, Alborz- Iran , z_eftekhari.vet@alumni.ut.ac.ir
Abstract:   (2223 Views)
Allium Sativum L. is a plant with different nutritional and medicinal principles. Despite the valuable medicinal effects that have been reported for the garlic plant, but drug interactions with chemical drugs have been reported. Garlic interacts with antihypertensive drugs, Saquinavir, hypoglycemics, general anesthetics, and anticoagulants, so associated use of garlic with mentioned chemical drugs should be used with caution to prevent drug interactions and side effects.
Full-Text [PDF 121 kb]   (1855 Downloads)    
Type of Study: Research |
Received: 2021/01/3 | Accepted: 2020/07/31 | Published: 2020/07/31

References
1. Eftekhari Z. Antimicrobial properties of medicinal plants; The new therapeutic aspect of Valeriana officinalis. Plant Biotechnol Persa. 2020; 2 (1): 59-60.
2. Abassi N, Ghaneialvar H, Shahsavari S. Natural remedies effective on stomachache in traditional medicine. Plant Biotechnol Persa. 2020; 2 (1): 42-47.
3. Velisek J. Kubec R. Davidek J. Chemical composition and classification of culinary and pharmaceutical garlic- based products. Z Lebensem Unters Forsch. 1997; 204: 161-164.
4. Blok E. The organosulfur chemistry of the genus allium implications for the organic chemistry of sulfur. Angew Chem Int Ed Eng. 1992; 31(9): 1135-78.
5. Buates S, Matlashewski G. Treatment of experimental Leishmaniasis with the immunomodulators imiquimod and S 28463: Efficacy and mode of action. J Infect Dis. 1999; 179(6): 1485-90.
6. Ledezma E. Apitz-Castro R. Ajoene the main active compound of garlic (Allium sativum): a new antifungal agent. Rev Iberoam Micol. 2006; 23: 75-80.
7. Chung LY. The antioxidant properties of garlic compounds: allyl cysteine, alliin, allicin, and allyl disulfide. J Med Food. 2006; 9: 205-213.
8. Sumioka I. Hayama M. Shimokawa Y. Shiraishi S. Tokunaga A. Lipid-lowering effect of monascus garlic fermented extract (MGFE) in hyperlipidemic subjects. Hiroshima J Med Sci. 2006; 55: 59-64.
9. Su CC. Chen GW. Tan TW. Lin JG. Chung JG. Crude extract of garlic induced caspase-3 gene expression leading to apoptosis in human colon cancer cells. In Vivo. 2006; 20: 85-90.
10. Mayeux PR. Agrawal KC. Tou JS. King BT. Lippton HL. Hyman Al. et al. The pharmacological effects of allicin a constituent of garlic oil. Agents and pharmacological effects of allicin, a constituent of garlic oil. Agents Actions. 1988; 25: 182-190.
11. Mc Grindle BW Helden E conner WT. Garlic extract therapy in children with hypercholesterlemia. Arc pediat Adolesc Med. 1998; 152: 1089-1094.
12. Isaacsohn JL. Moser M. stein EA. Dudley K. Davey JA. Liskov E. et al. Garlic powder and plasma lipids and lipoproteins: a multicenter, randomized, placebo-controlled trial. Arch lntern Med. 1998; 158: 1189-1194.
13. Koscienly J. Klussendorf D. Latza R. Schmitt R. Radtke H. Sieqel G. The antiatherosclerotic effect of Allium sativum. Atherosclerosis. 1999; 144: 237-249.
14. You WC. Blot WJ. Chang YS. Ershow A. Yang ZT. An Q. Allium vegetables and reduced risk of stomach cancer. J Natl Cancer Inst. 1989; 81: 162-164.
15. Sabayan B. Foroughinia F. Chohedry A. A postulated role of garlic organosulfur compounds in prevention of valproic acid hepatotoxicity. Med Hypotheses. 2007; 68: 512-514.
16. Block E. The chemistry of garlic and onions. Sci Amer. 1985; 252:14-119.
17. Brent J. Herbal drug interaction chart. http:// www.sdh.sk.ca/rxfiles. July 2002.
18. Mills S and Bone K. Principle and practice of phytotherapy (Modern herbal medicine). Churchill Livingstone. 2000: 104-7.
19. Warber S, Bancroft J, Pedroza J. Herbal Appendix. Clinics in Family Practice. 2002; 4:1-16.
20. http://www.vitalgoods.com/myibis/herbdru g.pdf.
21. Jones BD, Runikis RM. Interaction of Ginseng with phenelzine. J. Clin. Psychopharmacol. 1987; 7: 201-202.
22. http://www.bodyandfitness.com/bodyandfit ness1.html.
23. Mills S and Bone K. Principle and practice of phytotherapy (Modern herbal medicine). Churchill Livingstone. 2000: 104-7.

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