Volume 7, Issue 3 (7-2025)
pbp 2025, 7(3): 78-86 |
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Ghazizadeh F, Khalili N. Hypertension Treatment in Central Iran with Medicinal Plants: A Review of Ethnobotanical Evidence from Iran. pbp 2025; 7 (3) :78-86
URL: http://pbp.medilam.ac.ir/article-1-281-en.html
URL: http://pbp.medilam.ac.ir/article-1-281-en.html
1- Department of Pediatrics, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
2- Department of Cardiology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran ,dr_nkhalili@yahoo.com
2- Department of Cardiology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran ,
Abstract: (657 Views)
Objective: Hypertension refers to an abnormal increase in blood pressure against the arterial walls, leading to severe complications such as cardiovascular diseases, kidney failure, atherosclerosis, visual disorders, and strokes. The aim of this study was to identify medicinal plants in the western border regions of Iran that are used for managing hypertension.
Methods: This review study utilized keywords such as medicinal plants, hypertension, ethnobotany, Iran, and the provinces of Isfahan, Fars, Yazd, Markazi, Qom, Alborz, and Semnan to search for relevant articles. Databases including Google Scholar, SID, MegaIran, PubMed, and Scopus were employed for the search. Relevant ethnobotanical articles were selected for review and analysis.
Results: The findings indicate the effectiveness of several medicinal plants in controlling and managing hypertension. Medicinal plants such as Echium amoenum, Hyssopus officinalis, Rheum ribes, Valeriana officinalis, Silybum marianum, Mentha piperita, Thymus vulgaris, Bupleurum falcatum, Olea europaea, and Cinnamomum verum, and etc. with their anti-inflammatory, calming, and antioxidant properties, have demonstrated potential in reducing high blood pressure. These plants can serve as natural treatments for preventing cardiovascular diseases.
Conclusion: Studies suggest that medicinal plants with anti-inflammatory, calming, and antioxidant properties can effectively lower high blood pressure and prevent cardiovascular diseases. These plants hold promise as complementary natural treatments in the management of hypertension.
Methods: This review study utilized keywords such as medicinal plants, hypertension, ethnobotany, Iran, and the provinces of Isfahan, Fars, Yazd, Markazi, Qom, Alborz, and Semnan to search for relevant articles. Databases including Google Scholar, SID, MegaIran, PubMed, and Scopus were employed for the search. Relevant ethnobotanical articles were selected for review and analysis.
Results: The findings indicate the effectiveness of several medicinal plants in controlling and managing hypertension. Medicinal plants such as Echium amoenum, Hyssopus officinalis, Rheum ribes, Valeriana officinalis, Silybum marianum, Mentha piperita, Thymus vulgaris, Bupleurum falcatum, Olea europaea, and Cinnamomum verum, and etc. with their anti-inflammatory, calming, and antioxidant properties, have demonstrated potential in reducing high blood pressure. These plants can serve as natural treatments for preventing cardiovascular diseases.
Conclusion: Studies suggest that medicinal plants with anti-inflammatory, calming, and antioxidant properties can effectively lower high blood pressure and prevent cardiovascular diseases. These plants hold promise as complementary natural treatments in the management of hypertension.
Received: 2025/02/5 | Accepted: 2025/01/29 | Published: 2025/07/27
References
1. Fuchs, F. D., & Whelton, P. K. (2020). High blood pressure and cardiovascular disease. Hypertension, 75(2), 285-292.
2. Stamler, J. (1991). Blood pressure and high blood pressure. Aspects of risk. Hypertension, 18(3_supplement), I95.
3. Staessen, J. A., Wang, J., Bianchi, G., & Birkenhäger, W. H. (2003). Essential hypertension. The Lancet, 361(9369), 1629-1641.
4. Messerli, F. H., Williams, B., & Ritz, E. (2007). Essential hypertension. The Lancet, 370(9587), 591-603.
5. Oparil, S., Acelajado, M. C., Bakris, G. L., Berlowitz, D. R., Cífková, R., Dominiczak, A. F., ... & Whelton, P. K. (2018). Hypertension. Nature reviews. Disease primers, 4, 18014.
6. Mills, K. T., Stefanescu, A., & He, J. (2020). The global epidemiology of hypertension. Nature Reviews Nephrology, 16(4), 223-237.
7. Hermansen, K. (2000). Diet, blood pressure and hypertension. British Journal of Nutrition, 83(S1), S113-S119.
8. Kamyab, R., Namdar, H., Torbati, M., Ghojazadeh, M., Araj-Khodaei, M., & Fazljou, S. M. B. (2020). Medicinal plants in the treatment of hypertension: A review. Advanced Pharmaceutical Bulletin, 11(4), 601.
9. Sultana, S., & Muhammad Asif, H. (2017). Medicinal plants combating against hypertension: A green antihypertensive approach. Pakistan journal of pharmaceutical sciences, 30(6).
10. Chukwuma, C. I., Matsabisa, M. G., Ibrahim, M. A., Erukainure, O. L., Chabalala, M. H., & Islam, M. S. (2019). Medicinal plants with concomitant anti-diabetic and anti-hypertensive effects as potential sources of dual acting therapies against diabetes and hypertension: A review. Journal of ethnopharmacology, 235, 329-360.
11. Landazuri, P., Chamorro, N. L., & Cortes, B. P. (2017). Medicinal plants used in the management hypertension. J Anal Pharm Res, 5(2), 00134.
12. Bahmani E, Bahmani F, Abbaszadeh S. Ethnobotanical Study of Effective Medicinal Plants as Laxative (Anti-constipation): A Case Study in Arasbaran Forests, Northwest Iran. Journal of Biochemicals and Phytomedicine. 2023; 2(2): 59–63. doi: 10.34172/jbp.2023.12.
13. Ahmadi M, Khajoei Nejad F, Dastyar N. Identification of important herbs for anti-fever treatment: an ethnobotanical study of Sojas Rud, northwest Iran. Journal of Biochemicals and Phytomedicine. 2023; 2(2): 54–58. doi: 10.34172/jbp.2023.11.
14. Dastyar N, Lysiuk R. Identification of the most important medicinal plants used for wound healing: An ethnobotanical study of Sistan and Baluchestan province, Southeastern Iran. Journal of Biochemicals and Phytomedicine. 2023; 2(1): 16–19. doi: 10.34172/jbp.2023.4.
15. Negahdari S. Ethnobotanical study of medicinal plants used for management of diabetes mellitus in the east of Khuzestan, southwest Iran. Journal of Biochemicals and Phytomedicine. 2023; 2(1): 7-10. doi: 10.34172/jbp.2023.3.
16. Dastyar N, Ahmadi M. An ethnobotanical study of medicinal plants administered for the treatment of hyperlipidemia in Bushehr, South Iran. Journal of Biochemicals and Phytomedicine. 2022; 1(1): 26–30. doi: 10.34172/jbp.2022.7
17. Razmjooei D, Zarei Z, Akbari M. An ethnobotanical study of some medicinal plants in Abadeh county, located in Fars province. J Agric Plant Eco-Physiology. 7(3): 431-444. Islamic Azad University, Shahre-Qods Branch.
18. Abdi M, Hassanzadeh SR. Ethnobotanical study of medicinal plants in Arak county. J New Agric Research. 1(13): 5-25. Islamic Azad University, Arak Branch.
19. Dolatkhahi M, Dolatkhahi A, Bagher Nejad J. Ethnobotanical Study of Medicinal Plants Used in Arjan–Parishan Protected Area in Fars Province of Iran. Avicenna J Phytomed. 2014; 4(6): 402-412.
20. Dolatkhahi M, Dolatkhahi A, Bagher Nejad J. Ethnobotanical Study of Medicinal Plants Used in Arjan–Parishan Protected Area in Fars Province of Iran. Avicenna J Phytomed. 2014; 4(6): 402-412.
21. Ethnobotany of medicinal plants of sajasoroud. Saadatpour M, Barani H, Abedi Servastani A, Forooz M R. Journal of Medicinal Plants. Year; 8(3): 185-193. doi: 10.14196/JHD.2018.185.
22. Amirahmadi A, Ghamari F, Naderi R. An ethnobotanical study in some villages of Semnan County. Eco-phytochemical Journal of Medicinal Plants. 2023; 11(3):78-98.
23. Abtahi F S. Ethnobotanical study of some medicinal plants of Shazand County, Markazi Province. Journal of Medicinal Plants 2014; 18(2): 197-211.
24. Ramezanian M, Minaeifar AA: Ethnobotanical Study of Fasa. Journal of Islamic and Iranian Traditional Medicine. 2016; 7(2).
25. Mardani Nejad Sh, Vazirpoor M. Ethnobotanical study of medicinal plants used by people of Mobarakeh (Isfahan). Journal of Medicinal Plants. 2012; 3(2): 111-129
26. Abbasi Sh, Afshar S, Hojjaji A. Medicinal properties of some medicinal plant species in the region of Natanjan (Kabshabi). Journal of Medicinal Plants. 2012; 3(2): 147-156
27. Ziai S, Rezazadeh S, Dastpak A, Shabestari A, Taghizadeh M, Naghdibadi H et al . Study of the ACE Inhibitory Effect of Medicinal Plants Used in Iranian Folk-Medicine as Antihypertensive Remedy. J. Med. Plants 2006; 5 (20) :53-74.
28. Nikjou, P., Ranjbar Kookserai, S., Kashtkaran, Z., Kazemi, S. M., & Rouhaninasab, M. (2019). Review of the effect of medicinal plants on the control of hypertension and diabetes. First Research Congress of Students of Hormozgan University of Medical Sciences, Bandar Abbas. Available from: https://civilica.com/doc/996365
29. Mannami, A., Heidari, Sh., Kazemi, F., & Heidari, Sh. (2012). Report of experience and a review of medicinal plants effective on hypertension. Available from: https://sid.ir/paper/817062/fa
30. Dastyar N, Altememy D. Ethnobotanical study for hypertension treatment: An ethnobotanical study of Abadeh, South Iran. Journal of Biochemicals and Phytomedicine. 2022; 1(1): 13–16. doi: 10.34172/jbp.2022.4.
31. Baharvand-Ahmadi B, Bahmani M, Tajeddini P, Rafieian-Kopaei M, Naghdi N. An ethnobotanical study of medicinal plants administered for the treatment of hypertension. J Renal Inj Prev. 2016 Aug 9;5(3):123-128. doi: 10.15171/jrip.2016.26.
32. Dolatkhahi M, Nabipour I. Evaluation the ethnobotanical medicinal plants of epiphora region of Presian Golf northeast. J Med Plants. 2014;2:129-43.
33. Khodayari H, Amani SH, Amiri H. Ethnobotanical study of North east of Khuzistan province. Eco- Phytochemical Journal Of Medical Plants 2013;4:12-26.
34. Asadi-Samani M, Kafash-Farkhad N, Azimi N, Fasihi A, Alinia-Ahandani E, Rafieian-Kopaei M. Medicinal plants with hepatoprotective activity in Iranian folk medicine. Asian Pac J Trop Biomed. 2015;5:146-57.
35. Zolfaghari A, Adeli A, Mozafarian V, Babaei S, Habibi-Bibalan G. Identification of medicinal plants and indigenous knowledge of local people Arasbaran. J Med Arum Plants. 2013;28:534-50.
36. Mivefroshan A, Pirhadi M. A Review of Medicinal Plants Effective on Blood Pressure: An Ethnobotanical Review. pbp 2024; 6 (2) :25-30
37. Soleimany A, Kavandi H, Khalili N, Abbasi A, Ghaderi M, Abasi E, Hajizadeh R. The association between serum testosterone levels and coronary artery disease in men. Shiraz E-Med J. 2022;1;23(8): 116040.
38. Taleb H, Dargahi R, Shafipour H, Ghazizadeh F, Morwati S. Effect of radiosynovectomy with Rhenium-188 in the treatment of knee joint inflammation in patients with hemophilia. Journal of Iranian Medical Council. 2023 Jun 10.
39. Goudarzipour K, Ghazizadeh F, Tavassol HH, Behnam B. Warfarin-induced eosinophilia in a child with urkitt Lymphoma: a case report. Iranian Journal of Pharmaceutical Research: IJPR. 2015;14(3):887.
40. Lysiuk R. The Role of Biochemicals and Phytomedicine in Complementary Medicine and Modern Drug Discovery: Bridging Tradition and Innovation. J Biochem Phytomed2024; 3(2): 1-3. doi: 10.34172/jbp.2024.13.
41. Darvishi M, Nava AO, Karimi E, Nouri M, Meigooni SS, Hejripoor SZ. Human and animal bites. Caspian J Environ Sci. 2023;21(2):445–456.
42. Mahmud Hussen B, Noori M, Sayad B, Ebadi Fard Azar M, Sadri Nahand J, Bayat M, Babaei F, Karampour R, Bokharaei-Salim F, Mirzaei H, Moghoofei M. New potential MicroRNA biomarkers in human immunodeficiency virus elite controllers, human immunodeficiency virus infections, and coinfections with hepatitis B virus or hepatitis C virus. Intervirology. 2023 Dec 20;66(1):122–135.
43. Ghanbari A, Nouri M, Darvishi M. Evaluation of relationship between serum hemoglobin A1C level and severity of diabetic foot ulcers based on Wagner criteria. J Med Chem Sci. 2023;6:2234–2241.
44. Darvishi M, Nouri M, Zahir M, Asli M, Hejripoor SZ, Karimi E. Overview of human papillomavirus infection. Infect Disord Drug Targets. 2024 Mar 1;24(2):65–76.
45. Nouri M, Kamakifar P, Khodabandehlou N, Nahand JS, Tavakoli A, Norooznezhad F, Sorayyayi S, Babaei F, Mostafaei S, Moghoofei M. Association between Parvovirus B19 and anemia in HIV-infected patients. Med J Islam Repub Iran. 2019 Dec 16;33:137.
46. Darvishi M, Noori M, Nazer MR, Soleiman-Meigooni S, Forootan M. The relationship between Helicobacter pylori and extra-gastrointestinal infections. Iran J Med Microbiol. 2020 Nov 10;14(6):543–565.
47. Darvishi M, Hashemi Rafsanjani SMR, Nouri M, Abbaszadeh S, Heidari-Soureshjani S, Kasiri K, Rahimian G. Biological mechanisms of polyphenols against Clostridium difficile: A systematic review. Infect Disord Drug Targets. 2025 May;25(3): 18715265313944. doi: 10.2174/0118715265313944240726115600
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